دورية أكاديمية
أعرض في EDS

Effect of TNF inhibitors on arterial stiffness and intima media thickness in rheumatoid arthritis: a systematic review and meta-analysis.

التفاصيل البيبلوغرافية
العنوان: Effect of TNF inhibitors on arterial stiffness and intima media thickness in rheumatoid arthritis: a systematic review and meta-analysis.
المؤلفون: Abdulmajid B; Department of Rheumatology, Amsterdam Rheumatology and Immunology Center, Location Reade, Amsterdam Dr. Jan van Breemenstraat 2, PO Box 58271, 1040 HG, Amsterdam, The Netherlands. bafrinam@hotmail.com.; Amsterdam UMC, Location AMC, Amsterdam, The Netherlands. bafrinam@hotmail.com., Blanken AB; Department of Rheumatology, Amsterdam Rheumatology and Immunology Center, Location Reade, Amsterdam Dr. Jan van Breemenstraat 2, PO Box 58271, 1040 HG, Amsterdam, The Netherlands.; Department of Rheumatology, Amsterdam Rheumatology and Immunology Center, Location Amsterdam UMC, VU University Medical Center, Amsterdam, The Netherlands.; Department of Medical Library, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands., van Geel EH; Department of Rheumatology, Amsterdam Rheumatology and Immunology Center, Location Reade, Amsterdam Dr. Jan van Breemenstraat 2, PO Box 58271, 1040 HG, Amsterdam, The Netherlands.; Department of Rheumatology, Amsterdam Rheumatology and Immunology Center, Location Amsterdam UMC, VU University Medical Center, Amsterdam, The Netherlands., Daams JG; Department of Medical Library, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands., Nurmohamed MT; Department of Rheumatology, Amsterdam Rheumatology and Immunology Center, Location Reade, Amsterdam Dr. Jan van Breemenstraat 2, PO Box 58271, 1040 HG, Amsterdam, The Netherlands.; Department of Rheumatology, Amsterdam Rheumatology and Immunology Center, Location Amsterdam UMC, VU University Medical Center, Amsterdam, The Netherlands.; Department of Medical Library, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands.
المصدر: Clinical rheumatology [Clin Rheumatol] 2023 Apr; Vol. 42 (4), pp. 999-1011. Date of Electronic Publication: 2023 Jan 16.
نوع المنشور: Meta-Analysis; Systematic Review; Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 8211469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1434-9949 (Electronic) Linking ISSN: 07703198 NLM ISO Abbreviation: Clin Rheumatol Subsets: MEDLINE
أسماء مطبوعة: Publication: <2008->: Heidelberg : Springer
Original Publication: Brussels : Acta Medica Belgica, [1982-
مواضيع طبية MeSH: Arthritis, Rheumatoid*/complications , Arthritis, Rheumatoid*/drug therapy , Arthritis, Rheumatoid*/pathology , Tumor Necrosis Factor Inhibitors*/therapeutic use , Vascular Stiffness*/drug effects, Humans ; Carotid Intima-Media Thickness ; Prospective Studies ; Pulse Wave Analysis/methods ; Risk Factors
مستخلص: Controlling inflammation with tumor necrosis factor (TNF) inhibitors in rheumatoid arthritis (RA) patients is hypothesized to reduce their cardiovascular risk. We performed a systematic review and meta-analysis on the effects of TNF inhibitors on arterial stiffness and carotid intima media thickness (IMT) in RA. MEDLINE, EMBASE, clinicaltrials.gov , and WHO Clinical Trials Registry were searched up to September 2021 for randomized controlled trials, prospective cohort studies, and nonrandomized clinical trials evaluating the effects of TNF inhibitors on pulse wave velocity (PWV), augmentation index (AIx), and IMT in RA. A meta-analysis was performed to assess changes of these measures after therapy during different follow-up periods. Risk of bias assessment was performed using an adjusted Downs and Black checklist (INPLASY: 2022-1-0131). Thirty studies were identified from 1436 records, of which 23 were included in the meta-analysis. PWV and AIx showed a decrease after treatment (PWV: mean difference (MD) -0.51 m/s (95% CI: -0.96, -0.06), p=0.027; AIx: MD -0.57% (95% CI: -2.11, 0.96), p=0.463, sensitivity analysis AIx: MD -1.21% (95% CI: -2.60, 0.19), p=0.089). For IMT, there was a slight increase in the first months of follow-up, but this disappeared on the long-term (overall timepoints MD -0.01 mm (95% CI: -0.04, 0.02), p=0.615). Heterogeneity was high in the overall analyses and subgroups with long follow-up periods (≥12 months). The included studies showed mixed results of the effects of TNF inhibitors on the surrogate markers. The pooled results suggest that PWV and AIx decrease over time, while IMT remains stable. This indicates a favorable effect of TNF inhibitors on the cardiovascular disease risk, all the more since these markers also increase with age.
(© 2023. The Author(s).)
