Stereotactic Radiotherapy in Early-Stage Breast Cancer in Neoadjuvant and Exclusive Settings: A Systematic Review.
| العنوان: | Stereotactic Radiotherapy in Early-Stage Breast Cancer in Neoadjuvant and Exclusive Settings: A Systematic Review. |
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| المؤلفون: | Piras A; UO Radioterapia Oncologica, Villa Santa Teresa, Palermo, Italy., Sanfratello A; UO Radioterapia Oncologica, Villa Santa Teresa, Palermo, Italy., Boldrini L; UOC Radioterapia Oncologica - Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Dipartimento di Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Roma, Italy.; Università Cattolica del Sacro Cuore, Roma, Italy., D'Aviero A; Radiation Oncology, Mater Olbia Hospital, Olbia, Italy., Pernice G; UO Oncologia, Fondazione Istituto G. Giglio, Cefalù, Italy., Sortino G; UO Oncologia, Fondazione Istituto G. Giglio, Cefalù, Italy., Valerio MR; Università degli Studi di Palermo, Palermo, Italy.; UOC Oncologia Medica, AOUP 'P. Giaccone', Palermo, Italy., Gennari R; Division of Breast Surgery, Department of Surgical Oncology, HSR G. Giglio Foundation, Cefalù, Italy., D'Angelo I; Department of Radiology, Fondazione Istituto G. Giglio, Cefalù, Italy., Marazzi F; UOC Radioterapia Oncologica - Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Dipartimento di Diagnostica per immagini, Radioterapia Oncologica ed Ematologia, Roma, Italy., Angileri T; UO Radiologia, Villa Santa Teresa, Palermo, Italy., Daidone A; UO Radioterapia Oncologica, Villa Santa Teresa, Palermo, Italy. |
| المصدر: | Oncology research and treatment [Oncol Res Treat] 2023; Vol. 46 (3), pp. 116-123. Date of Electronic Publication: 2022 Dec 12. |
| نوع المنشور: | Systematic Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: S. Karger Country of Publication: Switzerland NLM ID: 101627692 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2296-5262 (Electronic) Linking ISSN: 22965270 NLM ISO Abbreviation: Oncol Res Treat Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel : S. Karger, [2014]- |
| مواضيع طبية MeSH: | Breast Neoplasms* , Radiosurgery*/methods, Humans ; Female ; Neoadjuvant Therapy |
| مستخلص: | Introduction: Breast cancer (BC) is one of the most common tumors; better screening policies and multidisciplinary approach allow personalized treatment. Radiotherapy (RT) plays a central role in the multimodal approach in BC, and recent evidence has shown the non-inferiority of hypofractionated treatments. The aim of this study was to describe the feasibility and validity of stereotactic RT (SBRT) in BC in a neoadjuvant and exclusive setting. Methods: A PubMed/MEDLINE and Embase systematic review was conducted to assess the role of radiomics in BC. The search strategy was "breast [All Fields] AND "stereotactic" [All Fields] AND "radiotherapy" [All Fields]" and only original articles referred to BC in humans in the English language were considered. Results: A total of 2,149 studies were obtained using the mentioned search strategy on PubMed and Embase. After the complete selection process, a total of 12 papers were considered eligible for the analysis of the results. SBRT in BC was described in 8 studies regarding neoadjuvant approach and 4 papers regarding exclusive approach. Conclusions: Relative low toxicity rates, the reduced treatment volumes in the neoadjuvant setting, and the possibility to replace surgery when not feasible in exclusive setting resulted to be main advantages for SBRT in BC. Current evidence shows that both the neoadjuvant and the definitive settings seem to be promising clinical scenarios for SBRT, especially for EBC. (© 2022 S. Karger AG, Basel.) |
| فهرسة مساهمة: | Keywords: Breast cancer; Radiotherapy; SBRT |
| تواريخ الأحداث: | Date Created: 20221212 Date Completed: 20230307 Latest Revision: 20230307 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1159/000528640 |
| PMID: | 36509043 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2296-5262 |
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| DOI: | 10.1159/000528640 |