دورية أكاديمية
Wound healing and antibacterial capability of electrospun polyurethane nanofibers incorporating Calendula officinalis and Propolis extracts.
| العنوان: | Wound healing and antibacterial capability of electrospun polyurethane nanofibers incorporating Calendula officinalis and Propolis extracts. |
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| المؤلفون: | Davoudabadi M; Molecular and Medicine Research Center, Arak University of Medical Science, Arak, Iran., Fahimirad S; Molecular and Medicine Research Center, Arak University of Medical Science, Arak, Iran., Ganji A; Molecular and Medicine Research Center, Arak University of Medical Science, Arak, Iran.; Department of Microbiology and Immunology, School of Medicine, Arak University of Medical Sciences, Arak, Iran., Abtahi H; Molecular and Medicine Research Center, Arak University of Medical Science, Arak, Iran. |
| المصدر: | Journal of biomaterials science. Polymer edition [J Biomater Sci Polym Ed] 2023 Aug; Vol. 34 (11), pp. 1491-1516. Date of Electronic Publication: 2023 Feb 01. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor and Francis Country of Publication: England NLM ID: 9007393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1568-5624 (Electronic) Linking ISSN: 09205063 NLM ISO Abbreviation: J Biomater Sci Polym Ed Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2012- : Abingdon, Oxon : Taylor and Francis Original Publication: Utrecht, The Netherlands : VSP, c1989- |
| مواضيع طبية MeSH: | Propolis*/pharmacology , Propolis*/chemistry , Nanofibers*/chemistry , Calendula* , Methicillin-Resistant Staphylococcus aureus*, Polyurethanes/chemistry ; Antioxidants ; Wound Healing ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry |
| مستخلص: | In order to produce a healing accelerator antibacterial wound dressing, different electrospun polyurethane (PU)-based nanofibers inclusive Calendula officinalis and Propolis ethanolic extracts were fabricated. The measurement of minimum inhibitory concentrations (MIC) against Methicillin-resistant Staphylococcus aureus (MRSA) determined the concentrations of incorporating extracts. Then the morphological properties of the produced polyurethane (PU), polyurethane/ C. officinalis (PU/CO), polyurethane/Propolis (PU/PR), polyurethane/ C. officinalis /Propolis (PU/CO/PR) were analyzed by scanning electron microscopy (SEM). The physicochemical features and biological characteristics of the fabricated nanofibers were evaluated. Subsequently, the antibacterial and wound-healing efficiency of electrospun wound dressings were tested under in vivo situation. The electrospun PU/CO/PR nanofiber illustrated the most degree of antibacterial, antioxidant, and cell proliferation efficiencies. In vivo examination and histological analysis confirmed significant improvement in the complete, well-organized wound-healing process in MRSA-infected wounds treated with PU/CO/PR. These outcomes described PU/CO/PR electrospun nanofibers as a wound dressing that can significantly facilitate wound healing with notable antibacterial, antioxidant, and cell proliferation properties. |
| فهرسة مساهمة: | Keywords: Calendula officinalis; Electrospinning; Propolis extracts; antimicrobial; nanofiber; polyurethane |
| المشرفين على المادة: | 9009-62-5 (Propolis) 0 (Polyurethanes) 0 (Antioxidants) 0 (Anti-Bacterial Agents) |
| تواريخ الأحداث: | Date Created: 20230117 Date Completed: 20230731 Latest Revision: 20230731 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1080/09205063.2023.2170138 |
| PMID: | 36648427 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1568-5624 |
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| DOI: | 10.1080/09205063.2023.2170138 |