دورية أكاديمية
Mortality in hemodialysis patients in Ethiopia: a retrospective follow-up study in three centers.
| العنوان: | Mortality in hemodialysis patients in Ethiopia: a retrospective follow-up study in three centers. |
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| المؤلفون: | Desta BZ; Ethiopian Food, Medicine Administration and Health Care Authority, Addis Ababa, Ethiopia., Dadi AF; Menzies School of Health Research, Charles Darwin University, Darwin, Australia.; Departments of Epidemiology and Biostatistics, College of Medicine and Health Sciences, University of Gondar, Gondar, Amhara, Ethiopia., Derseh BT; School of Public Health, Asrat Woldeyes Health Sciences Campus, Debre Berhan University, Debre Berhan, Ethiopia. minastariku@gmail.com. |
| المصدر: | BMC nephrology [BMC Nephrol] 2023 Jan 04; Vol. 24 (1), pp. 3. Date of Electronic Publication: 2023 Jan 04. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 100967793 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2369 (Electronic) Linking ISSN: 14712369 NLM ISO Abbreviation: BMC Nephrol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BioMed Central, [2000- |
| مواضيع طبية MeSH: | Hypertension*/complications , Renal Insufficiency, Chronic*/mortality , Renal Insufficiency, Chronic*/therapy, Adult ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Ethiopia/epidemiology ; Follow-Up Studies ; Renal Dialysis ; Retrospective Studies ; Incidence |
| مستخلص: | Background: The prevalence of chronic kidney disease (CKD) is between 10 and 15% worldwide. Ethiopia is seeing a consistent increase in the number of dialysis patients. Patients on chronic hemodialysis have high mortality rates, but there is little information available in Ethiopia. Thus, this study looked into patient mortality and the factors that contributed to it at three dialysis centers in Addis Ababa for hemodialysis patients. Method: A facility-based retrospective follow-up study was employed among End-Stage Renal Disease patients on hemodialysis from 2016 to 2020 at St. Paul Millennium Medical College (SPMMC), Zewditu Memorial Hospital (ZMH), and Menelik II Hospital. The proportional hazard assumption was checked by using the Log (-log (St)) plots and tests. Life-table analysis was fitted to estimate the one and five-year's survival probability of these patients and Cox Proportional regression analysis to model the predictors of mortality at p-value < 0.05. Result: Over the course of 2772 person-months, 139 patients were tracked. Of these patients, 88 (63.3%) were male and the mean age (± SD) of the patients was 36.8 (± 11.9) years. During the follow-up period, 24 (17%) of the patients died, 67 (48.2%) were alive, 43 (30.9%) received a kidney transplant, and 5 (3.6%) were lost to follow-up. The mean survival time was 46.2 months (95% CI: 41.8, 50.5). According to estimates, there were 104 deaths per 1000 person-years at the end of the follow-up period. The likelihood that these patients would survive for one and 5 years was 91%% and 65%, respectively. Our analysis showed that patients with hypertension (Adjusted Hazard Rate (AHR) = 4.33; 95% CI: 1.02, 34.56), cardiovascular disease (AHR = 4.69; 95% CI: 1.32, 16.80), and infection during dialysis (AHR = 3.89; 95% CI: 1.96, 13.80) were more likely to die. Conclusion: The hemodialysis patients' death rate in the chosen dialysis facilities was high. Preventing and treating comorbidities and complications during dialysis would probably reduce the mortality of CKD patients. Furthermore, the best way to avoid and manage chronic kidney disease is to take a complete and integrated approach to manage hypertension, diabetes, and obesity. (© 2023. The Author(s).) |
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| فهرسة مساهمة: | Keywords: Chronic kidney diseases; Hemodialysis patients; Incidence; Mortality |
| تواريخ الأحداث: | Date Created: 20230104 Date Completed: 20230120 Latest Revision: 20230203 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1186/s12882-022-03053-6 |
| PMID: | 36600194 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1471-2369 |
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| DOI: | 10.1186/s12882-022-03053-6 |