دورية أكاديمية
Bartonella quintana Transmitted by Head Lice: An Outbreak of Trench Fever in Senegal.
| العنوان: | Bartonella quintana Transmitted by Head Lice: An Outbreak of Trench Fever in Senegal. |
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| المؤلفون: | Hammoud A; Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; MEPHI, Aix Marseille Univ, IRD, AP-HM, Marseille, France., Louni M; Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; MEPHI, Aix Marseille Univ, IRD, AP-HM, Marseille, France., Fenollar F; Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; VITROME, Aix Marseille Univ, IRD, AP-HM, SSA, Marseille, France., Bassene H; Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; VITROME, Campus International Commun UCAD-IRD of Hann, IRD 257, Dakar, Senegal., Sambou M; Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; VITROME, Campus International Commun UCAD-IRD of Hann, IRD 257, Dakar, Senegal., Duclos N; Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; MEPHI, Aix Marseille Univ, IRD, AP-HM, Marseille, France., Diatta G; Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; VITROME, Campus International Commun UCAD-IRD of Hann, IRD 257, Dakar, Senegal., Sokhna C; Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; VITROME, Campus International Commun UCAD-IRD of Hann, IRD 257, Dakar, Senegal., Levasseur A; Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; VITROME, Aix Marseille Univ, IRD, AP-HM, SSA, Marseille, France., Raoult D; Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; MEPHI, Aix Marseille Univ, IRD, AP-HM, Marseille, France., Mediannikov O; Institut Hospitalo-Universitaire Méditerranée Infection, Marseille, France.; MEPHI, Aix Marseille Univ, IRD, AP-HM, Marseille, France. |
| المصدر: | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2023 Apr 17; Vol. 76 (8), pp. 1382-1390. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Jan. 2011- : Oxford : Oxford University Press Original Publication: Chicago, IL : The University of Chicago Press, c1992- |
| مواضيع طبية MeSH: | Bartonella quintana*/genetics , Pediculus*/genetics , Trench Fever*/epidemiology , Lice Infestations*/epidemiology, Animals ; Humans ; Senegal/epidemiology ; Disease Outbreaks ; DNA |
| مستخلص: | Background: Louse-borne trench fever caused by Bartonella quintana is a neglected public health concern, known to be transmitted from body louse feces via scratching. No viable B. quintana have ever been isolated from head lice before; therefore, their role as a vector is still poorly understood. Methods: In Senegal, the implementation of a permanent local surveillance system in a point-of-care laboratory (POC) allows the monitoring of emerging diseases. Here we used culture as well as molecular and genomic approaches to document an outbreak of trench fever associated with head lice in the village of Ndiop. Head lice and blood samples were collected from febrile patients between November 2010 and April 2015. Genomes of 2 isolated strains of B. quintana were sequenced and analyzed. Results: A total of 2289 blood samples were collected in the 2010-2015 period. From 2010-2013, B. quintana DNA was detected by polymerase chain reaction (PCR) in 0.25% (4/1580). In 2014, 228 blood samples were collected, along with 161 head lice from 5 individuals. B. quintana DNA was detected in 4.4% (10/228) of blood samples, and in lice specimens collected from febrile patients (61.7%, 50/81) and non-febrile patients (61.4%, 43/70). Two B. quintana strains were isolated from blood and head lice from 2 different patients. Genomic sequence analysis showed 99.98% overall similarity between both strains. Conclusions: The presence of live B. quintana in head lice, and the genetic identity of strains from patients' blood and head lice during a localized outbreak in Senegal, supports the evidence of head lice vectorial capacity. Competing Interests: Potential conflicts of interest. D. R. was one of the owners of the Arthrobac-Pharma company (that is now already closed) during the period of 2015–2021. D. R. also reports a role as scientific board member of Eurofins company; is founder and shareholder of a microbial culture company (Culture Top) and was a consultant with stock or stock options for Hitachi High-Technologies Corporation, Tokyo, Japan from 2018 to 2020. All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed. (© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.) |
| فهرسة مساهمة: | Keywords: Bartonella quintana; blood samples; genome; head lice; molecular analysis |
| المشرفين على المادة: | 9007-49-2 (DNA) |
| تواريخ الأحداث: | Date Created: 20221226 Date Completed: 20230419 Latest Revision: 20230421 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1093/cid/ciac937 |
| PMID: | 36571112 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1537-6591 |
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| DOI: | 10.1093/cid/ciac937 |