دورية أكاديمية
أعرض في EDS

Protein Supplementation during Mid-Gestation Alters the Amino Acid Patterns, Hepatic Metabolism, and Maternal Skeletal Muscle Turnover of Pregnant Zebu Beef Cows.

التفاصيل البيبلوغرافية
العنوان: Protein Supplementation during Mid-Gestation Alters the Amino Acid Patterns, Hepatic Metabolism, and Maternal Skeletal Muscle Turnover of Pregnant Zebu Beef Cows.
المؤلفون: Meneses JAM; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil.; Department of Veterinary Medicine and Animal Science, Universidad de Ciencias Aplicadas y Ambientales, Cartagena 130001, Bolivar, Colombia., Nascimento KB; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil., Galvão MC; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil., Ramírez-Zamudio GD; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil., Gionbelli TRS; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil., Ladeira MM; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil., Duarte MS; Department of Animal Bioscience, University of Guelph, Guelph, ON N1G 2W1, Canada., Casagrande DR; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil., Gionbelli MP; Department of Animal Science, Universidade Federal de Lavras, Lavras 37200-900, MG, Brazil.
المصدر: Animals : an open access journal from MDPI [Animals (Basel)] 2022 Dec 16; Vol. 12 (24). Date of Electronic Publication: 2022 Dec 16.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Molecular Diversity Preservation International Country of Publication: Switzerland NLM ID: 101635614 Publication Model: Electronic Cited Medium: Print ISSN: 2076-2615 (Print) Linking ISSN: 20762615 NLM ISO Abbreviation: Animals (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : Molecular Diversity Preservation International, 2011-
مستخلص: From 100 to 200 days of gestation, 52 cows carrying male ( n = 30) or female ( n = 22) fetuses were assigned to CON (basal diet-5.5% of CP, n = 26) or SUP (basal diet + protein supplement [40% CP, 3.5 g/kg BW]-12% of CP, n = 26) treatments. Glucose concentrations decreased at 200 ( p ≤ 0.01; CON = 46.9 and SUP = 54.7 mg/dL) and 270 days ( p ≤ 0.05; CON = 48.4 and SUP = 53.3 mg/dL) for CON compared to SUP. The same pattern occurred for insulin ( p ≤ 0.01). At parturition, the NEFA concentration was greater ( p = 0.01, 0.10 vs. 0.08 mmol/L) for CON than for SUP. Total AA increased in SUP ( p ≤ 0.03) at mid- and late-gestation compared to CON. At 200 days, CON dams carrying females had less essential AA ( p = 0.01) than cows carrying males. The SUP dams had greater expressions of protein synthesis markers, namely eIf4E and GSK3β ( p ≤ 0.04), at day 200 and of MuFR1 (protein degradation marker, p ≤ 0.04) at parturition. Supplemented cows had higher hepatic pyruvate carboxylase expressions ( p = 0.02). Therefore, PS alleviates the restriction overload on maternal metabolism.
Competing Interests: The authors declare no conflict of interest.
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معلومات مُعتمدة: Grant#427276/2018-7; Grant#311883/2018-4 CNPq-Conselho Nacional de Desenvolvimento Científico e Tecnológico; Grant#001 CAPES-Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Grant# 465377/2014-9 FAPEMIG-Fundação de Amparo à Pesquisa de MG and INCT-CA-Instituto Nacional de Ciência e Tecnologia de Ciência Animal
فهرسة مساهمة: Keywords: amino acids; gene expression; gluconeogenesis; maternal nutrition; skeletal muscle
تواريخ الأحداث: Date Created: 20221223 Latest Revision: 20221225
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9774392
DOI: 10.3390/ani12243567
PMID: 36552487
قاعدة البيانات: MEDLINE
الوصف
تدمد:2076-2615
DOI:10.3390/ani12243567