دورية أكاديمية
Oral granulomatosis with polyangiitis a systematic review.
| العنوان: | Oral granulomatosis with polyangiitis a systematic review. |
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| المؤلفون: | Labrador AJP; Centro de Odontologia Integral, Acarigua, Venezuela.; Department of Diagnostic Sciences, Texas A&M University School of Dentistry, Texas, Estados Unidos., Valdez LHM; Diagnocentrobucal, Lima, Peru., Marin NRG; Department of Otolaryngologist, Military Hospital Bogota Colombia, Bogotá, Colombia., Ibazetta KAR; Oral and Maxilofacial Pathology and Medicine Clinics Department, Lima, Peru., Chacón JAL; Dental spa C.A., San Cristobal, Tachira, Venezuela., Fernandez AJV; Centro Médico Odontológico ODOMED, Caracas, Venezuela., Valencia MSV; Oral Surgery Department, Dental School, Universidad Internacional de Ecuador, Quito, Ecuador., Marchant SW; Doctoral Program in Morphological Sciences, Universidad de la Frontera, Temuco, Chile., Sanchez KBT; Clinical Dental New Hope, Lima, Peru., Villacrez CA; Dental Implant Department, Universidad Señor de SIPAN Dental School, Lima, Peru. |
| المصدر: | Clinical and experimental dental research [Clin Exp Dent Res] 2023 Feb; Vol. 9 (1), pp. 100-111. Date of Electronic Publication: 2023 Jan 04. |
| نوع المنشور: | Systematic Review; Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley Country of Publication: United States NLM ID: 101692332 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2057-4347 (Electronic) Linking ISSN: 20574347 NLM ISO Abbreviation: Clin Exp Dent Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Hoboken : Wiley, [2015]- |
| مواضيع طبية MeSH: | Granulomatosis with Polyangiitis*/diagnosis , Granulomatosis with Polyangiitis*/therapy , Granulomatosis with Polyangiitis*/complications, Female ; Humans ; Child ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Antibodies, Antineutrophil Cytoplasmic/therapeutic use ; Cyclophosphamide/therapeutic use |
| مستخلص: | Objective: Granulomatosis with polyangiitis is an unusual multisystemic inflammatory disease, with vasculitis of small- and medium-sized vessels, with a predilection for upper lower airways and kidneys. The etiology remains unknown although it may originate from different stimuli, in genetically susceptible patients. Materials and Methods: A detailed database search was performed. The variables were demographics, localization, histopathological findings, antineutrophil cytoplasmic autoantibody, cytoplasmic (c-ANCA) tests, treatment, and follow-up. Results: Fifty-two cases were identified; the mean age was 49.6 years, with a range from 6 to 87 years. It was most frequently seen in females (57.7%). The most common race was white (59.6%). The most frequent location was in the maxillary gingiva (28.8%), followed by both the upper and lower gingiva (19.2%). The most common clinical presentation was "strawberry gingivitis" (61.5%). The main symptom was pain, in 50%. Regarding the c-ANCA test, it was positive in 71.2% of cases. The most common therapy was prednisone and cyclophosphamide, utilized in 51.9%. The average follow-up was 23.6 months, and 88.5% of patients were still alive at follow-up. Conclusion: The diagnosis initially was difficult to establish, an early diagnosis and treatment are mandatory. If untreated the disease can be associated with morbidity and mortality. For the oral clinician, this disease needs to be addressed in the differential diagnosis of oral lesions. (© 2023 The Authors. Clinical and Experimental Dental Research published by John Wiley & Sons Ltd.) |
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| فهرسة مساهمة: | Keywords: antineutrophil cytoplasmic; gingivitis; granulomatosis with polyangiitis |
| المشرفين على المادة: | 0 (Antibodies, Antineutrophil Cytoplasmic) 8N3DW7272P (Cyclophosphamide) |
| تواريخ الأحداث: | Date Created: 20230105 Date Completed: 20230217 Latest Revision: 20230321 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC9932239 |
| DOI: | 10.1002/cre2.706 |
| PMID: | 36600477 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2057-4347 |
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| DOI: | 10.1002/cre2.706 |