دورية أكاديمية
أعرض في EDS

Cortical mechanisms of sensory trick in cervical dystonia.

التفاصيل البيبلوغرافية
العنوان: Cortical mechanisms of sensory trick in cervical dystonia.
المؤلفون: Manzo N; Department of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, Rome 00185, Italy; IRCCS San Camillo Hospital, Via Alberoni 70, Venice 30126, Italy., Leodori G; Department of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, Rome 00185, Italy; IRCCS Neuromed, Via Atinense 18, Pozzilli, IS 86077, Italy., Ruocco G; Department of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, Rome 00185, Italy., Belvisi D; Department of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, Rome 00185, Italy; IRCCS Neuromed, Via Atinense 18, Pozzilli, IS 86077, Italy., Merchant SHI; Beth Israel Deaconess Medical Center/ Harvard Medical School, Boston, USA., Fabbrini G; Department of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, Rome 00185, Italy; IRCCS Neuromed, Via Atinense 18, Pozzilli, IS 86077, Italy., Berardelli A; Department of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, Rome 00185, Italy; IRCCS Neuromed, Via Atinense 18, Pozzilli, IS 86077, Italy. Electronic address: alfredo.berardelli@uniroma1.it., Conte A; Department of Human Neurosciences, Sapienza University of Rome, Viale dell'Università 30, Rome 00185, Italy; IRCCS Neuromed, Via Atinense 18, Pozzilli, IS 86077, Italy.
المصدر: NeuroImage. Clinical [Neuroimage Clin] 2023; Vol. 37, pp. 103348. Date of Electronic Publication: 2023 Feb 11.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101597070 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-1582 (Electronic) Linking ISSN: 22131582 NLM ISO Abbreviation: Neuroimage Clin Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [Amsterdam] : Elsevier
مواضيع طبية MeSH: Torticollis* , Sensorimotor Cortex* , Movement Disorders*, Humans ; Movement/physiology ; Parietal Lobe ; Electroencephalography/methods ; Electromyography
مستخلص: Patients with cervical dystonia (CD) often show an improvement in dystonic posture after sensory trick (ST), though the mechanisms underlying ST remain unclear. In this study, we aimed to investigate the effects of ST on cortical activity in patients with CD and to explore the contribution of motor and sensory components to ST mechanisms. To this purpose, we studied 15 CD patients with clinically effective ST, 17 without ST, and 14 healthy controls (HCs) who mimicked the ST. We used electroencephalographic (EEG) recordings and electromyography (EMG) data from bilateral sternocleidomastoid (SCM) muscles. We compared ST-related EEG spectral changes from sensorimotor and posterior parietal areas and EMG power changes between groups. To better understand the contribution of motor and sensory components to ST, we tested EEG and EMG correlates of three different conditions mimicking ST, the first without skin touch ("no touch" condition), the second without voluntary movements ("passive" condition), and finally without arm movements ("examiner touch" condition). Results showed ST-related alpha desynchronization in the sensorimotor cortex and theta desynchronization in the sensorimotor and posterior parietal cortex. Both spectral changes were more significant during maneuver execution in CD patients with ST than in CD patients without ST and HCs who mimicked the ST. Differently, the "no touch", "passive", or "examiner touch" conditions did not show significant differences in EEG or EMG changes determined by ST execution/mimicking between CD patients with or without ST. A higher desynchronization within alpha and theta bands in the sensorimotor and posterior parietal areas correlated with a more significant activity decrease in the contralateral SCM muscle, Findings from this study suggest that ST-related changes in the activity of sensorimotor and posterior parietal areas may restore dystonic posture and that both motor and sensory components contribute to the ST effect.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Dystonia; Event-related desynchronization; Posterior parietal cortex; Sensorimotor cortex; Sensory trick
تواريخ الأحداث: Date Created: 20230215 Date Completed: 20230321 Latest Revision: 20230413
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9950946
DOI: 10.1016/j.nicl.2023.103348
PMID: 36791488
قاعدة البيانات: MEDLINE
الوصف
تدمد:2213-1582
DOI:10.1016/j.nicl.2023.103348