دورية أكاديمية
Urinary Tract Infection in Pediatrics: Study of Uropathogens and Their Resistance in a Madrid Hospital.
| العنوان: | Urinary Tract Infection in Pediatrics: Study of Uropathogens and Their Resistance in a Madrid Hospital. |
|---|---|
| المؤلفون: | Rosado MR; Servicio de Pediatría, Hospital Universitario Infanta Elena, 28343 Madrid, Spain., Molina AG; Servicio de Pediatría, Hospital Universitario Infanta Elena, 28343 Madrid, Spain., Velasco AL; Servicio de Pediatría, Hospital Universitario Infanta Elena, 28343 Madrid, Spain., Chinchilla GC; Servicio de Pediatría, Hospital Universitario Infanta Elena, 28343 Madrid, Spain., Lana PV; Servicio de Pediatría, Hospital Universitario Infanta Elena, 28343 Madrid, Spain., Izquierdo EO; Servicio de Pediatría, Hospital Universitario Infanta Elena, 28343 Madrid, Spain., Vidal LS; Servicio de Microbiología, Hospital Universitario Fundacin Jimenez Diaz, 28040 Madrid, Spain. |
| المصدر: | Archivos espanoles de urologia [Arch Esp Urol] 2022 Nov; Vol. 75 (9), pp. 791-797. |
| نوع المنشور: | Review; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Iniestares Country of Publication: Spain NLM ID: 0064757 Publication Model: Print Cited Medium: Print ISSN: 0004-0614 (Print) Linking ISSN: 00040614 NLM ISO Abbreviation: Arch Esp Urol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Madrid : Iniestares |
| مواضيع طبية MeSH: | Urinary Tract Infections*/drug therapy , Urinary Tract Infections*/etiology , Pediatrics*, Child ; Humans ; Escherichia coli ; Cross-Sectional Studies ; Retrospective Studies ; Amoxicillin-Potassium Clavulanate Combination/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Cephalosporins/therapeutic use ; Hospitals ; Drug Resistance, Bacterial |
| مستخلص: | Introduction: Resistance to antibiotics is a growing problem with repercussions on the choice of first-line treatment in urinary tract infection (UTI) in childhood. Objectives: To know the current pattern of antibiotic susceptibility/resistance of the most frequent germs that cause UTI in our healthcare area. Secondary objective is to know the evolution of these patterns over time. Patients and Methods: A cross-sectional retrospective study of UTI episodes in a first-level hospital in two periods: 1st January 2008-31th December 2010 and 1st January 2017-31th December 2019 through a review of medical records, recording the following variables: Age, sex, fever, hospital admission, uropathy/bladder dysfunction, antibiotic prophylaxis. Results: First period: 174 UTI episodes (156 patients); Second period: 266 UTI episodes (218 patients). The most frequently isolated germ was E. coli , but in patients with uropathy or bladder dysfunction, the percentage of different germs is greater. A significant increase in resistance to amoxicillin/clavulanate (from 12.2 to 24%) is observed between both periods, it remains stable and in an acceptable range for gentamicin, cotrimoxazole and slightly increases to first-generation cephalosporins. In patients with uropathy/bladder dysfunction, resistance to all these antibiotics is significantly increased. Conclusions: The increased resistance of the most frequent uropathogens in the UTI of the pediatric population of our healthcare area to amoxicillin/clavulanate makes it unsuitable as empirical therapy. First-generation cephalosporins are an adequate alternative in patients without risk factors. |
| فهرسة مساهمة: | Keywords: antibiotic resistance; empirical treatment; urinary tract infection |
| المشرفين على المادة: | 74469-00-4 (Amoxicillin-Potassium Clavulanate Combination) 0 (Anti-Bacterial Agents) 0 (Cephalosporins) |
| تواريخ الأحداث: | Date Created: 20221206 Date Completed: 20221207 Latest Revision: 20221207 |
| رمز التحديث: | 20231215 |
| DOI: | 10.56434/j.arch.esp.urol.20227509.115 |
| PMID: | 36472062 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0004-0614 |
|---|---|
| DOI: | 10.56434/j.arch.esp.urol.20227509.115 |