دورية أكاديمية

Recurrent implantation failure: A comprehensive summary from etiology to treatment.

التفاصيل البيبلوغرافية
العنوان: Recurrent implantation failure: A comprehensive summary from etiology to treatment.
المؤلفون: Ma J; Center of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, China.; Key Laboratory of Reproductive and Genetic Medicine, China Medical University, National Health Commission, Shenyang, China.; Shengjing Hospital of China Medical University, Key Laboratory of Reproductive Dysfunction Diseases and Fertility Remodeling of Liaoning Province, Shenyang, China., Gao W; Department of Obstetrics, the First Affiliated Hospital of China Medical University, Shenyang, China., Li D; Center of Reproductive Medicine, Shengjing Hospital of China Medical University, Shenyang, China.; Key Laboratory of Reproductive and Genetic Medicine, China Medical University, National Health Commission, Shenyang, China.; Shengjing Hospital of China Medical University, Key Laboratory of Reproductive Dysfunction Diseases and Fertility Remodeling of Liaoning Province, Shenyang, China.
المصدر: Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2023 Jan 05; Vol. 13, pp. 1061766. Date of Electronic Publication: 2023 Jan 05 (Print Publication: 2022).
نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101555782 Publication Model: eCollection Cited Medium: Print ISSN: 1664-2392 (Print) Linking ISSN: 16642392 NLM ISO Abbreviation: Front Endocrinol (Lausanne) Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Lausanne : Frontiers Research Foundation]
مواضيع طبية MeSH: Embryo Implantation* , Embryo Transfer*/methods, Pregnancy ; Female ; Male ; Humans ; Fertilization in Vitro/methods ; Endometrium ; Causality
مستخلص: Implantation is the first step in human reproduction. Successful implantation depends on the crosstalk between embryo and endometrium. Recurrent implantation failure (RIF) is a clinical phenomenon characterized by a lack of implantation after the transfer of several embryos and disturbs approximately 10% couples undergoing in vitro fertilization and embryo transfer. Despite increasing literature on RIF, there is still no widely accepted definition or standard protocol for the diagnosis and treatment of RIF. Progress in predicting and preventing RIF has been hampered by a lack of widely accepted definitions. Most couples with RIF can become pregnant after clinical intervention. The prognosis for couples with RIF is related to maternal age. RIF can be caused by immunology, thrombophilias, endometrial receptivity, microbiome, anatomical abnormalities, male factors, and embryo aneuploidy. It is important to determine the most possible etiologies, and individualized treatment aimed at the primary cause seems to be an effective method for increasing the implantation rate. Couples with RIF require psychological support and appropriate clinical intervention. Further studies are required to evaluate diagnostic method and he effectiveness of each therapy, and guide clinical treatment.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2023 Ma, Gao and Li.)
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فهرسة مساهمة: Keywords: anatomical abnormalities; aneuploidy; endometrial receptivity; immunology; microbiome; recurrent implantation failure; thrombophilias
تواريخ الأحداث: Date Created: 20230123 Date Completed: 20230124 Latest Revision: 20240226
رمز التحديث: 20240227
مُعرف محوري في PubMed: PMC9849692
DOI: 10.3389/fendo.2022.1061766
PMID: 36686483
قاعدة البيانات: MEDLINE
الوصف
تدمد:1664-2392
DOI:10.3389/fendo.2022.1061766