دورية أكاديمية

Determinant factors of bone health after long-term of Roux-en-Y gastric bypass surgery: A cross-sectional study.

التفاصيل البيبلوغرافية
العنوان: Determinant factors of bone health after long-term of Roux-en-Y gastric bypass surgery: A cross-sectional study.
المؤلفون: Araújo MM; Graduate Program in Human Nutrition, University of Brasília, Brasília, Brazil., Mendes MM; Graduate Program in Human Nutrition, University of Brasília, Brasília, Brazil., Costa LM; Graduate Program in Human Nutrition, University of Brasília, Brasília, Brazil., Lima RM; Graduate Program in Human Nutrition, University of Brasília, Brasília, Brazil; Graduate Program in Physical Education, University of Brasília, Brasília, Brazil., Lanham-New SA; Department of Nutritional Sciences, School of Biosciences and Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK., Baiocchi de Carvalho KM; Graduate Program in Human Nutrition, University of Brasília, Brasília, Brazil., Botelho PB; Graduate Program in Human Nutrition, University of Brasília, Brasília, Brazil. Electronic address: patriciabotelho@unb.br.
المصدر: Nutrition (Burbank, Los Angeles County, Calif.) [Nutrition] 2023 Apr; Vol. 108, pp. 111937. Date of Electronic Publication: 2022 Dec 13.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8802712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-1244 (Electronic) Linking ISSN: 08999007 NLM ISO Abbreviation: Nutrition Subsets: MEDLINE
أسماء مطبوعة: Publication: Tarrytown, NY : Elsevier Science
Original Publication: [Burbank, Calif. : Nutrition, c1987-
مواضيع طبية MeSH: Gastric Bypass* , Obesity, Morbid*/surgery, Adult ; Humans ; Female ; Male ; Bone Density ; Cross-Sectional Studies ; Bone and Bones/metabolism ; Vitamin D
مستخلص: Objectives: The aim of this study was to evaluate bone health and the potential influencing factors of bone metabolism disorders in adults ≥5 y after Roux-en-Y gastric bypass (RYGB) surgery.
Methods: In this cross-sectional study, patients who were ≥5 y post-RYGB were invited. Bone health considered as bone mineral content (BMC) and bone mineral density (BMD) in this study was assessed by dual x-ray absorptiometry. We also assessed 25-hydroxy-vitamin D concentrations, individual ultraviolet B radiation levels, serum ionized calcium, alkaline phosphatase, parathyroid, anthropometric, and body composition.
Results: The study evaluated 104 adults (90% women; 49.6 ± 9.1 y old; postoperative period 8.7 ± 2.2 y). Lumbar and femoral BMC and BMD were positively correlated to body mass index (BMI), appendicular lean mass (ALM), and negatively to %excess of weight loss (EWL). Femoral BMD was negatively correlated to age, and both femoral BMD and BMC were positively correlated to weekly exposed body part score. Sex, age, BMI, ALM, and weekly exposed body part score explained 35% and 54% of the total variance of femoral BMD and BMC, respectively.
Conclusions: The present findings suggested that older age, lower BMI, higher %EWL, lower ALM, and lower weekly body part exposure score are important determinants in lowering BMD and BMC parameters in long-term post-bariatric surgery individuals, rather than serum 25-hydroxy-vitamin D and parathyroid.
(Copyright © 2022 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: 25-hydroxy-vitamin D; Bariatric surgery; Bone health; Roux-en-Y gastric bypass; Sun exposure; Vitamin D
المشرفين على المادة: 1406-16-2 (Vitamin D)
تواريخ الأحداث: Date Created: 20230114 Date Completed: 20230307 Latest Revision: 20230627
رمز التحديث: 20240628
DOI: 10.1016/j.nut.2022.111937
PMID: 36640632
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-1244
DOI:10.1016/j.nut.2022.111937