دورية أكاديمية
أعرض في EDS

Different gut microbiota in U.S. formula-fed infants consuming a meat vs. dairy-based complementary foods: A randomized controlled trial.

التفاصيل البيبلوغرافية
العنوان: Different gut microbiota in U.S. formula-fed infants consuming a meat vs. dairy-based complementary foods: A randomized controlled trial.
المؤلفون: Tang M; Section of Nutrition, Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States., Ma C; Department of Statistics, University of Michigan, Ann Arbor, MI, United States., Weinheimer-Haus EM; Division of Gastroenterology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, United States., Robertson CE; Division of Infectious Disease, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States., Kofonow JM; Division of Infectious Disease, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States., Berman LM; Section of Nutrition, Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States., Waljee A; Division of Gastroenterology, Department of Internal Medicine, Michigan Medicine, Ann Arbor, MI, United States.; Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, United States., Zhu J; Department of Statistics, University of Michigan, Ann Arbor, MI, United States., Frank DN; Division of Infectious Disease, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States., Krebs NF; Section of Nutrition, Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
المصدر: Frontiers in nutrition [Front Nutr] 2023 Jan 26; Vol. 9, pp. 1063518. Date of Electronic Publication: 2023 Jan 26 (Print Publication: 2022).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Frontiers Media S. A Country of Publication: Switzerland NLM ID: 101642264 Publication Model: eCollection Cited Medium: Print ISSN: 2296-861X (Print) Linking ISSN: 2296861X NLM ISO Abbreviation: Front Nutr Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Lausanne, Switzerland : Frontiers Media S. A., [2014]-
مستخلص: Objective: This project aimed to evaluate the impact of meat- vs. dairy-based complementary foods on gut microbiota and whether it relates to growth.
Design: Full-term, formula-fed infants were recruited from the metro Denver area (Colorado, US) and randomized to a meat- or dairy-based complementary diet from 5 to 12 months of age. Infant's length and weight were measured, and stool samples were collected at 5, 10, and 12 months for 16S rRNA gene sequencing and short-chain fatty acids (SCFAs) quantification.
Results: Sixty-four infants completed the dietary intervention ( n = 32/group). Weight-for-age Z (WAZ) scores increased in both groups and length-for-age Z scores (LAZ) increased in the meat group only, which led to a significant group-by-time interaction ( P = 0.02) of weight-for-length Z (WLZ) score. Microbiota composition (Beta-diversity) differed between groups at 12 months (weighted PERMANOVA P = 0.01) and had a group-by-time interaction of P = 0.09. Microbial community richness (Chao1) increased in the meat group only. Genus Akkermansia had a significant group-by-time interaction and increased in the dairy group and decreased in the meat group. A significant fold change of butyric acid from 5 to 12 months was found in the meat group (+1.75, P = 0.011) but not in the dairy group. Regression analysis showed that Chao1 had a negative association with WLZ and WAZ. Several genera also had significant associations with all growth Z scores.
Conclusion: Complementary feeding not only impacts infant growth but also affects gut microbiota maturation. Complementary food choices can affect both the gut microbiota diversity and structures and these changes in gut microbiota are associated with infant growth.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2023 Tang, Ma, Weinheimer-Haus, Robertson, Kofonow, Berman, Waljee, Zhu, Frank and Krebs.)
