دورية أكاديمية
أعرض في EDS

Associations of an eye-tracking task and pupillary metrics with age and ASA physical status score in a preoperative cohort.

التفاصيل البيبلوغرافية
العنوان: Associations of an eye-tracking task and pupillary metrics with age and ASA physical status score in a preoperative cohort.
المؤلفون: Papangelou A; Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA, USA. apapang@emory.edu., Boorman DW; Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA, USA., Sharifpour M; Department of Anesthesiology, Cedars Sinai Medical Center, Los Angeles, CA, USA., Patel HP; Department of Internal Medicine, Wellstar Kennestone Regional Medical Center, Marietta, GA, USA., Cassim T; Department of Anesthesiology, Columbia University, New York, NY, USA., García PS; Department of Anesthesiology, Columbia University, New York, NY, USA.
المصدر: Journal of clinical monitoring and computing [J Clin Monit Comput] 2023 Jun; Vol. 37 (3), pp. 795-803. Date of Electronic Publication: 2023 Jan 28.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: Netherlands NLM ID: 9806357 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2614 (Electronic) Linking ISSN: 13871307 NLM ISO Abbreviation: J Clin Monit Comput Subsets: MEDLINE
أسماء مطبوعة: Publication: Amsterdam : Springer
Original Publication: Dordrecht, The Netherlands ; Boston : Kluwer Academic Publishers, c1998-
مواضيع طبية MeSH: Neurodegenerative Diseases* , Cognitive Dysfunction*, Humans ; Middle Aged ; Pupil ; Eye-Tracking Technology ; Prospective Studies
مستخلص: Advanced age, American Society of Anesthesiologists physical status (ASA) classification and the presence of cognitive impairment are associated with an elevated risk of postoperative morbidity and mortality. The visual paired comparison (VPC) task, which relies on recognition of novel images, examines declarative memory. VPC scores have demonstrated the ability to detect mild cognitive impairment and track progression of neurodegenerative disease. Quantitative pupillometry may have similar value. We evaluate for associations between these variables of interest and the feasibility of performing these tests in the preoperative clinic. Prospective data from 199 patients seen in the preoperative clinic at a tertiary academic center were analyzed. A 5 min VPC task (Neurotrack Technologies, Inc, Redwood City, CA) was administered during their scheduled preoperative clinic visit. Pupillary light reflexes were measured at the same visit (PLR-3000™, Neuroptics Corp, Irvine, California).Thirty-four percent of patients were categorized as ASA 2 and 58% as ASA 3. Median age was 57 (IQR: 44-69). Associations were demonstrated between age and ASA physical status (Mann-Whitney U Test, p < 0.0001), maximum pupil size (Spearman Rank Correlation, r = - 0.40, p < 0.0001), and maximum constriction velocity (Spearman Rank Correlation, r = - 0.39, p < 0.0001). Our data also revealed an association between VPC score and age (Spearman Rank Correlation, p = 0.0016, r = - 0.21) but not ASA score (Kruskal-Wallis Test, p = 0.14). When compared to a nonsurgical cohort with no history of memory impairment, our population scored worse on the VPC task (Mann-Whitney U Test, p = 0.0002). A preoperative 5 min VPC task and pupillometry are feasible tests in the preoperative setting and may provide a valuable window into an individual's cognition prior to elective surgery.
(© 2023. The Author(s), under exclusive licence to Springer Nature B.V.)
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معلومات مُعتمدة: 220020484 James S. McDonnell Foundation
فهرسة مساهمة: Keywords: Cognitive impairment; Maximum constriction velocity; Maximum pupil size; Preoperative; Pupillometer; Visual paired comparison task
تواريخ الأحداث: Date Created: 20230128 Date Completed: 20230515 Latest Revision: 20230523
رمز التحديث: 20230523
مُعرف محوري في PubMed: PMC9883606
DOI: 10.1007/s10877-023-00974-x
PMID: 36708440
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-2614
DOI:10.1007/s10877-023-00974-x