دورية أكاديمية
Adiponectin - stratification biomarker in diastolic cardiac dysfunction.
العنوان: | Adiponectin - stratification biomarker in diastolic cardiac dysfunction. |
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المؤلفون: | Dincă VG; Faculty of Medicine, Titu Maiorescu University Bucharest, Bucharest, Romania.; CF2 Clinical Hospital Bucharest, Romania., Diaconu A; Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.; Fundeni Clinical Institute, Bucharest, Romania., Coculescu BI; Faculty of Midwifery and Nursing, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.; Cantacuzino National Medico-Military Institute for Research and Development, Bucharest, Romania., Dincă AL; Faculty of Medicine, Titu Maiorescu University Bucharest, Bucharest, Romania.; CF2 Clinical Hospital Bucharest, Romania., Ciuc DM; Faculty of Medicine, Titu Maiorescu University Bucharest, Bucharest, Romania.; CF2 Clinical Hospital Bucharest, Romania., Bîrlă RD; Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.; Sf. Maria Clinical Hospital, Bucharest, Romania., Marica CD; Faculty of Medicine, Titu Maiorescu University Bucharest, Bucharest, Romania.; CF2 Clinical Hospital Bucharest, Romania., Tudorache SI; Faculty of Medicine, Titu Maiorescu University Bucharest, Bucharest, Romania., Manole G; Faculty of General Nursing, Bioterra University, Bucharest, Romania.; Romanian Academy of Medical Sciences., Coculescu EC; Faculty of Dental Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. |
المصدر: | Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2171030. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374 (Electronic) Linking ISSN: 14756366 NLM ISO Abbreviation: J Enzyme Inhib Med Chem Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Basingstoke, UK : Taylor & Francis, c2002- |
مواضيع طبية MeSH: | Heart Diseases* , Myocardial Ischemia*, Humans ; Adiponectin ; Biomarkers ; Echocardiography |
مستخلص: | This study does not propose to elucidate how adiponectin secretion is regulated, but how its adiponectin concentration is an indicator of heart disease. About adiponectin, it is not known whether it is functionally an enzyme, or very likely a cytokine/chemokine/hormone, secreted by fat cells/adipocytes in the abdomen. Abdominal fat secretes 67 hormones, and all of which cause disease. For example, adiponectin generates diabetes and ischaemic heart disease via dyslipidemia. Based on clinical symptoms, electrocardiographic and echocardiographic parameters, a group of 208 patients with diastolic cardiac dysfunction with or without preserved systolic function, developed on a background of painful chronic ischaemic heart disease, stable angina on exertion, was constituted. The serum levels of adiponectin, total cholesterol, LDL cholesterol, HDL cholesterol and triglycerides were measured. Using the identified values, it was appreciated whether adiponectin correlates with the type of any of the two conditions, so that it can be recognised as a diagnostic and risk stratification marker. |
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فهرسة مساهمة: | Keywords: Adiponectin; biomarker; coronary artery disease (CAD); diastolic dysfunction (DD); left ventricular ejection fraction (LVEF); preserved systolic function (PRESYF) |
المشرفين على المادة: | 0 (Adiponectin) 0 (Biomarkers) 0 (ADIPOQ protein, human) |
تواريخ الأحداث: | Date Created: 20230124 Date Completed: 20230130 Latest Revision: 20230202 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC9879170 |
DOI: | 10.1080/14756366.2023.2171030 |
PMID: | 36691932 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1475-6374 |
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DOI: | 10.1080/14756366.2023.2171030 |