تقرير
Treatment of Chronic Venous Ulcer with Cold Atmospheric Plasma Jet.
| العنوان: | Treatment of Chronic Venous Ulcer with Cold Atmospheric Plasma Jet. |
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| المؤلفون: | Samsavar S; Physics Department, Shahid Beheshti University, Tehran, Iran., Mahmoudi H; Autoimmune Bullous Diseases Research Center, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran., Khani MR; Laser - Plasma Research Institute, Shahid Beheshti University, Tehran, Iran., Daneshpazhooh M; Autoimmune Bullous Diseases Research Center, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran., Shokri B; Physics Department, Shahid Beheshti University, Tehran, Iran.; Laser - Plasma Research Institute, Shahid Beheshti University, Tehran, Iran. |
| المصدر: | Case reports in dermatology [Case Rep Dermatol] 2022 Nov 11; Vol. 14 (3), pp. 344-349. Date of Electronic Publication: 2022 Nov 11 (Print Publication: 2022). |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Karger Country of Publication: Switzerland NLM ID: 101517685 Publication Model: eCollection Cited Medium: Print ISSN: 1662-6567 (Print) Linking ISSN: 16626567 NLM ISO Abbreviation: Case Rep Dermatol Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel : Karger |
| مستخلص: | Nowadays, cold atmospheric plasma jet (CAP-jet) shows interesting results in the dermatology sector, particularly focusing on wound healing and antimicrobial properties. The purpose of this case report is to present a nonthermal atmospheric pressure plasma treatment as a novel therapy for venous ulcers. The plasma consists of ionized helium gas that is produced by a high-voltage (4.5 kV) and high-frequency power supply (22 kHz). We here present a 65-year-old man with a slow-healing ulcer on the right lower limb. The CAP was applied to the ulcer twice a week for four consecutive weeks and the patient was followed for 6 weeks. The amount of exudate, ulcer size, and wound grading were determined weekly. The results showed that exudate from the ulcer significantly reduced in the first week after complete treatment, the wound grading of the ulcer improved by the second week, and the size of the ulcer significantly decreased after 2 weeks. The ulcer entirely healed after 4 weeks without any signs of infection. This case study demonstrates that applying CAP-jet can decrease the bacterial load on the ulcer site and stimulate tissue regeneration concurrently. This increases the speed of the healing process. Competing Interests: The authors have no conflicts of interest to declare. (Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel.) |
| References: | Hautarzt. 2006 Oct;57(10):881-7. (PMID: 16317552) Oxid Med Cell Longev. 2019 Sep 3;2019:3873928. (PMID: 31565150) Ann Epidemiol. 2019 Jan;29:8-15. (PMID: 30497932) Sci Rep. 2021 Nov 9;11(1):21915. (PMID: 34753995) Indian Dermatol Online J. 2014 Jul;5(3):397-9. (PMID: 25165684) Dermatol Ther. 2021 Nov;34(6):e15169. (PMID: 34676656) Arch Med Res. 2013 Apr;44(3):169-77. (PMID: 23506720) Biomol Ther (Seoul). 2014 Nov;22(6):477-90. (PMID: 25489414) J Tissue Eng Regen Med. 2011 Aug;5(8):612-9. (PMID: 21774084) |
| فهرسة مساهمة: | Keywords: Chronic wounds; Cold atmospheric plasma; Plasma therapy; Venous ulcer |
| تواريخ الأحداث: | Date Created: 20221205 Latest Revision: 20221206 |
| رمز التحديث: | 20221206 |
| مُعرف محوري في PubMed: | PMC9710460 |
| DOI: | 10.1159/000527018 |
| PMID: | 36466755 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1662-6567 |
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| DOI: | 10.1159/000527018 |