دورية أكاديمية
Neuropsychological and mental health concerns in a multicenter clinical sample of youth with turner syndrome.
| العنوان: | Neuropsychological and mental health concerns in a multicenter clinical sample of youth with turner syndrome. |
|---|---|
| المؤلفون: | Kremen J; Division of Endocrinology, Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts, USA., Davis SM; Department of Pediatrics, University of Colorado, Aurora, Colorado, USA.; eXtraOrdinary Kids Turner Syndrome Clinic, Children's Hospital Colorado, Aurora, Colorado, USA., Nahata L; Center for Biobehavioral Health, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.; Division of Endocrinology, Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio, USA., Kapa HM; Center for Biobehavioral Health, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA., Dattilo TM; Center for Biobehavioral Health, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA., Liu E; Division of Endocrinology, Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts, USA.; Institutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, Massachusetts, USA., Hutaff-Lee C; Department of Pediatrics, University of Colorado, Aurora, Colorado, USA., Tishelman AC; Boston College, Department of Psychology and Neuroscience, Boston, Massachusetts, USA., Crerand CE; Center for Biobehavioral Health, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.; Division of Endocrinology, Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio, USA. |
| المصدر: | American journal of medical genetics. Part A [Am J Med Genet A] 2023 Apr; Vol. 191 (4), pp. 962-976. Date of Electronic Publication: 2023 Jan 06. |
| نوع المنشور: | Multicenter Study; Journal Article; Research Support, N.I.H., Extramural |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101235741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4833 (Electronic) Linking ISSN: 15524825 NLM ISO Abbreviation: Am J Med Genet A Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Hoboken, N.J. : Wiley-Blackwell Original Publication: Hoboken, N.J. : Wiley-Liss, c2003- |
| مواضيع طبية MeSH: | Turner Syndrome*/diagnosis, Female ; Child ; Child, Preschool ; Humans ; Adolescent ; Mental Health ; Menarche ; Karyotype ; Karyotyping |
| مستخلص: | Clinical practice guidelines for individuals with Turner syndrome (TS) recommend screening for neuropsychological concerns (NC) and mental health concerns (MHC). However, current provider screening and referral patterns for NC and MHC are not well characterized. Additionally, prevalence of and risk factors for NC and MHC vary across studies. This multicenter chart review study examined the prevalence, risk factors for, and management of NC and MHC in a cohort of 631 patients with TS from three pediatric academic medical centers. NC and/or MHC were documented for 48.2% of patients. Neuropsychological evaluation recommendations were documented for 33.9% of patients; 65.4% of the sample subsequently completed these evaluations. Mental health care recommendations were documented in 35.0% of records; subsequent documentation indicated that 69.7% of these patients received such services. Most notably, rates of documented MHC, NC, and related referrals differed significantly by site, suggesting the need for standardized screening and referral practices. TS diagnosis in early childhood was associated with an increased risk of NC. Spontaneous menarche was associated with increased risk of MHC. Younger age at growth hormone initiation was associated with both increased risk of isolated NC and co-occurring NC and MHC. Mosaic karyotype was associated with decreased risk of NC and MHC. (© 2023 Wiley Periodicals LLC.) |
| References: | Arch Sex Behav. 2020 Feb;49(2):769-786. (PMID: 31598804) Neuropsychol Rev. 2018 Jun;28(2):188-215. (PMID: 29704077) Am J Med Genet A. 2005 Dec 1;139A(2):57-66. (PMID: 16252273) J Autism Dev Disord. 2003 Feb;33(1):55-67. (PMID: 12708580) Dev Disabil Res Rev. 2009;15(4):270-8. (PMID: 20014362) Ann Epidemiol. 2016 Mar;26(3):222-6. (PMID: 26851824) J Clin Endocrinol Metab. 2019 Nov 1;104(11):5073-5083. (PMID: 31009056) Am J Med Genet C Semin Med Genet. 2019 Mar;181(1):126-134. (PMID: 30767374) J Neurodev Disord. 2021 Oct 27;13(1):51. (PMID: 34706642) J Clin Endocrinol Metab. 2022 Mar 24;107(4):e1382-e1389. (PMID: 34893832) Adv Clin Exp Med. 2018 Feb;27(2):229-236. (PMID: 29521067) J Affect Disord. 2019 Feb 15;245:697-701. (PMID: 30447568) J Adolesc Health. 1996 Jul;19(1):34-8. (PMID: 8842858) J Pediatr Adolesc Gynecol. 2023 Apr;36(2):122-127. (PMID: 36216307) NCHS Data Brief. 2020 Mar;(358):1-8. (PMID: 32487288) Horm Res Paediatr. 2022;95(1):68-75. (PMID: 35313316) J Clin Endocrinol Metab. 2011 Feb;96(2):E278-87. (PMID: 21047929) J Pediatr. 2003 Oct;143(4):451-6. (PMID: 14571218) Eur J Endocrinol. 2017 Sep;177(3):G1-G70. (PMID: 28705803) JAMA. 2006 Mar 22;295(12):1374-6. (PMID: 16551707) Hum Reprod. 2013 Jun;28(6):1598-609. (PMID: 23539610) J Psychiatr Res. 2015 Sep;68:217-25. (PMID: 26228422) Child Psychiatry Hum Dev. 2016 Jun;47(3):440-58. (PMID: 26266467) Horm Res Paediatr. 2020;93(11-12):643-650. (PMID: 33915553) J Clin Endocrinol Metab. 1996 Mar;81(3):926-31. (PMID: 8772552) J Child Psychol Psychiatry. 1995 Oct;36(7):1109-25. (PMID: 8847375) J Pediatr Psychol. 2006 Oct;31(9):945-55. (PMID: 16524959) J Pediatr. 2006 Jan;148(1):95-101. (PMID: 16423606) Genet Couns. 1993;4(3):169-79. (PMID: 8267923) J Psychosom Obstet Gynaecol. 2017 Mar;38(1):45-52. (PMID: 27584042) Gynecol Endocrinol. 2004 Dec;19(6):313-9. (PMID: 15726728) J Pediatr Endocrinol Metab. 2007 Jun;20(6):677-84. (PMID: 17663292) J Pediatr. 2006 Jan;148(1):102-7. (PMID: 16423607) Clin Endocrinol (Oxf). 2020 May;92(5):434-442. (PMID: 32003479) Arch Clin Neuropsychol. 2022 May 16;37(4):789-797. (PMID: 34747436) MMWR Suppl. 2022 Feb 25;71(2):1-42. (PMID: 35202359) Child Care Health Dev. 2020 Jan;46(1):46-55. (PMID: 31322282) |
| معلومات مُعتمدة: | K23 HD092588 United States HD NICHD NIH HHS |
| فهرسة مساهمة: | Keywords: mental health; monosomy X; multidisciplinary clinics; neuropsychology; turner syndrome |
| تواريخ الأحداث: | Date Created: 20230106 Date Completed: 20230314 Latest Revision: 20240402 |
| رمز التحديث: | 20240402 |
| مُعرف محوري في PubMed: | PMC10031628 |
| DOI: | 10.1002/ajmg.a.63103 |
| PMID: | 36608170 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1552-4833 |
|---|---|
| DOI: | 10.1002/ajmg.a.63103 |