دورية أكاديمية

Mechanisms of late arrhythmia recurrence after initially successful pulmonary vein isolation in patients with atrial fibrillation.

التفاصيل البيبلوغرافية
العنوان: Mechanisms of late arrhythmia recurrence after initially successful pulmonary vein isolation in patients with atrial fibrillation.
المؤلفون: Erhard N; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.; Department of Electrophysiology, German Heart Center Munich, Technical University of Munich, Munchen, Germany., Mauer T; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany., Ouyang F; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.; Department of Cardiac Electrophysiology, University Heart Center, University Hospital Eppendorf, Hamburg, Germany., Sciacca V; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.; Clinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany., Rillig A; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.; Department of Cardiac Electrophysiology, University Heart Center, University Hospital Eppendorf, Hamburg, Germany., Reissmann B; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.; Department of Cardiac Electrophysiology, University Heart Center, University Hospital Eppendorf, Hamburg, Germany., Rottner L; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.; Department of Cardiac Electrophysiology, University Heart Center, University Hospital Eppendorf, Hamburg, Germany., Mathew S; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.; Department of Cardiology, University of Giessen, Giessen, Germany., Sohns C; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.; Department of Cardiac Electrophysiology, University Heart Center, University Hospital Eppendorf, Hamburg, Germany., Heeger CH; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.; University Heart Center Lübeck, Medical Clinic II (Department of Cardiology, Angiology and Intensive Care Medicine), University Hospital Schleswig-Holstein, Lübeck, Germany., Tilz RR; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.; University Heart Center Lübeck, Medical Clinic II (Department of Cardiology, Angiology and Intensive Care Medicine), University Hospital Schleswig-Holstein, Lübeck, Germany., Kuck KH; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.; University Heart Center Lübeck, Medical Clinic II (Department of Cardiology, Angiology and Intensive Care Medicine), University Hospital Schleswig-Holstein, Lübeck, Germany.; LANS CARDIO, Hamburg, Germany., Metzner A; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.; Department of Cardiac Electrophysiology, University Heart Center, University Hospital Eppendorf, Hamburg, Germany., Fink T; Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.; Clinic for Electrophysiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.
المصدر: Pacing and clinical electrophysiology : PACE [Pacing Clin Electrophysiol] 2023 Feb; Vol. 46 (2), pp. 161-168. Date of Electronic Publication: 2023 Jan 19.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Futura Pub. Co. Country of Publication: United States NLM ID: 7803944 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-8159 (Electronic) Linking ISSN: 01478389 NLM ISO Abbreviation: Pacing Clin Electrophysiol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Mount Kisco, N. Y. : Futura Pub. Co., c1978-
مواضيع طبية MeSH: Atrial Fibrillation* , Pulmonary Veins*/surgery , Catheter Ablation*/methods, Humans ; Recurrence ; Heart Atria ; Treatment Outcome
مستخلص: Background: Catheter ablation is an effective treatment for atrial fibrillation (AF,) but arrhythmia recurrence occurs in a relevant number of patients. Mechanisms of late occurring arrhythmias after ablation procedures are not fully understood. We analyzed electrophysiological mechanisms of early and late arrhythmia recurrences in patients who underwent radiofrequency-based catheter ablation of AF.
Methods and Results: Consecutive patients who underwent repeat ablation procedures after initial pulmonary vein isolation (PVI) for symptomatic arrhythmia recurrence were analyzed. A total of 110 consecutive patients who underwent catheter ablation for paroxysmal (79%) or persistent AF (21%) were included. Forty-seven patients suffered from early arrhythmia recurrence (group #1: 3-24 months), 29 patients from mid-term arrhythmia recurrences (group #2: 2-5 years), and 34 patients from late arrhythmia recurrences (group #3: > 5 years). Electrical PV reconnection was found in 98% in group #1, 72% in group #2 and 56% in group #3 (p < .001). Mode of arrhythmia recurrence was organized tachycardia in 25%, 28%, and 65% of patients in groups #1, #2, and #3 (p = .001), respectively. Patients with late arrhythmia recurrence had more pronounced left atrial low voltage as compared to patients with early arrhythmia recurrence based on two published scoring system.
Conclusion: Electrical PV reconnection was found in the majority of patients with early AF recurrence after PVI. In patients with late arrhythmia recurrences this mechanism may play an inferior role, with many patients presenting without PV reconnection, but with LA structural alterations. Thus, early and late occurring arrhythmia recurrence after catheter ablation may be the same symptom of different diseases.
(© 2023 The Authors. Pacing and Clinical Electrophysiology published by Wiley Periodicals LLC.)
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فهرسة مساهمة: Keywords: arrythmia recurrence; catheter ablation; pulmonary vein isolation
تواريخ الأحداث: Date Created: 20230102 Date Completed: 20230217 Latest Revision: 20230223
رمز التحديث: 20230223
DOI: 10.1111/pace.14656
PMID: 36588339
قاعدة البيانات: MEDLINE
الوصف
تدمد:1540-8159
DOI:10.1111/pace.14656