دورية أكاديمية
أعرض في EDS

Interphase chromosomes of the Aedes aegypti mosquito are liquid crystalline and can sense mechanical cues.

التفاصيل البيبلوغرافية
العنوان: Interphase chromosomes of the Aedes aegypti mosquito are liquid crystalline and can sense mechanical cues.
المؤلفون: Contessoto VG; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA. vinicius.contessoto@rice.edu.; Instituto de Biociências, Letras e Ciências Exatas, UNESP - Univ. Estadual Paulista, Departamento de Física, São José do Rio Preto, SP, Brazil. vinicius.contessoto@rice.edu., Dudchenko O; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA.; The Center for Genome Architecture, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Aiden EL; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA.; The Center for Genome Architecture, Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Wolynes PG; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA.; Department of Physics & Astronomy, Rice University, Houston, TX, USA.; Department of Chemistry, Rice University, Houston, TX, USA.; Department of Biosciences, Rice University, Houston, TX, USA., Onuchic JN; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA. jonuchic@rice.edu.; Department of Physics & Astronomy, Rice University, Houston, TX, USA. jonuchic@rice.edu.; Department of Chemistry, Rice University, Houston, TX, USA. jonuchic@rice.edu.; Department of Biosciences, Rice University, Houston, TX, USA. jonuchic@rice.edu., Di Pierro M; Department of Physics, Northeastern University, Boston, MA, USA. dipierro@northeastern.edu.; Center for Theoretical Biological Physics, Northeastern University, Boston, MA, USA. dipierro@northeastern.edu.
المصدر: Nature communications [Nat Commun] 2023 Jan 19; Vol. 14 (1), pp. 326. Date of Electronic Publication: 2023 Jan 19.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
اللغة: English
بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : Nature Pub. Group
مواضيع طبية MeSH: Aedes*/genetics, Animals ; Cues ; Telomere/genetics ; Chromosome Structures ; Interphase
مستخلص: We use data-driven physical simulations to study the three-dimensional architecture of the Aedes aegypti genome. Hi-C maps exhibit both a broad diagonal and compartmentalization with telomeres and centromeres clustering together. Physical modeling reveals that these observations correspond to an ensemble of 3D chromosomal structures that are folded over and partially condensed. Clustering of the centromeres and telomeres near the nuclear lamina appears to be a necessary condition for the formation of the observed structures. Further analysis of the mechanical properties of the genome reveals that the chromosomes of Aedes aegypti, by virtue of their atypical structural organization, are highly sensitive to the deformation of the nuclei. This last finding provides a possible physical mechanism linking mechanical cues to gene regulation.
(© 2023. The Author(s).)
References: Sci Rep. 2019 May 1;9(1):6795. (PMID: 31043625)
Cell. 2012 Mar 2;148(5):908-21. (PMID: 22341456)
Elife. 2020 Oct 13;9:. (PMID: 33047670)
Nature. 2017 Nov 2;551(7678):51-56. (PMID: 29094699)
Elife. 2016 May 18;5:. (PMID: 27192037)
Science. 2021 May 28;372(6545):984-989. (PMID: 34045355)
Science. 2009 Oct 9;326(5950):289-93. (PMID: 19815776)
J Exp Bot. 2015 Nov;66(21):6623-34. (PMID: 26208647)
Nat Rev Mol Cell Biol. 2021 Aug;22(8):511-528. (PMID: 33953379)
Nucleic Acids Res. 2021 Jan 8;49(D1):D172-D182. (PMID: 33021634)
Cell. 2017 Oct 5;171(2):305-320.e24. (PMID: 28985562)
Curr Opin Struct Biol. 2022 Aug;75:102418. (PMID: 35839701)
Science. 2018 Feb 9;359(6376):. (PMID: 29348367)
Cell. 2018 May 17;173(5):1165-1178.e20. (PMID: 29706548)
Nat Genet. 2006 Nov;38(11):1348-54. (PMID: 17033623)
Science. 2007 Jun 22;316(5832):1718-23. (PMID: 17510324)
BMC Biol. 2019 Dec 30;17(1):108. (PMID: 31884969)
J Mol Graph. 1996 Feb;14(1):33-8, 27-8. (PMID: 8744570)
J Microsc. 2004 May;214(Pt 2):201-6. (PMID: 15102067)
PLoS Negl Trop Dis. 2021 Jun 3;15(6):e0009418. (PMID: 34081717)
J Comput Chem. 2004 Oct;25(13):1605-12. (PMID: 15264254)
Nature. 2016 Jan 7;529(7584):110-4. (PMID: 26700815)
Cell. 2014 Dec 18;159(7):1665-80. (PMID: 25497547)
Science. 2017 Apr 7;356(6333):92-95. (PMID: 28336562)
Cell Syst. 2016 Jul;3(1):95-8. (PMID: 27467249)