References: Nihon Rinsho Meneki Gakkai Kaishi. 2012;35(3):183-7. (PMID: 22790578)
Scand J Rheumatol. 2009 Jan-Feb;38(1):6-10. (PMID: 18991190)
Curr Ther Res Clin Exp. 2018 Jul 23;89:1-6. (PMID: 30128057)
Rheumatology (Oxford). 2014 Jun;53(6):1108-19. (PMID: 24501245)
Atherosclerosis. 2013 Dec;231(2):436-41. (PMID: 24267263)
Clin Rheumatol. 2018 Feb;37(2):515-526. (PMID: 28484887)
Rheumatol Int. 2020 Mar;40(3):427-436. (PMID: 31848735)
Heart. 2016 May 15;102(10):790-5. (PMID: 26888573)
Rheumatol Int. 2009 Dec;30(2):193-8. (PMID: 19387646)
Arthritis Rheum. 2006 Feb 15;55(1):150-3. (PMID: 16463428)
Cardiovasc Ther. 2010 Oct;28(5):e53-64. (PMID: 20337633)
Atherosclerosis. 2006 Jul;187(1):110-5. (PMID: 16168418)
Br J Clin Pharmacol. 2005 May;59(5):491-4. (PMID: 15842546)
J Immunol Res. 2015;2015:759610. (PMID: 26090499)
Semin Arthritis Rheum. 2008 Aug;38(1):13-9. (PMID: 18191989)
J Rheumatol. 2012 Dec;39(12):2267-75. (PMID: 22984272)
Blood Press. 2004;13(6):369-75. (PMID: 15771222)
Rheumatology (Oxford). 2005 Nov;44(11):1428-32. (PMID: 16076882)
Expert Opin Pharmacother. 2008 May;9(7):1121-8. (PMID: 18422470)
Arthritis Care Res (Hoboken). 2011 Apr;63(4):522-9. (PMID: 20957658)
Circulation. 2012 Nov 20;126(21):2473-80. (PMID: 23095282)
J Clin Rheumatol. 2014 Jan;20(1):1-10. (PMID: 24356481)
Mod Rheumatol. 2007;17(5):385-90. (PMID: 17929130)
BMJ. 2021 Mar 29;372:n71. (PMID: 33782057)
Clin Rheumatol. 2015 Feb;34(2):359-64. (PMID: 24928345)
Circulation. 2006 Sep 12;114(11):1185-92. (PMID: 16952987)
Curr Med Res Opin. 2006 Nov;22(11):2181-90. (PMID: 17076979)
Isr Med Assoc J. 2011 Mar;13(3):147-52. (PMID: 21608334)
Circulation. 2006 Jun 27;113(25):2936-42. (PMID: 16801474)
Ann Rheum Dis. 2009 Aug;68(8):1277-84. (PMID: 18930987)
J Comorb. 2019 Jun 03;9:2235042X19853484. (PMID: 31211114)
Rheumatology (Oxford). 2009 Nov;48(11):1418-23. (PMID: 19734293)
Rheumatology (Oxford). 2007 Jul;46(7):1111-5. (PMID: 17449484)
Semin Arthritis Rheum. 2011 Apr;40(5):389-97. (PMID: 20889191)
Arthritis Rheum. 2001 Dec;44(12):2737-45. (PMID: 11762933)
Am J Cardiol. 2011 Nov 1;108(9):1362-70. (PMID: 21855836)
Can J Cardiol. 2004 Sep;20(11):1097-100. (PMID: 15457305)
Joint Bone Spine. 2011 Mar;78(2):179-83. (PMID: 20851020)
Int J Gen Med. 2009 Jul 30;2:141-4. (PMID: 20360897)
Clin Rheumatol. 2010 Jul;29(7):723-7. (PMID: 20162315)
Ann Rheum Dis. 2008 Jan;67(1):64-9. (PMID: 17517756)
J Ultrasound Med. 2010 Dec;29(12):1759-68. (PMID: 21098848)
J Clin Hypertens (Greenwich). 2018 Feb;20(2):258-265. (PMID: 29267992)
J Rheumatol. 2007 Dec;34(12):2388-94. (PMID: 18050386)
Arthritis Care Res (Hoboken). 2018 Dec;70(12):1748-1755. (PMID: 29512334)
Ann Rheum Dis. 2013 Jun;72(6):881-7. (PMID: 22872022)
Syst Rev. 2016 Dec 5;5(1):210. (PMID: 27919275)
Arthritis Care Res (Hoboken). 2016 Apr;68(4):415-23. (PMID: 26315715)
Lancet. 2012 Jun 2;379(9831):2053-62. (PMID: 22541275)
Stroke. 2004 Sep;35(9):2150-4. (PMID: 15243147)
J Korean Med Sci. 2015 Nov;30(11):1589-96. (PMID: 26539002)
J Cardiovasc Magn Reson. 2021 Apr 19;23(1):46. (PMID: 33866975)
BMJ. 2018 Apr 23;361:k1036. (PMID: 29685876)
Semin Arthritis Rheum. 2012 Aug;42(1):1-8. (PMID: 22475245)
Best Pract Res Clin Rheumatol. 2007 Oct;21(5):871-83. (PMID: 17870033)
J Rheumatol. 2011 Oct;38(10):2169-71. (PMID: 21807781)
Mediators Inflamm. 2012;2012:674265. (PMID: 22899879)
Br J Clin Pharmacol. 2020 May;86(5):837-851. (PMID: 31957052)
J Atheroscler Thromb. 2012;19(9):872-80. (PMID: 22972311)
فهرسة مساهمة: Keywords: Cardiovascular burden; Rheumatoid arthritis; Systematic review; Tumor necrosis factor inhibitors
المشرفين على المادة: 0 (Tumor Necrosis Factor Inhibitors)
تواريخ الأحداث: Date Created: 20230116 Date Completed: 20230330 Latest Revision: 20230330
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10017587
DOI: 10.1007/s10067-023-06505-y
PMID: 36645550
قاعدة البيانات: MEDLINE
الوصف
تدمد:1434-9949
DOI:10.1007/s10067-023-06505-y