دورية أكاديمية
Grape Seed Components as Protectors of Inflammation, DNA Damage, and Cancer.
| العنوان: | Grape Seed Components as Protectors of Inflammation, DNA Damage, and Cancer. |
|---|---|
| المؤلفون: | Mancini M; Cytogenetics and Genome Stability Laboratory, University Hospital and Pharmacy Postgraduate Program, Federal University of Santa Catarina, Florianópolis, Brazil., Cerny MEV; Cytogenetics and Genome Stability Laboratory, University Hospital and Pharmacy Postgraduate Program, Federal University of Santa Catarina, Florianópolis, Brazil., Cardoso NS; Cytogenetics and Genome Stability Laboratory, University Hospital and Pharmacy Postgraduate Program, Federal University of Santa Catarina, Florianópolis, Brazil., Verissimo G; GESIELEVER, Scientific Consultancy, Loosdrecht, The Netherlands., Maluf SW; Cytogenetics and Genome Stability Laboratory, University Hospital and Pharmacy Postgraduate Program, Federal University of Santa Catarina, Florianópolis, Brazil. 0808swm@gmail.com. |
| المصدر: | Current nutrition reports [Curr Nutr Rep] 2023 Mar; Vol. 12 (1), pp. 141-150. Date of Electronic Publication: 2023 Jan 24. |
| نوع المنشور: | Journal Article; Review; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer US Country of Publication: United States NLM ID: 101587480 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-3311 (Electronic) Linking ISSN: 21613311 NLM ISO Abbreviation: Curr Nutr Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: New York : Springer US, 2012- |
| مواضيع طبية MeSH: | Vitis* , Grape Seed Extract*/pharmacology , Neoplasms*/prevention & control, Humans ; Free Radicals ; DNA Damage ; Polyphenols/pharmacology ; Inflammation |
| مستخلص: | Purpose of Review: Oxidative stress is related to the pathogenesis of several chronic diseases, including inflammatory processes. Free radicals excess increase not only oxidative stress but also genomic instability. Polyphenols are non-enzymatic antioxidants that act as a defense barrier against free radicals and non-radical oxidants. The purpose of this article was to review published articles relating dietary polyphenols contained in grape seed proanthocyanidin extracts with its potential for reversing DNA damage. Recent Findings: Proanthocyanidin components exert pleiotropic actions having several biological, biochemical, and significant pharmacological effects and showed the ability to reduce cytotoxicity and genotoxicity. Grape seed proanthocyanidin extracts showed the ability to reduce cytotoxicity and genotoxicity through the comet assay and the micronucleus technique. (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.) |
| فهرسة مساهمة: | Keywords: Cancer risk assessment; Comet assay; Cytokinesis-blocked micronucleus (CBMN); Genomic instability; Proanthocyanidins |
| المشرفين على المادة: | 0 (Grape Seed Extract) 0 (Free Radicals) 0 (Polyphenols) |
| تواريخ الأحداث: | Date Created: 20230124 Date Completed: 20230302 Latest Revision: 20230510 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1007/s13668-023-00460-5 |
| PMID: | 36692807 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 2161-3311 |
|---|---|
| DOI: | 10.1007/s13668-023-00460-5 |