دورية أكاديمية
Renal oximetry for early acute kidney injury detection in neonates with hypoxic ischemic encephalopathy receiving therapeutic hypothermia.
| العنوان: | Renal oximetry for early acute kidney injury detection in neonates with hypoxic ischemic encephalopathy receiving therapeutic hypothermia. |
|---|---|
| المؤلفون: | Rumpel JA; Division of Neonatology, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Jarumpel@uams.edu.; Arkansas Children's Hospital, One Children's Way Slot 512-5, Little Rock, AR, 72205, USA. Jarumpel@uams.edu., Spray BJ; Arkansas Children's Research Institute, Little Rock, AR, USA., Frymoyer A; Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA., Rogers S; Division of Neonatology, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Cho SH; Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA., Ranabothu S; Division of Nephrology, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Blaszak R; Division of Nephrology, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Courtney SE; Division of Neonatology, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Chock VY; Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA, USA. |
| المصدر: | Pediatric nephrology (Berlin, Germany) [Pediatr Nephrol] 2023 Aug; Vol. 38 (8), pp. 2839-2849. Date of Electronic Publication: 2023 Feb 14. |
| نوع المنشور: | Observational Study; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer International Country of Publication: Germany NLM ID: 8708728 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-198X (Electronic) Linking ISSN: 0931041X NLM ISO Abbreviation: Pediatr Nephrol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Berlin : Springer International Original Publication: Berlin : Springer International, c1987- |
| مواضيع طبية MeSH: | Hypoxia-Ischemia, Brain*/complications , Hypoxia-Ischemia, Brain*/diagnosis , Hypoxia-Ischemia, Brain*/therapy , Acute Kidney Injury*/diagnosis , Acute Kidney Injury*/etiology , Acute Kidney Injury*/therapy , Hypothermia, Induced*/adverse effects , Hypothermia, Induced*/methods, Infant, Newborn ; Infant ; Female ; Pregnancy ; Humans ; Kidney ; Oximetry |
| مستخلص: | Background: Neonates with hypoxic ischemic encephalopathy (HIE) receiving therapeutic hypothermia are at high risk of acute kidney injury (AKI). Methods: We performed a two-site prospective observational study from 2018 to 2019 to evaluate the utility of renal near-infrared spectroscopy (NIRS) in detecting AKI in 38 neonates with HIE receiving therapeutic hypothermia. AKI was defined by a delayed rate of serum creatinine decline (< 33% on day 3 of life, < 40% on day 5, and < 46% on day 7). Renal saturation (R Results: AKI occurred in 20 of 38 neonates (53%). During the first 96 HOL, R Conclusions: Lower RFTOE on renal NIRS and pH on infant first blood gas may be early predictors for AKI in neonates with HIE receiving therapeutic hypothermia. A higher resolution version of the Graphical abstract is available as Supplementary information. (© 2023. The Author(s), under exclusive licence to International Pediatric Nephrology Association.) |
| References: | O’Dea M, Sweetman D, Bonifacio SL, El-Dib M, Austin T, Molloy EJ (2020) Management of multi organ dysfunction in neonatal encephalopathy. Front Pediatr 8:239. https://doi.org/10.3389/fped.2020.00239. (PMID: 10.3389/fped.2020.00239325000507243796) Sarafidis K, Tsepkentzi E, Agakidou E, Diamanti E, Taparkou A, Soubasi V, Papachristou F, Drossou V (2012) Serum and urine acute kidney injury biomarkers in asphyxiated neonates. Pediatr Nephrol 27:1575–1582. https://doi.org/10.1007/s00467-012-2162-4. (PMID: 10.1007/s00467-012-2162-422532328) Rumpel J, Spray BJ, Chock VY, Kirkley MJ, Slagle CL, Frymoyer A, Cho SH, Gist KM, Blaszak R, Poindexter B, Courtney SE (2022) Urine biomarkers for the assessment of acute kidney injury in neonates with hypoxic ischemic encephalopathy receiving therapeutic hypothermia. J Pediatr 241:133-140.e3. https://doi.org/10.1016/j.jpeds.2021.08.090. (PMID: 