دورية أكاديمية
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Development and Validation of a Bedside Dengue Severity Score for Predicting Severe Dengue in Children.

التفاصيل البيبلوغرافية
العنوان: Development and Validation of a Bedside Dengue Severity Score for Predicting Severe Dengue in Children.
المؤلفون: Gayathri V; Institute of Child Health and Hospital for Children, Madras Medical College, Chennai, Tamil Nadu., Lakshmi SV; Institute of Child Health and Hospital for Children, Madras Medical College, Chennai, Tamil Nadu., Murugan SS; Institute of Child Health and Hospital for Children, Madras Medical College, Chennai, Tamil Nadu., Poovazhagi V; Institute of Child Health and Hospital for Children, Madras Medical College, Chennai, Tamil Nadu., Kalpana S; Institute of Child Health and Hospital for Children, Madras Medical College, Chennai, Tamil Nadu. Correspondence to: Dr Sivasambo Kalpana, No 1, Second Cross Street, 3rd Main Road, Nolambur Phase 1, Chennai 600 037, Tamil Nadu. drskalpana@yahoo.co.in.
المصدر: Indian pediatrics [Indian Pediatr] 2023 May 15; Vol. 60 (5), pp. 359-363. Date of Electronic Publication: 2023 Feb 09.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Indian Pediatrics Country of Publication: India NLM ID: 2985062R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0974-7559 (Electronic) Linking ISSN: 00196061 NLM ISO Abbreviation: Indian Pediatr Subsets: MEDLINE
أسماء مطبوعة: Publication: New Delhi : Indian Pediatrics
Original Publication: Bombay.
مواضيع طبية MeSH: Severe Dengue*/diagnosis , Severe Dengue*/epidemiology, Humans ; Child ; Predictive Value of Tests ; Hospitalization
مستخلص: Objective: To develop and validate a bedside dengue severity score in children less than 12 years for predicting severe dengue disease.
Methods: We carried out an analysis of data on the clinical and laboratory parameters of patients with confirmed dengue, hospitalized in October, 2019 at our center. A comprehensive patient's score was developed. Predictive models for severity were built using a forward step-wise method. This model was validated on the data of 312 children with dengue admitted during September- October, 2021.
Results: Severe dengue was predicted by the dengue severity score with a sensitivity of 86.75% (95% CI 77.52%-93.19%), specificity of 98.25% (95% CI 95.56-99.52%), a positive predictive value of 95.34% (95% CI 92.18%-97.26%) and a negative predictive value of 94.74% (95% CI 87.16%-97.95%). The overall predictive accuracy was 95.2% (95% CI 92.19%-97.28%).
Conclusion: The proposed bedside dengue severity scoring system was found to have good validity. Validating the score in different settings and patient populations is suggested.
التعليقات: Comment in: Indian Pediatr. 2023 May 15;60(5):341-342. (PMID: 37161953)
Comment in: Indian Pediatr. 2023 Jul 15;60(7):601. (PMID: 37424133)
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تواريخ الأحداث: Date Created: 20230209 Date Completed: 20230511 Latest Revision: 20230913
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10185942
PMID: 36757000
قاعدة البيانات: MEDLINE
الوصف
تدمد:0974-7559