دورية أكاديمية
أعرض في EDS

Risk stratification of sudden cardiac death in asymptomatic female Brugada syndrome patients: A literature review.

التفاصيل البيبلوغرافية
العنوان: Risk stratification of sudden cardiac death in asymptomatic female Brugada syndrome patients: A literature review.
المؤلفون: Leung KSK; Cardiac Electrophysiology Unit, Cardiovascular Analytics Group, Hong Kong, China.; Faculty of Health and Life Sciences, Aston University Medical School, Birmingham, UK., Radford D; Kent and Medway Medical School, University of Kent and Canterbury Christ Church University, Canterbury, UK., Huang H; University of Medicine and Health Science, Royal College of Surgeons in Ireland, Dublin, Ireland., Lakhani I; Cardiac Electrophysiology Unit, Cardiovascular Analytics Group, Hong Kong, China., Li CKH; John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, UK., Hothi SS; Heart and Lung Centre, New Cross Hospital, Royal Wolverhampton NHS Trust, Wolverhampton, UK., Wai AKC; Emergency Medicine Unit, University of Hong Kong, Hong Kong, China., Liu T; Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China., Tse G; Cardiac Electrophysiology Unit, Cardiovascular Analytics Group, Hong Kong, China.; Kent and Medway Medical School, University of Kent and Canterbury Christ Church University, Canterbury, UK.; Emergency Medicine Unit, University of Hong Kong, Hong Kong, China., Lee S; Cardiac Electrophysiology Unit, Cardiovascular Analytics Group, Hong Kong, China.
المصدر: Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc [Ann Noninvasive Electrocardiol] 2023 Mar; Vol. 28 (2), pp. e13030. Date of Electronic Publication: 2023 Jan 11.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Wiley Periodicals, Inc Country of Publication: United States NLM ID: 9607443 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1542-474X (Electronic) Linking ISSN: 1082720X NLM ISO Abbreviation: Ann Noninvasive Electrocardiol Subsets: MEDLINE
أسماء مطبوعة: Publication: Malden, MA : Wiley Periodicals, Inc.
Original Publication: Armonk, NY : Futura Pub. Co.,
مواضيع طبية MeSH: Brugada Syndrome*/complications , Brugada Syndrome*/diagnosis , Brugada Syndrome*/epidemiology, Humans ; Male ; Female ; Risk Assessment ; Electrocardiography/adverse effects ; Death, Sudden, Cardiac/etiology ; Death, Sudden, Cardiac/epidemiology ; Risk Factors
مستخلص: Background and Objectives: Risk stratification in Brugada syndrome remains a difficult problem. Given the male predominance of this disease and their elevated risks of arrhythmic events, affected females have received less attention. It is widely known that symptomatic patients are at increased risk of sudden cardiac death (SCD) than asymptomatic patients, while this might be true in the male population; recent studies have shown that this association might not be significant in females. Over the past few decades, numerous markers involving clinical symptoms, electrocardiographic (ECG) indices, and genetic tests have been explored, with several risk-scoring models developed so far. The objective of this study is to review the current evidence of clinical and ECG markers as well as risk scores on asymptomatic females with Brugada syndrome.
Findings: Gender differences in ECG markers, the yield of genetic findings, and the applicability of risk scores are highlighted.
Conclusions: Various clinical, electrocardiographic, and genetic risk factors are available for assessing SCD risk amongst asymptomatic female BrS patients. However, due to the significant gender discrepancy in BrS, the SCD risk amongst females is often underestimated, and there is a lack of research on female-specific risk factors and multiparametric risk scores. Therefore, multinational studies pooling female BrS patients are needed for the development of a gender-specific risk stratification approach amongst asymptomatic BrS patients.
(© 2023 The Authors. Annals of Noninvasive Electrocardiology published by Wiley Periodicals LLC.)
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فهرسة مساهمة: Keywords: Brugada syndrome; gender difference; risk stratification; sudden cardiac death
تواريخ الأحداث: Date Created: 20230111 Date Completed: 20230321 Latest Revision: 20230322
رمز التحديث: 20230322
مُعرف محوري في PubMed: PMC10023885
DOI: 10.1111/anec.13030
PMID: 36628595
قاعدة البيانات: MEDLINE
الوصف
تدمد:1542-474X
DOI:10.1111/anec.13030