10.1016/j.jpeds.2021.08.09034547334) Selewski DT, Jordan BK, Askenazi DJ, Dechert RE, Sarkar S (2013) Acute kidney injury in asphyxiated newborns treated with therapeutic hypothermia. J Pediatr 162:725-729.e1. https://doi.org/10.1016/j.jpeds.2012.10.002. (PMID: 10.1016/j.jpeds.2012.10.00223149172) Alaro D, Bashir A, Musoke R, Wanaiana L (2014) Prevalence and outcomes of acute kidney injury in term neonates with perinatal asphyxia. Afr Health Sci 14:682–688. https://www.ajol.info/index.php/ahs/article/view/107254. Oncel MY, Canpolat FE, Arayici S, Alyamac Dizdar E, Uras N, Oguz SS (2016) Urinary markers of acute kidney injury in newborns with perinatal asphyxia. Ren Fail 38:882–888. https://doi.org/10.3109/0886022X.2016.1165070. (PMID: 10.3109/0886022X.2016.116507027055689) Sweetman DU, Onwuneme C, Watson WR, O’Neill A, Murphy JF, Molloy EJ (2016) Renal function and novel urinary biomarkers in infants with neonatal encephalopathy. Acta Paediatr 105:e513–e519. https://doi.org/10.1111/apa.13555. (PMID: 10.1111/apa.1355527551944) Essajee F, Were F, Admani B (2015) Urine neutrophil gelatinase-associated lipocalin in asphyxiated neonates: a prospective cohort study. Pediatr Nephrol 30:1189–1196. https://doi.org/10.1007/s00467-014-3035-9. (PMID: 10.1007/s00467-014-3035-925894565) Altit G, Bhombal S, Tacy TA, Chock VY (2018) End-organ saturation differences in early neonatal transition for left- versus right-sided congenital heart disease. Neonatology 114:53–61. https://doi.org/10.1159/000487472. (PMID: 10.1159/00048747229649824) Sood BG, McLaughlin K, Cortez J (2015) Near-infrared spectroscopy: applications in neonates. Semin Fetal Neonatal Med 20:164–172. https://doi.org/10.1016/j.siny.2015.03.008. (PMID: 10.1016/j.siny.2015.03.00825934116) Harer MW, Adegboro CO, Richard LJ, McAdams RM (2021) Non-invasive continuous renal tissue oxygenation monitoring to identify preterm neonates at risk for acute kidney injury. Pediatr Nephrol 36:1617–1625. https://doi.org/10.1007/s00467-020-04855-2. (PMID: 10.1007/s00467-020-04855-233389091) Bonsante F, Ramful D, Binquet C, Samperiz S, Daniel S, Gouyon JB, Iacobelli S (2019) Low renal oxygen saturation at near-infrared spectroscopy on the first day of life is associated with developing acute kidney injury in very preterm infants. Neonatology 115:198–204. https://doi.org/10.1159/000494462. (PMID: 10.1159/00049446230645992) Dorum BA, Ozkan H, Cetinkaya M, Koksal N (2021) Regional oxygen saturation and acute kidney injury in premature infants. Pediatr Int 63:290–294. https://doi.org/10.1111/ped.14377. (PMID: 10.1111/ped.1437732634851) Ruf B, Bonelli V, Balling G, Hörer J, Nagdyman N, Braun SL, Ewert P, Reiter K (2015) Intraoperative renal near-infrared spectroscopy indicates developing acute kidney injury in infants undergoing cardiac surgery with cardiopulmonary bypass: a case-control study. Crit Care 19:27. https://doi.org/10.1186/s13054-015-0760-9. (PMID: 10.1186/s13054-015-0760-9256313904336470) Zhang D, Ouyang C, Zhao X, Cui B, Dai F, Meng L, Ma J (2021) Renal tissue desaturation and acute kidney injury in infant cardiac surgery: a prospective propensity score-matched cohort study. Br J Anaesth 127:620–628. https://doi.org/10.1016/j.bja.2021.06.045. (PMID: 10.1016/j.bja.2021.06.04534446224) Chock VY, Frymoyer A, Yeh CG, Van Meurs KP (2018) Renal saturation and acute kidney injury in neonates with hypoxic ischemic encephalopathy undergoing therapeutic hypothermia. J Pediatr 200:232-239.e1. https://doi.org/10.1016/j.jpeds.2018.04.076. (PMID: 10.1016/j.jpeds.2018.04.07629866591) Sarnat HB, Sarnat MS (1976) Neonatal encephalopathy following fetal distress. A clinical and electroencephalographic study. Arch Neurol 33:696–705. https://doi.org/10.1001/archneur.1976.00500100030012. (PMID: 10.1001/archneur.1976.00500100030012987769) Shankaran S, Laptook AR, Ehrenkranz RA, Tyson JE, McDonald SA, Donovan EF, Fanaroff AA, Poole WK, Wright LL, Higgins RD, Finer NN, Carlo WA, Duara S, Oh W, Cotten CM, Stevenson DK, Stoll BJ, Lemons JA, Guillet R, Jobe AH; National Institute of Child Health and Human Development Neonatal Research Network (2005) Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med 353:1574–1584. https://doi.org/10.1056/NEJMcps050929. Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG (2009) Research electronic data capture (REDCap)–a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform 42:377–381. https://doi.org/10.1016/j.jbi.2008.08.010. (PMID: 10.1016/j.jbi.2008.08.01018929686) Gupta C, Massaro AN, Ray PE (2016) A new approach to define acute kidney injury in term newborns with hypoxic ischemic encephalopathy. Pediatr Nephrol 31:1167–1178. https://doi.org/10.1007/s00467-016-3317-5. (PMID: 10.1007/s00467-016-3317-5268577104882244) Jetton JG, Boohaker LJ, Sethi SK, Wazir S, Rohatgi S, Soranno DE, Chishti AS, Woroniecki R, Mammen C, Swanson JR, Sridhar S, Wong CS, Kupferman JC, Griffin RL, Askenazi DJ; Neonatal Kidney Collaborative (NKC) (2017) Incidence and outcomes of neonatal acute kidney injury (AWAKEN): a multicentre, multinational, observational cohort study. Lancet Child Adolesc Health 1:184–194. https://doi.org/10.1016/S2352-4642(17)30069-X. Zappitelli M, Ambalavanan N, Askenazi DJ, Moxey-Mims MM, Kimmel PL, Star RA, Abitbol CL, Brophy PD, Hidalgo G, Hanna M, Morgan CM, Raju TNK, Ray P, Reyes-Bou Z, Roushdi A, Goldstein SL (2017) Developing a neonatal acute kidney injury research definition: a report from the NIDDK neonatal AKI workshop. Pediatr Res 82:569–573. https://doi.org/10.1038/pr.2017.136. (PMID: 10.1038/pr.2017.136286047609673450) Gist KM, Goldstein SL, Wrona J, Alten JA, Basu RK, Cooper DS, Soranno DE, Duplantis J, Altmann C, Gao Z, Faubel S (2017) Kinetics of the cell cycle arrest biomarkers (TIMP-2*IGFBP-7) for prediction of acute kidney injury in infants after cardiac surgery. Pediatr Nephrol 32:1611–1619. https://doi.org/10.1007/s00467-017-3655-y. (PMID: 10.1007/s00467-017-3655-y28382566) Al-Wassia H, Alshaikh B, Sauve R (2013) Prophylactic theophylline for the prevention of severe renal dysfunction in term and post-term neonates with perinatal asphyxia: a systematic review and meta-analysis of randomized controlled trials. J Perinatol 33:271–277. https://doi.org/10.1038/jp.2012.97. (PMID: 10.1038/jp.2012.9722836872) Bakr AF (2005) Prophylactic theophylline to prevent renal dysfunction in newborns exposed to perinatal asphyxia–a study in a developing country. Pediatr Nephrol 20:1249–1252. https://doi.org/10.1007/s00467-005-1980-z. (PMID: 10.1007/s00467-005-1980-z15947981) Bhatt GC, Gogia P, Bitzan M, Das RR (2019) Theophylline and aminophylline for prevention of acute kidney injury in neonates and children: a systematic review. Arch Dis Child 104:670–679. https://doi.org/10.1136/archdischild-2018-315805. (PMID: 10.1136/archdischild-2018-31580530798259) Bhat MA, Shah ZA, Makhdoomi MS, Mufti MH (2006) Theophylline for renal function in term neonates with perinatal asphyxia: a randomized, placebo-controlled trial. J Pediatr 149:180–184. https://doi.org/10.1016/j.jpeds.2006.03.053. (PMID: 10.1016/j.jpeds.2006.03.05316887430) Jenik AG, Ceriani Cernadas JM, Gorenstein A, Ramirez JA, Vain N, Armadans M, Ferraris JR (2000) A randomized, double-blind, placebo-controlled trial of the effects of prophylactic theophylline on renal function in term neonates with perinatal asphyxia. Pediatrics 105:E45. https://doi.org/10.1542/peds.105.4.e45. (PMID: 10.1542/peds.105.4.e4510742366) Chock VY, Cho SH, Frymoyer A (2021) Aminophylline for renal protection in neonatal hypoxic-ischemic encephalopathy in the era of therapeutic hypothermia. Pediatr Res 89:974–980. https://doi.org/10.1038/s41390-020-0999-y. (PMID: 10.1038/s41390-020-0999-y32503030) Emma F, Montini G, Parikh SM, Salviati L (2016) Mitochondrial dysfunction in inherited renal disease and acute kidney injury. Nat Rev Nephrol 12:267–280. https://doi.org/10.1038/nrneph.2015.214. (PMID: 10.1038/nrneph.2015.214268040195469549) Massaro