References: CMAJ. 2013 Mar 19;185(5):385-94. (PMID: 23401405)
BMC Pediatr. 2017 Feb 14;17(1):54. (PMID: 28196533)
Scand J Gastroenterol. 1988 Mar;23(2):178-82. (PMID: 3363290)
BMC Bioinformatics. 2009 Oct 29;10:362. (PMID: 19874596)
J Appl Bacteriol. 1991 Jun;70(6):443-59. (PMID: 1938669)
Genome Res. 1998 Mar;8(3):175-85. (PMID: 9521921)
Nature. 2006 Dec 21;444(7122):1027-31. (PMID: 17183312)
Microbiome. 2014 May 05;2:15. (PMID: 24910773)
Am J Clin Nutr. 2008 May;87(5):1576S-1581S. (PMID: 18469291)
Nat Rev Gastroenterol Hepatol. 2022 Oct;19(10):625-637. (PMID: 35641786)
Trends Microbiol. 2019 Feb;27(2):131-147. (PMID: 30529020)
Sci Rep. 2020 Sep 25;10(1):15792. (PMID: 32978424)
Science. 2016 Feb 19;351(6275):. (PMID: 26912898)
J Bacteriol. 1991 Jan;173(2):697-703. (PMID: 1987160)
Int J Obes (Lond). 2022 Jul;46(7):1351-1358. (PMID: 35428865)
Adv Exp Med Biol. 2005;569:69-79. (PMID: 16137110)
Sci Rep. 2019 Jun 3;9(1):8167. (PMID: 31160673)
Methods. 2018 Oct 1;149:59-68. (PMID: 29704665)
Microbiome. 2017 Jan 17;5(1):4. (PMID: 28095889)
Nutrients. 2021 Jan 27;13(2):. (PMID: 33513734)
Sci Rep. 2015 Oct 14;5:15220. (PMID: 26463271)
Bioinformatics. 2012 Jul 15;28(14):1823-9. (PMID: 22556368)
Appl Environ Microbiol. 2011 May;77(10):3219-26. (PMID: 21421784)
Ecol Lett. 2011 Jan;14(1):19-28. (PMID: 21070562)
J Pediatr. 2013 Aug;163(2):416-23. (PMID: 23452586)
Am J Clin Nutr. 2018 May 1;107(5):734-742. (PMID: 29722841)
Nucleic Acids Res. 2013 Jan;41(Database issue):D590-6. (PMID: 23193283)
Science. 2013 Mar 1;339(6123):1084-8. (PMID: 23328391)
Nature. 2009 Jan 22;457(7228):480-4. (PMID: 19043404)
Oncogene. 2022 Feb;41(9):1269-1280. (PMID: 35087236)
mSphere. 2016 Feb 10;1(1):. (PMID: 27303699)
Genome Res. 1998 Mar;8(3):186-94. (PMID: 9521922)
Sci Rep. 2019 Sep 9;9(1):12893. (PMID: 31501455)
Genome Biol. 2021 Jul 14;22(1):209. (PMID: 34261503)
J Immunol. 2012 Oct 15;189(8):3805-14. (PMID: 22988033)
Nat Methods. 2012 Mar 04;9(4):357-9. (PMID: 22388286)
JAMA Pediatr. 2018 Jul 2;172(7):e181161. (PMID: 29868719)
J Pediatr. 2019 Mar;206:78-82. (PMID: 30413312)
Genes (Basel). 2020 Oct 22;11(11):. (PMID: 33105702)
Proc Natl Acad Sci U S A. 1985 Oct;82(20):6955-9. (PMID: 2413450)
Front Endocrinol (Lausanne). 2017 Dec 13;8:349. (PMID: 29326657)
Clin Nutr. 2022 Aug;41(8):1680-1688. (PMID: 35777107)
Bioinformatics. 2013 Dec 1;29(23):3100-1. (PMID: 24021386)
PLoS One. 2013 Jul 02;8(7):e67019. (PMID: 23843979)
J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Feb 5;784(2):395-403. (PMID: 12505787)
Bioinformatics. 2011 Aug 15;27(16):2194-200. (PMID: 21700674)
معلومات مُعتمدة: K01 DK111665 United States DK NIDDK NIH HHS; P30 DK048520 United States DK NIDDK NIH HHS; UL1 TR001082 United States TR NCATS NIH HHS
فهرسة مساهمة: Keywords: RCT—randomized controlled trial; complementary feeding; growth; gut microbiota; infant
تواريخ الأحداث: Date Created: 20230213 Latest Revision: 20240421
رمز التحديث: 20240421
مُعرف محوري في PubMed: PMC9909089
DOI: 10.3389/fnut.2022.1063518
PMID: 36778973
قاعدة البيانات: MEDLINE
الوصف
تدمد:2296-861X
DOI:10.3389/fnut.2022.1063518