دورية أكاديمية
Words matter: The language of difference in human genetics.
| العنوان: | Words matter: The language of difference in human genetics. |
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| المؤلفون: | Cho MK; Stanford Center for Biomedical Ethics, Stanford University, Stanford, CA; Departments of Medicine and Pediatrics, Stanford University, Stanford, CA. Electronic address: micho@stanford.edu., Duque Lasio ML; Division of Genetics & Genomic Medicine, Department of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO; Division of Laboratory and Genomic Medicine, Department of Pathology & Immunology, Washington University School of Medicine in St. Louis, St. Louis, MO., Amarillo I; Department of Pathology and Laboratory Medicine, Penn State College of Medicine, Penn State Health Milton S. Hershey Medical Center, Hershey, PA., Mintz KT; Stanford Center for Biomedical Ethics, Stanford University, Stanford, CA., Bennett RL; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA., Brothers KB; Norton Children's Research Institute Affiliated with the University of Louisville, Louisville, KY. |
| المصدر: | Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2023 Mar; Vol. 25 (3), pp. 100343. Date of Electronic Publication: 2022 Dec 15. |
| نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 9815831 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-0366 (Electronic) Linking ISSN: 10983600 NLM ISO Abbreviation: Genet Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2022- : [New York] : Elsevier Original Publication: Baltimore, MD : Lippincott, Williams & Wilkins, c1998- |
| مواضيع طبية MeSH: | Genetic Research* , Publishing*, Humans ; Delivery of Health Care ; Gender Identity ; Human Genetics |
| مستخلص: | Diversity, equity, and inclusion efforts in academia are leading publishers and journals to re-examine their use of terminology for commonly used scientific variables. This reassessment of language is particularly important for human genetics, which is focused on identifying and explaining differences between individuals and populations. Recent guidance on the use of terms and symbols in clinical practice, research, and publications is beginning to acknowledge the ways that language and concepts of difference can be not only inaccurate but also harmful. To stop perpetuating historical wrongs, those of us who conduct and publish genetic research and provide genetic health care must understand the context of the terms we use and why some usages should be discontinued. In this article, we summarize critiques of terminology describing disability, sex, gender, race, ethnicity, and ancestry in research publications, laboratory reports, diagnostic codes, and pedigrees. We also highlight recommendations for alternative language that aims to make genetics more inclusive, rigorous, and ethically sound. Even though norms of acceptable language use are ever changing, it is the responsibility of genetics professionals to uncover biases ingrained in professional practice and training and to continually reassess the words we use to describe human difference because they cause harm to patients. Competing Interests: Conflict of Interest The authors declare no conflicts of interest. (Copyright © 2022 American College of Medical Genetics and Genomics. Published by Elsevier Inc. All rights reserved.) |
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| معلومات مُعتمدة: | T32 HG008953 United States HG NHGRI NIH HHS |
| فهرسة مساهمة: | Keywords: Disability; Equity; Inclusivity; Race and ethnicity; Sex and gender |
| تواريخ الأحداث: | Date Created: 20221216 Date Completed: 20230308 Latest Revision: 20240302 |
| رمز التحديث: | 20240302 |
| مُعرف محوري في PubMed: | PMC9991958 |
| DOI: | 10.1016/j.gim.2022.11.011 |
| PMID: | 36524987 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1530-0366 |
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| DOI: | 10.1016/j.gim.2022.11.011 |