دورية أكاديمية
Asbestos fibers promote iron oxidation and compete with apoferritin enzymatic activity.
| العنوان: | Asbestos fibers promote iron oxidation and compete with apoferritin enzymatic activity. |
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| المؤلفون: | Zangari M; Department of Life Sciences, University of Trieste, Trieste, Italy., Borelli V; Department of Life Sciences, University of Trieste, Trieste, Italy., Bernareggi A; Department of Life Sciences, University of Trieste, Trieste, Italy., Zabucchi G; Department of Life Sciences, University of Trieste, Trieste, Italy. |
| المصدر: | Journal of toxicology and environmental health. Part A [J Toxicol Environ Health A] 2023 Feb 01; Vol. 86 (2-3), pp. 69-73. Date of Electronic Publication: 2023 Jan 02. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 100960995 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-7394 (Print) Linking ISSN: 00984108 NLM ISO Abbreviation: J Toxicol Environ Health A Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Washington, D.C. ; London : Taylor & Francis, c1998- |
| مواضيع طبية MeSH: | Iron*/metabolism , Asbestos*/toxicity, Apoferritins/chemistry ; Apoferritins/metabolism ; Ceruloplasmin/metabolism ; Ferritins/metabolism ; Oxidation-Reduction |
| مستخلص: | Asbestos fibers interact with many different proteins and may affect either their structure or functions. The aim of this study was to determine whether ferritin absorbed onto fibers might modify its ferroxidase activity. By measuring apo-ferritin ferroxidase activity, data demonstrated that ferritin in the presence of fibers did not significantly modify this enzymatic activity. However, fibers in the absence of ferritin promoted ferrous iron oxidation. Evidence suggests that asbestos fibers may promote iron oxidation and subsequently affect cellular iron homeostatic mechanisms. |
| فهرسة مساهمة: | Keywords: Asbestos; ferritin; iron |
| المشرفين على المادة: | E1UOL152H7 (Iron) 9013-31-4 (Apoferritins) EC 1.16.3.1 (Ceruloplasmin) 9007-73-2 (Ferritins) 1332-21-4 (Asbestos) |
| تواريخ الأحداث: | Date Created: 20230103 Date Completed: 20230123 Latest Revision: 20230224 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1080/15287394.2022.2164391 |
| PMID: | 36593716 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1528-7394 |
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| DOI: | 10.1080/15287394.2022.2164391 |