دورية أكاديمية
A Case Report of Treatment-Resistant Agitation in Dementia With Lewy Bodies: Medical Marijuana as an Alternative to Antipsychotics.
| العنوان: | A Case Report of Treatment-Resistant Agitation in Dementia With Lewy Bodies: Medical Marijuana as an Alternative to Antipsychotics. |
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| المؤلفون: | Ramm RM; Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA., Lerner ZI; Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA., Levy-Meeks GS; Division of Geriatric and Palliative Medicine, Department of Medicine, University of Texas Houston School of Medicine, Houston, Texas, USA., Burke RV; Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA., Raven MC; Medical Director, Palliative Medicine Program, Our Lady of the Lake Regional Medical Center, Baton Rouge, Louisiana, USA., Song A; Department of Medicine, University of Texas Medical Branch, Galveston, Texas, USA., Glass MH; Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA. |
| المصدر: | Journal of palliative medicine [J Palliat Med] 2023 May; Vol. 26 (5), pp. 737-740. Date of Electronic Publication: 2022 Dec 26. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 9808462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7740 (Electronic) Linking ISSN: 15577740 NLM ISO Abbreviation: J Palliat Med Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Larchmont, NY : Mary Ann Liebert, Inc., c1998- |
| مواضيع طبية MeSH: | Antipsychotic Agents*/therapeutic use , Lewy Body Disease*/drug therapy , Medical Marijuana*/therapeutic use, Male ; Humans ; Aged, 80 and over ; Anxiety |
| مستخلص: | Palliative care teams are often consulted to assist in treating persistent dementia-related behavioral issues. Delta-9-tetrahydrocannabinol (THC) offers an alternative to traditional antipsychotic drugs in the long-term management of dementia with behavioral change. We present the case of an 85-year-old man with dementia with Lewy bodies with worsening aggression refractory to antipsychotic management. Multiple regimens of antipsychotics failed both in the outpatient and inpatient settings. After exhausting other options and in the setting of worsening agitation, a tincture of THC was prescribed. After starting THC tincture, the patient's behavior rapidly improved, and he was discharged home to the care of his spouse. The challenges of prescribing and obtaining THC are discussed. |
| فهرسة مساهمة: | Keywords: dementia; medical cannabis; neurodegenerative disease |
| المشرفين على المادة: | 0 (Antipsychotic Agents) 0 (Medical Marijuana) |
| تواريخ الأحداث: | Date Created: 20221228 Date Completed: 20230504 Latest Revision: 20230624 |
| رمز التحديث: | 20230625 |
| DOI: | 10.1089/jpm.2022.0343 |
| PMID: | 36576970 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1557-7740 |
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| DOI: | 10.1089/jpm.2022.0343 |