دورية أكاديمية

Loci Associated with Negative Heterosis for Viability and Meat Productivity in Interspecific Sheep Hybrids.

التفاصيل البيبلوغرافية
العنوان: Loci Associated with Negative Heterosis for Viability and Meat Productivity in Interspecific Sheep Hybrids.
المؤلفون: Zlobin AS; Kurchatov Genomic Center, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences SB RAS, 630090 Novosibirsk, Russia., Volkova NA; L.K. Ernst Federal Science Center for Animal Husbandry, 101000 Moscow, Russia., Zinovieva NA; L.K. Ernst Federal Science Center for Animal Husbandry, 101000 Moscow, Russia., Iolchiev BS; L.K. Ernst Federal Science Center for Animal Husbandry, 101000 Moscow, Russia., Bagirov VA; L.K. Ernst Federal Science Center for Animal Husbandry, 101000 Moscow, Russia., Borodin PM; Institute of Cytology and Genetics, SB RAS, 630090 Novosibirsk, Russia., Axenovich TI; Institute of Cytology and Genetics, SB RAS, 630090 Novosibirsk, Russia., Tsepilov YA; Kurchatov Genomic Center, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences SB RAS, 630090 Novosibirsk, Russia.
المصدر: Animals : an open access journal from MDPI [Animals (Basel)] 2023 Jan 03; Vol. 13 (1). Date of Electronic Publication: 2023 Jan 03.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Molecular Diversity Preservation International Country of Publication: Switzerland NLM ID: 101635614 Publication Model: Electronic Cited Medium: Print ISSN: 2076-2615 (Print) Linking ISSN: 20762615 NLM ISO Abbreviation: Animals (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : Molecular Diversity Preservation International, 2011-
مستخلص: Negative heterosis can occur on different economically important traits, but the exact biological mechanisms of this phenomenon are still unknown. The present study focuses on determining the genetic factors associated with negative heterosis in interspecific hybrids between domestic sheep ( Ovis aries ) and argali ( Ovis ammon ). One locus (rs417431015) associated with viability and two loci (rs413302370, rs402808951) associated with meat productivity were identified. One gene ( ARAP2 ) was prioritized for viability and three for meat productivity ( PDE2A, ARAP1, and PCDH15 ). The loci associated with meat productivity were demonstrated to fit the overdominant inheritance model and could potentially be involved int negative heterosis mechanisms.
Competing Interests: The authors declare no conflict of interest.
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معلومات مُعتمدة: 075-15-2019-1662 Kurchatov Genomics Center of IC&G
فهرسة مساهمة: Keywords: heterosis; overdominant model of inheritance; sheep
تواريخ الأحداث: Date Created: 20230108 Latest Revision: 20230111
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC9817718
DOI: 10.3390/ani13010184
PMID: 36611792
قاعدة البيانات: MEDLINE
الوصف
تدمد:2076-2615
DOI:10.3390/ani13010184