دورية أكاديمية
أعرض في EDS

Longitudinal Follow-Up Using the Heel Enthesitis Magnetic Resonance Imaging Scoring System (HEMRIS) Shows Minimal Changes in Heel Enthesitis Assessed in Spondyloarthritis and Psoriasis Patients.

التفاصيل البيبلوغرافية
العنوان: Longitudinal Follow-Up Using the Heel Enthesitis Magnetic Resonance Imaging Scoring System (HEMRIS) Shows Minimal Changes in Heel Enthesitis Assessed in Spondyloarthritis and Psoriasis Patients.
المؤلفون: Kleinrensink NJ; Department of Rheumatology & Clinical Immunology, UMC Utrecht, Utrecht University, 3584 CX Utrecht, The Netherlands.; Department of Radiology, UMC Utrecht, Utrecht University, 3584 CX Utrecht, The Netherlands., Foppen W; Department of Radiology, UMC Utrecht, Utrecht University, 3584 CX Utrecht, The Netherlands., Katen IT; Department of Radiology, UMC Utrecht, Utrecht University, 3584 CX Utrecht, The Netherlands., Leijten EFA; Department of Rheumatology, Sint Maartenskliniek, 6500 GM Nijmegen, The Netherlands., de Jong PA; Department of Radiology, UMC Utrecht, Utrecht University, 3584 CX Utrecht, The Netherlands., Spierings J; Department of Rheumatology & Clinical Immunology, UMC Utrecht, Utrecht University, 3584 CX Utrecht, The Netherlands.
المصدر: Journal of personalized medicine [J Pers Med] 2022 Oct 25; Vol. 12 (11). Date of Electronic Publication: 2022 Oct 25.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101602269 Publication Model: Electronic Cited Medium: Print ISSN: 2075-4426 (Print) Linking ISSN: 20754426 NLM ISO Abbreviation: J Pers Med Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, 2011-
مستخلص: Enthesitis is a common clinical feature of spondyloarthritis (SpA). For reliable assessment of enthesitis the Heel Enthesitis Magnetic Resonance Imaging Scoring System (HEMRIS) was developed. The aims of this study were to evaluate changes in HEMRIS over time and to evaluate whether these changes correlated with changes in clinical parameters. This single-center observational study followed patients with SpA and psoriasis, regardless of presence of clinical heel enthesitis, for two years. Clinical evaluation and ankle MRIs were performed annually. Changes in HEMRIS were compared at one-year intervals using the Wilcoxon signed-rank test. The association between changes in the HEMRIS with changes in clinical parameters was evaluated using Spearman's correlation coefficient. In total, 38 patients were included. An increase in the inflammatory and structural HEMRIS was identified in, respectively, 12 (17.9%) and 4 (6.0%) patients in one-year intervals. We found non-significant changes in the HEMRIS during longitudinal follow-up. Changes in the HEMRIS did not correlate with changes in local or general disease activity. Our results show that MRI-findings of enthesitis assessed with HEMRIS changed in a small number of patients in a one-year interval in an observational setting. Changes in HEMRIS were not associated with changes in clinical disease activity.
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معلومات مُعتمدة: NA Janssen Inc.; NA Health Holland, Top Sector Life Sciences & Health.
فهرسة مساهمة: Keywords: enthesitis; inflammation; magnetic resonance imaging; psoriasis; psoriatic arthritis; spondyloarthritis
تواريخ الأحداث: Date Created: 20221227 Latest Revision: 20230103
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC9693157
DOI: 10.3390/jpm12111765
PMID: 36573712
قاعدة البيانات: MEDLINE
الوصف
تدمد:2075-4426
DOI:10.3390/jpm12111765