Nat Commun. 2017 May 19;8:15412. (PMID: 28524874)
PLoS Comput Biol. 2019 Jun 10;15(6):e1007024. (PMID: 31181064)
PLoS One. 2020 Jan 28;15(1):e0222900. (PMID: 31990920)
J Infect Public Health. 2016 Sep-Oct;9(5):684-6. (PMID: 26754201)
Nat Commun. 2022 Apr 12;13(1):1960. (PMID: 35413948)
Nature. 2016 Oct 13;538(7624):265-269. (PMID: 27706140)
Cell Rep. 2016 May 31;15(9):2038-49. (PMID: 27210764)
Nat Genet. 2017 Jan;49(1):65-74. (PMID: 27869826)
Sci Rep. 2016 Jul 13;6:29775. (PMID: 27405443)
Genome Biol. 2016 Mar 31;17:59. (PMID: 27036497)
Nature. 2019 Jun;570(7761):395-399. (PMID: 31168090)
Cell Rep. 2020 Feb 18;30(7):2125-2135.e5. (PMID: 32075757)
Cell Rep. 2022 Mar 29;38(13):110601. (PMID: 35354035)
Cell. 2015 May 21;161(5):1012-1025. (PMID: 25959774)
Cell. 2018 Jul 12;174(2):363-376.e16. (PMID: 29887381)
Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6456-65. (PMID: 26499245)
J Cell Sci. 2001 Jul;114(Pt 13):2427-35. (PMID: 11559751)
EMBO J. 2017 Dec 15;36(24):3573-3599. (PMID: 29217591)
Am J Trop Med Hyg. 2006 Nov;75(5):886-92. (PMID: 17123982)
Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):12739-12744. (PMID: 30478042)
BMC Biol. 2021 Mar 19;19(1):53. (PMID: 33740972)
Gigascience. 2021 Feb 16;10(2):. (PMID: 33590861)
Science. 2016 Mar 25;351(6280):1454-1458. (PMID: 26940867)
Bioinformatics. 2012 Aug 15;28(16):2193-4. (PMID: 22730430)
Microorganisms. 2019 Jan 22;7(2):. (PMID: 30678153)
Cell. 2017 May 18;169(5):930-944.e22. (PMID: 28525758)
J Mol Biol. 2021 Mar 19;433(6):166700. (PMID: 33160979)
Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12168-12173. (PMID: 27688758)
Mol Cell. 2012 Nov 9;48(3):471-84. (PMID: 23041285)
Nat Rev Genet. 2001 Apr;2(4):292-301. (PMID: 11283701)
Curr Opin Genet Dev. 2016 Apr;37:36-45. (PMID: 26826680)
Cell Syst. 2016 Jul;3(1):99-101. (PMID: 27467250)
Annu Rev Genomics Hum Genet. 2013;14:67-84. (PMID: 23875797)
Nature. 2012 Apr 11;485(7398):381-5. (PMID: 22495304)
Trends Genet. 2016 Apr;32(4):225-237. (PMID: 26862051)
Nature. 2018 Nov;563(7732):501-507. (PMID: 30429615)
Nat Methods. 2013 Dec;10(12):1213-8. (PMID: 24097267)
Phys Rev Lett. 2016 Jun 17;116(24):248101. (PMID: 27367409)
Genome Biol. 2008;9(9):R137. (PMID: 18798982)
Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12126-12131. (PMID: 29087948)
Elife. 2021 Jun 08;10:. (PMID: 34100718)
Nat Methods. 2012 Mar 04;9(4):357-9. (PMID: 22388286)
Nat Commun. 2018 Aug 8;9(1):3161. (PMID: 30089831)
J Phys Chem B. 2021 Aug 12;125(31):8757-8767. (PMID: 34319725)
Nucleic Acids Res. 2022 May 6;50(8):4258-4271. (PMID: 35420130)
Nat Genet. 2020 Jan;52(1):8-16. (PMID: 31925403)
Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6697-E6706. (PMID: 29967174)
Genome Res. 2006 Oct;16(10):1299-309. (PMID: 16954542)
PLoS Negl Trop Dis. 2013;7(2):e2052. (PMID: 23459230)
Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):7753-7758. (PMID: 29987017)
Sci Rep. 2019 Feb 28;9(1):3072. (PMID: 30816125)
Proc Natl Acad Sci U S A. 2015 May 12;112(19):6062-7. (PMID: 25918364)
Mem Inst Oswaldo Cruz. 2002 Apr;97(3):437-9. (PMID: 12048581)
Nucleus. 2013 May-Jun;4(3):176-81. (PMID: 23669133)
Plant Physiol. 2001 Feb;125(2):532-8. (PMID: 11161011)
Science. 2018 Apr 6;360(6384):102-105. (PMID: 29472443)
Nucleic Acids Res. 2012 Dec;40(22):11202-12. (PMID: 23074191)
Nature. 2012 Apr 11;485(7398):376-80. (PMID: 22495300)
Science. 2002 Feb 15;295(5558):1306-11. (PMID: 11847345)
Nat Genet. 2006 Nov;38(11):1341-7. (PMID: 17033624)
Nat Commun. 2019 Oct 3;10(1):4485. (PMID: 31582763)
Cell. 2020 Sep 17;182(6):1641-1659.e26. (PMID: 32822575)
Biophys J. 2020 May 5;118(9):2193-2208. (PMID: 32389215)
Biophys J. 2020 Nov 3;119(9):1905-1916. (PMID: 33086041)
Science. 2013 Nov 22;342(6161):948-53. (PMID: 24200812)
Mol Cell. 2019 Apr 4;74(1):212-222.e5. (PMID: 30795893)
Curr Biol. 1999 Nov 4;9(21):1263-6. (PMID: 10556096)
Cell. 2012 Feb 3;148(3):458-72. (PMID: 22265598)
معلومات مُعتمدة: R35 GM146852 United States GM NIGMS NIH HHS; UM1 HG009375 United States HG NHGRI NIH HHS; RM1 HG011016 United States HG NHGRI NIH HHS
تواريخ الأحداث: Date Created: 20230119 Date Completed: 20230123 Latest Revision: 20230601
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC9852290
DOI: 10.1038/s41467-023-35909-2
PMID: 36658127
قاعدة البيانات: MEDLINE
الوصف
تدمد:2041-1723
DOI:10.1038/s41467-023-35909-2