دورية أكاديمية
أعرض في EDS

Anticoagulant Properties of Coated Fe-Pd Ferromagnetic Shape Memory Ribbons.

التفاصيل البيبلوغرافية
العنوان: Anticoagulant Properties of Coated Fe-Pd Ferromagnetic Shape Memory Ribbons.
المؤلفون: Bunge A; National Institute R&D for Isotopic and Molecular Technology, 67-103 Donat Street, 400293 Cluj-Napoca, Romania., Chiriac A; Department of Neurosurgery, 'Grigore T. Popa' University of Medicine and Pharmacy, Str. Universității nr. 16, 700115 Iasi, Romania., Sofronie M; National Institute of Materials Physics, Atomistilor Street 405A, 077125 Magurele, Romania., Crăciunescu I; National Institute R&D for Isotopic and Molecular Technology, 67-103 Donat Street, 400293 Cluj-Napoca, Romania., Porav AS; National Institute R&D for Isotopic and Molecular Technology, 67-103 Donat Street, 400293 Cluj-Napoca, Romania., Turcu R; National Institute R&D for Isotopic and Molecular Technology, 67-103 Donat Street, 400293 Cluj-Napoca, Romania.
المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 26; Vol. 24 (3). Date of Electronic Publication: 2023 Jan 26.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, [2000-
مواضيع طبية MeSH: Anticoagulants* , Shape Memory Alloys*, Palladium ; Surface Properties ; Alloys/chemistry ; Iron ; Coated Materials, Biocompatible/pharmacology ; Coated Materials, Biocompatible/chemistry
مستخلص: Shape memory alloys, especially ferromagnetic shape memory alloys, are interesting new materials for the manufacturing of stents. Iron-palladium alloys in particular can be used to manufacture self-expanding temporary stents due to their optimum rate of degradation, which is between that of magnesium and pure iron, two metals commonly used in temporary stent research. In order to avoid blood clotting upon the introduction of the stent, they are often coated with anticoagulants. In this study, sulfated pectin, a heparin mimetic, was synthesized in different ways and used as coating on multiple iron-palladium alloys. The static and dynamic prothrombin time (PT) and activated partial thromboplastin time (APTT) of the prepared materials were compared to samples uncoated or coated with polyethylene glycol. While no large differences were observed in the prothrombin time measurements, the activated partial thromboplastin time increased significantly with all alloys coated with sulfated pectin. Aside from that, sulfated pectin synthesized by different methods also caused slight changes in the activated partial thromboplastin time. These findings show that iron-palladium alloys can be coated with anticoagulants to improve their utility as material for temporary stents. Sulfated pectin was characterized by nuclear magnetic resonance (NMR) and Fourier-transform infrared (FTIR) spectroscopy, and the coated alloys by scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDX).
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معلومات مُعتمدة: PN-III-P1-1.2-PCCDI-2017-0062, contract no. 58 Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii; Research Center and Advanced Technologies for Alternative Energies - CETATEA - 623/11.03.2014 Ministerul Cercetării și Inovării
فهرسة مساهمة: Keywords: anticoagulant; ferromagnetic shape memory alloy; iron–palladium alloy; melt spinning; sulfated pectin
المشرفين على المادة: 0 (Anticoagulants)
0 (Shape Memory Alloys)
5TWQ1V240M (Palladium)
0 (Alloys)
E1UOL152H7 (Iron)
0 (Coated Materials, Biocompatible)
تواريخ الأحداث: Date Created: 20230211 Date Completed: 20230214 Latest Revision: 20230214
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9917221
DOI: 10.3390/ijms24032452
PMID: 36768774
قاعدة البيانات: MEDLINE
الوصف
تدمد:1422-0067
DOI:10.3390/ijms24032452