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Warfarin-induced isolated spontaneous subarachnoid hemorrhage: Rare case report.

التفاصيل البيبلوغرافية
العنوان: Warfarin-induced isolated spontaneous subarachnoid hemorrhage: Rare case report.
المؤلفون: Hassan MS; Department of Neurology, Mogadishu Somali Turkish Training and Research Hospital, Somalia., Bakir A; Department of Neurology, Mogadishu Somali Turkish Training and Research Hospital, Somalia., Adam BA; Department of Neurology, Mogadishu Somali Turkish Training and Research Hospital, Somalia., Sidow NO; Department of Neurology, Mogadishu Somali Turkish Training and Research Hospital, Somalia., Ibrahim AA; Department of Neurology, Mogadishu Somali Turkish Training and Research Hospital, Somalia., Abdi IA; Department of Cardiology, Mogadishu Somali Turkish Training and Research Hospital, Somalia., Waberi MM; Department of Cardiology, Mogadishu Somali Turkish Training and Research Hospital, Somalia.
المصدر: Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2022 Nov 17; Vol. 84, pp. 104946. Date of Electronic Publication: 2022 Nov 17 (Print Publication: 2022).
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Wolters Kluwer Country of Publication: England NLM ID: 101616869 Publication Model: eCollection Cited Medium: Print ISSN: 2049-0801 (Print) Linking ISSN: 20490801 NLM ISO Abbreviation: Ann Med Surg (Lond) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: 2023- : [London] : Wolters Kluwer
Original Publication: London : Surgical Associates Ltd., 2012-
مستخلص: Introduction and Importance: Subarachnoid hemorrhage (SAH) is mostly associated with head trauma. Non-traumatic subarachnoid hemorrhage is mostly due to vascular abnormalities: either hemorrhage from ruptured aneurysm or bleeding from arteriovenous malformation. Aneurysmal hemorrhage is the biggest cause in non-traumatic cases. Warfarin is associated with cerebral intraparenchymal hemorrhage, but it is rarely associated with SAH.
Case Presentation: Here, we report the case of a 45-year-old male patient who was admitted to the neurology ward of our hospital due to acute ischemic stroke. The patient was treated with a vitamin K antagonist (warfarin). However, on the third day, his condition deteriorated (his GCS regressed from 11/15 to 5/15). His pupils were anisocoric. Brain CT showed extensive subarachnoid hemorrhage without intraparenchymal involvement. Cerebral magnetic resonance angiography ruled out aneurysmal rupture. The patient was intubated and transferred to the intensive care unit. Due to his poor condition, neurosurgical intervention could not be done. The patient was managed conservatively, but the patient passed away 4 days later in the intensive care unit.
Clinical Discussion: Non-traumatic SAH is mostly caused by aneurysmal rupture. Warfarin increases the risk of intracranial hemorrhage and mostly causes intraparenchymal hemorrhage. Isolated warfarin-related SAH without parenchymal involvement is a rare event. Here we present a young male patient with an isolated warfarin-induced SAH.
Conclusion: Warfarin is rarely associated with isolated subarachnoid hemorrhage. This case highlights a young male patient with spontaneous SAH after warfarin therapy for acute ischemic stroke. Aneurysmal rupture and trauma should be excluded before a diagnosis of warfarin-induced SAH is made.
Competing Interests: The authors declare no conflict of interest.
(© 2022 The Authors.)
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فهرسة مساهمة: Keywords: Ischemic stroke; Subarachnoid hemorrhage; Warfarin
تواريخ الأحداث: Date Created: 20221230 Latest Revision: 20230103
رمز التحديث: 20240829
مُعرف محوري في PubMed: PMC9793204
DOI: 10.1016/j.amsu.2022.104946
PMID: 36582886
قاعدة البيانات: MEDLINE
الوصف
تدمد:2049-0801
DOI:10.1016/j.amsu.2022.104946