دورية أكاديمية
LncRNA-mediated Modulation of Endothelial Cells: Novel Progress in the Pathogenesis of Coronary Atherosclerotic Disease.
| العنوان: | LncRNA-mediated Modulation of Endothelial Cells: Novel Progress in the Pathogenesis of Coronary Atherosclerotic Disease. |
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| المؤلفون: | Ouyang S; Key Lab for Arteriosclerology of Hunan Province, International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province, Institute of Cardiovascular Disease, University of South China, Hengyang 421001, China.; Key Laboratory of Heart Failure Prevention & Treatment of Hengyang, Department of Cardiovascular Medicine, Hengyang Medical School, The Second Affiliated Hospital, Clinical Medicine Research Center of Arteriosclerotic Disease of Hunan Province, University of South China, Hunan 421001, China., Zhou ZX; Key Lab for Arteriosclerology of Hunan Province, International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province, Institute of Cardiovascular Disease, University of South China, Hengyang 421001, China., Liu HT; Key Lab for Arteriosclerology of Hunan Province, International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province, Institute of Cardiovascular Disease, University of South China, Hengyang 421001, China., Ren Z; Key Lab for Arteriosclerology of Hunan Province, International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province, Institute of Cardiovascular Disease, University of South China, Hengyang 421001, China., Liu H; Key Lab for Arteriosclerology of Hunan Province, International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province, Institute of Cardiovascular Disease, University of South China, Hengyang 421001, China., Deng NH; Key Lab for Arteriosclerology of Hunan Province, International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province, Institute of Cardiovascular Disease, University of South China, Hengyang 421001, China., Tian KJ; Key Lab for Arteriosclerology of Hunan Province, International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province, Institute of Cardiovascular Disease, University of South China, Hengyang 421001, China., Zhou K; Key Lab for Arteriosclerology of Hunan Province, International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province, Institute of Cardiovascular Disease, University of South China, Hengyang 421001, China., Xie HL; Key Lab for Arteriosclerology of Hunan Province, International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province, Institute of Cardiovascular Disease, University of South China, Hengyang 421001, China., Jiang ZS; Key Lab for Arteriosclerology of Hunan Province, International Joint Laboratory for Arteriosclerotic Disease Research of Hunan Province, Institute of Cardiovascular Disease, University of South China, Hengyang 421001, China. |
| المصدر: | Current medicinal chemistry [Curr Med Chem] 2024; Vol. 31 (10), pp. 1251-1264. |
| نوع المنشور: | Review; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 9440157 Publication Model: Print Cited Medium: Internet ISSN: 1875-533X (Electronic) Linking ISSN: 09298673 NLM ISO Abbreviation: Curr Med Chem Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Saif Zone, Sharjah, U.A.E. : Bentham Science Publishers Original Publication: Schiphol, The Netherlands : Bentham Science Publishers, |
| مواضيع طبية MeSH: | RNA, Long Noncoding*/genetics , RNA, Long Noncoding*/metabolism , Coronary Artery Disease*/genetics , Coronary Artery Disease*/pathology , Atherosclerosis*/metabolism , Cardiovascular Diseases*/metabolism, Humans ; Endothelial Cells/metabolism |
| مستخلص: | Coronary atherosclerotic disease (CAD) is a common cardiovascular disease and an important cause of death. Moreover, endothelial cells (ECs) injury is an early pathophysiological feature of CAD, and long noncoding RNAs (lncRNAs) can modulate gene expression. Recent studies have shown that lncRNAs are involved in the pathogenesis of CAD, especially by regulating ECs. In this review, we summarize the novel progress of lncRNA-modulated ECs in the pathogenesis of CAD, including ECs proliferation, migration, adhesion, angiogenesis, inflammation, apoptosis, autophagy, and pyroptosis. Thus, as lncRNAs regulate ECs in CAD, lncRNAs will provide ideal and novel targets for the diagnosis and drug therapy of CAD. (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.) |
| معلومات مُعتمدة: | 2020SK2105 Special Funding for Construction of Innovative Provinces in Hunan Province; 2019YFA0801601 National Key Research and Development Program of China; 2021SK51712 Clinical Medical Technology Innovation Guide Project of Hunan Province; 2020SK4010 Special Funds for the Innovative Construction of Hunan Province; 2019jh426001 Special Funds for Science and Technology Plan Project of Hengyang; nk2020106 Research Project of the University of South China |
| فهرسة مساهمة: | Keywords: Long noncoding RNAs; coronary atherosclerotic heart disease; diagnosis; drug therapy; endothelial cells; smooth muscle cell. |
| المشرفين على المادة: | 0 (RNA, Long Noncoding) |
| تواريخ الأحداث: | Date Created: 20230215 Date Completed: 20240112 Latest Revision: 20240112 |
| رمز التحديث: | 20240112 |
| DOI: | 10.2174/0929867330666230213100732 |
| PMID: | 36788688 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1875-533X |
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| DOI: | 10.2174/0929867330666230213100732 |