دورية أكاديمية
أعرض في EDS

Impaired Left Ventricular Contractile Reserve in Patients With Hypertrophic Cardiomyopathy and Abnormal Blood Pressure Response: A Stress Echocardiographic Study.

التفاصيل البيبلوغرافية
العنوان: Impaired Left Ventricular Contractile Reserve in Patients With Hypertrophic Cardiomyopathy and Abnormal Blood Pressure Response: A Stress Echocardiographic Study.
المؤلفون: Takeoka M; Department of Cardiology, Matsushita Memorial Hospital, Moriguchi, JPN., Yamano M; Department of Cardiology, Matsushita Memorial Hospital, Moriguchi, JPN.; Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine, Kyoto, JPN., Honda S; Department of Cardiology, Matsushita Memorial Hospital, Moriguchi, JPN., Sakai C; Department of Cardiology, Matsushita Memorial Hospital, Moriguchi, JPN., Kawasaki T; Department of Cardiology, Matsushita Memorial Hospital, Moriguchi, JPN.
المصدر: Cureus [Cureus] 2022 Dec 02; Vol. 14 (12), pp. e32145. Date of Electronic Publication: 2022 Dec 02 (Print Publication: 2022).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Palo Alto, CA : Cureus, Inc.
مستخلص: Background: Abnormal blood pressure response (ABPR) has been reported to be a risk factor for sudden cardiac death in patients with hypertrophic cardiomyopathy (HCM). We aimed to elucidate the relationship between ABPR during exercise stress echocardiography (ESE) and impaired left ventricular (LV) contractile reserve based on two-dimensional strain in patients with HCM.
Methods: Patients with HCM underwent ESE with treadmill exercise. Patients whose blood pressure elevation at maximum workload was lower than 20 mmHg from baseline were classified as having ABPR. Echocardiographic parameters were compared between patients with and without ABPR.  Results: Of 26 patients with HCM, nine patients were diagnosed with ABPR. Significant LV outflow tract obstruction (>50 mmHg) was provoked only in one patient with ABPR (baseline to the conclusion of the exercise, 15.2 mmHg to 63.0 mmHg). Change in cardiac output (CO) and the ratio of early diastolic velocity to early annular velocity (E/e') from baseline to just after the conclusion of exercise did not differ between patients with and without ABPR (CO, 102±40% vs. 122±45%, P = 0.19; E/e', 4±22% vs. 2±20%, P = 0.86). Change in systemic vascular resistance change was not significant (patients with vs. without ABPR, -52±10% vs. -46±13%, P = 0.24). Percent change in LV global longitudinal strain was lower in patients with ABPR than patients without ABPR (12±17% vs. 27±15%, P = 0.02).
Conclusion: In conclusion, impaired LV contractile reserve during exercise might contribute to ABPR in patients with HCM.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2022, Takeoka et al.)
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فهرسة مساهمة: Keywords: 2d-speckle tracking; abnormal blood pressure response; doppler echocariography; exercise stress echocardiography; hypertrophic cardiomyopathy
تواريخ الأحداث: Date Created: 20230105 Latest Revision: 20230111
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9806187
DOI: 10.7759/cureus.32145
PMID: 36601194
قاعدة البيانات: MEDLINE
الوصف
تدمد:2168-8184
DOI:10.7759/cureus.32145