دورية أكاديمية
Invariant inhibition to calculate prediction errors?
العنوان: | Invariant inhibition to calculate prediction errors? |
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المؤلفون: | Creed MC; Department of Anesthesiology, Washington University in St Louis, St Louis, MO, USA; Department of Psychiatry, Washington University in St Louis, St Louis, MO, USA; Department of Neuroscience, Washington University in St Louis, St Louis, MO, USA; Department of Biomedical Engineering, Washington University in St Louis, St Louis, MO, USA; Pain Center, Washington University in St Louis, St Louis, MO, USA., Loureiro M; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland., Lüscher C; Department of Basic Neurosciences, Medical Faculty, University of Geneva, CH-1211 Geneva, Switzerland; Clinic of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, CH-1211 Geneva, Switzerland. Electronic address: christian.luscher@unige.ch. |
المصدر: | Trends in neurosciences [Trends Neurosci] 2023 Apr; Vol. 46 (4), pp. 257-259. Date of Electronic Publication: 2023 Jan 26. |
نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Comment |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Applied Science Publishing Country of Publication: England NLM ID: 7808616 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-108X (Electronic) Linking ISSN: 01662236 NLM ISO Abbreviation: Trends Neurosci Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Barking : Elsevier Applied Science Publishing Original Publication: Amsterdam, New York, Elsevier/North-Holland Biomedical Press. |
مواضيع طبية MeSH: | Ventral Tegmental Area*/physiology , Basal Ganglia*, Humans ; Dopamine ; Reward |
مستخلص: | The ventral tegmental area (VTA) has a pivotal role in motivated behavior. Much of the research on the VTA has focused on the mesocorticolimbic dopamine projections and their role in the computation of a 'reward prediction error' (RPE) for reward-guided learning. In a recent study, Zhou et al. report that VTA GABA neurons, the axons of which innervate the ventral pallidum (VP), have a unique role in signaling reward value to the basal ganglia and guiding reward seeking. Competing Interests: Declaration of interests The authors declare no conflicts of interest in relation to this work. (Copyright © 2023 Elsevier Ltd. All rights reserved.) |
التعليقات: | Comment on: Sci Adv. 2022 Oct 21;8(42):eabm5217. (PMID: 36260661) |
معلومات مُعتمدة: | R01 DA049924 United States DA NIDA NIH HHS |
فهرسة مساهمة: | Keywords: GABA; dopamine; reward prediction error |
المشرفين على المادة: | VTD58H1Z2X (Dopamine) |
تواريخ الأحداث: | Date Created: 20230127 Date Completed: 20230324 Latest Revision: 20230410 |
رمز التحديث: | 20240628 |
DOI: | 10.1016/j.tins.2023.01.004 |
PMID: | 36707259 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1878-108X |
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DOI: | 10.1016/j.tins.2023.01.004 |