AN, Bouyssi-Kobar M, Chang T, Vezina LG, du Plessis AJ, Limperopoulos C (2013) Brain perfusion in encephalopathic newborns after therapeutic hypothermia. AJNR Am J Neuroradiol 34:1649–1655. https://doi.org/10.3174/ajnr.A3422. (PMID: 10.3174/ajnr.A3422234938984376377) Perazzo S, Revenis M, Massaro A, Short BL, Ray PE (2020) A new approach to recognize neonatal impaired kidney function. Kidney Int Rep 5:2301–2312. https://doi.org/10.1016/j.ekir.2020.09.043. (PMID: 10.1016/j.ekir.2020.09.043333051247710891) Cavallin F, Rubin G, Vidal E, Cainelli E, Bonadies L, Suppiej A, Trevisanuto D (2020) Prognostic role of acute kidney injury on long-term outcome in infants with hypoxic-ischemic encephalopathy. Pediatr Nephrol 35:477–483. https://doi.org/10.1007/s00467-019-04406-4. (PMID: 10.1007/s00467-019-04406-431828471) Sarkar S, Askenazi DJ, Jordan BK, Bhagat I, Bapuraj JR, Dechert RE, Selewski DT (2014) Relationship between acute kidney injury and brain MRI findings in asphyxiated newborns after therapeutic hypothermia. Pediatr Res 75:431–435. https://doi.org/10.1038/pr.2013.230. (PMID: 10.1038/pr.2013.23024296799) Yan ES, Chock VY, Bonifacio SL, Dahlen A, Guimaraes CV, Altit G, Bhombal S, Van Meurs K (2022) Association between multi-organ dysfunction and adverse outcome in infants with hypoxic ischemic encephalopathy. J Perinatol 42:907–913. https://doi.org/10.1038/s41372-022-01413-6. (PMID: 10.1038/s41372-022-01413-635578019) Kirkley MJ, Boohaker L, Griffin R, Soranno DE, Gien J, Askenazi D, Gist KM; Neonatal Kidney Collaborative (NKC) (2019) Acute kidney injury in neonatal encephalopathy: an evaluation of the AWAKEN database. Pediatr Nephrol 34:169–176. https://doi.org/10.1007/s00467-018-4068-2. Ustun N, Ovali F (2021) Risk factors and outcomes of acute kidney injury in neonates with persistent pulmonary hypertension of the newborn. Medeni Med J 36:193–200. https://doi.org/10.5222/MMJ.2021.22687. (PMID: 10.5222/MMJ.2021.22687349156768565581) Yum SK, Seo YM, Youn YA, Sung IK (2019) Preoperative metabolic acidosis and acute kidney injury after open laparotomy in the neonatal intensive care unit. Pediatr Int 61:994–1000. https://doi.org/10.1111/ped.13929. (PMID: 10.1111/ped.1392931267596) Charlton JR, Boohaker L, Askenazi D, Brophy PD, D’Angio C, Fuloria M, Gien J, Griffin R, Hingorani S, Ingraham S, Mian A, Ohls RK, Rastogi S, Rhee CJ, Revenis M, Sarkar S, Smith A, Starr M, Kent AL; Neonatal Kidney Collaborative (2019) Incidence and risk factors of early onset neonatal AKI. Clin J Am Soc Nephrol 14:184–195. https://doi.org/10.2215/CJN.03670318. Robertsson Grossmann K, Bárány P, Blennow M, Chromek M (2022) Acute kidney injury in infants with hypothermia-treated hypoxic-ischaemic encephalopathy: an observational population-based study. Acta Paediatr 111:86–92. https://doi.org/10.1111/apa.16078. (PMID: 10.1111/apa.1607834431538) Meersch M, Schmidt C, Hoffmeier A, Van Aken H, Wempe C, Gerss J, Zarbock A (2017) Prevention of cardiac surgery-associated AKI by implementing the KDIGO guidelines in high risk patients identified by biomarkers: the PrevAKI randomized controlled trial. Intensive Care Med 43:1551–1561. https://doi.org/10.1007/s00134-016-4670-3. Mintzer JP, Parvez B, Chelala M, Alpan G, LaGamma EF (2014) Quiescent variability of cerebral, renal, and splanchnic regional tissue oxygenation in very low birth weight neonates. J Neonatal Perinatal Med 7:199–206. https://doi.org/10.3233/NPM-14814035. (PMID: 10.3233/NPM-1481403525322996) |
| فهرسة مساهمة: | Keywords: Acute kidney injury; Hypoxic ischemic encephalopathy; Near-infrared spectroscopy; Neonates; Renal fractional tissue oxygen extraction; Therapeutic hypothermia |
| تواريخ الأحداث: | Date Created: 20230214 Date Completed: 20231023 Latest Revision: 20231026 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1007/s00467-023-05892-3 |
| PMID: | 36786860 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1432-198X |
|---|---|
| DOI: | 10.1007/s00467-023-05892-3 |