دورية أكاديمية

Congenital Fibrosis of Extraocular Muscles: A Systematic Review and Meta-Analysis.

التفاصيل البيبلوغرافية
العنوان: Congenital Fibrosis of Extraocular Muscles: A Systematic Review and Meta-Analysis.
المؤلفون: Van Swol JM; College of Medicine, Medical University of South Carolina, Charleston, South Carolina., Myers WK; College of Medicine, Medical University of South Carolina, Charleston, South Carolina., Nguyen SA; Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina., Wilson ME; Department of Ophthalmology-Pediatrics, Medical University of South Carolina, Charleston, South Carolina.
المصدر: Journal of binocular vision and ocular motility [J Binocul Vis Ocul Motil] 2023 Apr-Jun; Vol. 73 (2), pp. 43-52. Date of Electronic Publication: 2023 Feb 13.
نوع المنشور: Meta-Analysis; Systematic Review; Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Taylor & Francis Group Country of Publication: United States NLM ID: 101730067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2576-1218 (Electronic) Linking ISSN: 2576117X NLM ISO Abbreviation: J Binocul Vis Ocul Motil Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Philadelphia, PA] : Taylor & Francis Group, [2018]-
مواضيع طبية MeSH: Ophthalmoplegia*/surgery , Strabismus*/congenital, Humans ; Oculomotor Muscles/surgery ; Oculomotor Muscles/pathology ; Fibrosis
مستخلص: Purpose: To quantify typical disease characteristics for patients with congenital fibrosis of the extraocular muscles (CFEOM) including pre-and post-surgical ocular alignment and head positioning as well as average improvement with surgical intervention.
Patients and Methods: This investigation is a systematic review and meta-analysis. All studies detailing surgical intervention in cohorts of individuals with CFEOM were included. Ocular alignment and head positioning before and after surgery was recorded. Meta-analyses were performed to quantify these findings along with other patient characteristics across all included studies.
Results: The estimated average improvement in vertical alignment for patients with unilateral and bilateral CFEOM was 34.8 pd (prism diopters) and 21.27 pd, respectively. For horizontal alignment, patients with unilateral and bilateral CFEOM improved an average of 25.39 pd and 10.99 pd after surgery, respectively. There was no significant difference between the two most common surgeries used to address hypotropia and blepharoptosis in this patient population. The estimated proportion of patients with post-surgical head alignment within 5-9° was 60.64% and was 28.25% for patients with<5° of alignment.
Conclusion: This study was able to illuminate many characteristic features of patients with CFEOM. Surgical intervention for the ocular alignment and head positioning of these patients demonstrates promising utility.
فهرسة مساهمة: Keywords: CFEOM; Congenital; extraocular muscles; fibrosis; strabismus
تواريخ الأحداث: Date Created: 20230213 Date Completed: 20230428 Latest Revision: 20230428
رمز التحديث: 20231215
PMID: 36780505
قاعدة البيانات: MEDLINE