دورية أكاديمية
أعرض في EDS

Pulmonary function three to five months after hospital discharge for COVID-19: a single centre cohort study.

التفاصيل البيبلوغرافية
العنوان: Pulmonary function three to five months after hospital discharge for COVID-19: a single centre cohort study.
المؤلفون: Krueger T; Department of Clinical Epidemiology, VieCuri Medical Centre, Venlo, The Netherlands., van den Heuvel J; Department of Clinical Epidemiology, VieCuri Medical Centre, Venlo, The Netherlands., van Kampen-van den Boogaart V; Department of Pulmonology, VieCuri Medical Centre, Venlo, The Netherlands., van Zeeland R; Department of Pulmonology, VieCuri Medical Centre, Venlo, The Netherlands., Mehagnoul-Schipper DJ; Department of Intensive Care, VieCuri Medical Centre, Venlo, The Netherlands., Barten DG; Department of Emergency Medicine, VieCuri Medical Centre, Venlo, The Netherlands., Knarren L; Department of Internal Medicine, VieCuri Medical Centre, Venlo, The Netherlands., Maas AFG; Department of Internal Medicine, VieCuri Medical Centre, Venlo, The Netherlands., Wyers CE; Department of Internal Medicine, VieCuri Medical Centre, Venlo, The Netherlands., Gach D; Department of Clinical Epidemiology, VieCuri Medical Centre, Venlo, The Netherlands.; Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands., Schols AMWJ; Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands., Beijers RJHCG; Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands., van den Bergh JP; Department of Internal Medicine, VieCuri Medical Centre, Venlo, The Netherlands.; Department of Internal Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands., van Osch FHM; Department of Clinical Epidemiology, VieCuri Medical Centre, Venlo, The Netherlands. fvosch@viecuri.nl.; Department of Epidemiology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University, Maastricht, The Netherlands. fvosch@viecuri.nl.
المصدر: Scientific reports [Sci Rep] 2023 Jan 13; Vol. 13 (1), pp. 681. Date of Electronic Publication: 2023 Jan 13.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : Nature Publishing Group, copyright 2011-
مواضيع طبية MeSH: COVID-19*/complications, Humans ; Cohort Studies ; Patient Discharge ; Lung ; Hospitals ; Follow-Up Studies
مستخلص: Some COVID-19 survivors suffer from persistent pulmonary function impairment, but the extent and associated factors are unclear. This study aimed to characterize pulmonary function impairment three to five months after hospital discharge and the association with disease severity. Survivors of COVID-19 after hospitalization to the VieCuri Medical Centre between February and December 2020 were invited for follow-up, three to five months after discharge. Dynamic and static lung volumes, respiratory muscle strength and diffusion capacity were measured. The cohort comprised 257 patients after a moderate (n = 33), severe (n = 151) or critical (n = 73) COVID-19 infection with a median follow-up of 112 days (interquartile range 96-134 days). The main sequelae included reduced diffusion capacity (36%) and reduced maximal expiratory pressure (24%). Critically ill patients were more likely to have reduced diffusion capacity than moderate (OR 8.00, 95% CI 2.46-26.01) and severe cases (OR 3.74, 95% CI 1.88-7.44) and lower forced vital capacity (OR 3.29, 95% CI 1.20-9.06) compared to severe cases. Many COVID-19 survivors, especially after a critical disease course, showed pulmonary function sequelae, mainly DLCO impairments, three to five months after discharge. Monitoring is needed to investigate the persistence of these symptoms and the longer-term implications of the COVID-19 burden.
(© 2023. The Author(s).)
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تواريخ الأحداث: Date Created: 20230113 Date Completed: 20230117 Latest Revision: 20230328
رمز التحديث: 20230328
مُعرف محوري في PubMed: PMC9839688
DOI: 10.1038/s41598-023-27879-8
PMID: 36639404
قاعدة البيانات: MEDLINE
الوصف
تدمد:2045-2322
DOI:10.1038/s41598-023-27879-8