دورية أكاديمية
أعرض في EDS

HIV-PASS (Pain and Sadness Support): Randomized Controlled Trial of a Behavioral Health Intervention for Interference Due to Pain in People Living With HIV, Chronic Pain, and Depression.

التفاصيل البيبلوغرافية
العنوان: HIV-PASS (Pain and Sadness Support): Randomized Controlled Trial of a Behavioral Health Intervention for Interference Due to Pain in People Living With HIV, Chronic Pain, and Depression.
المؤلفون: Uebelacker LA; From the Departments of Psychiatry and Human Behavior (Uebelacker, Pinkston, Caviness, Herman, Abrantes) and Family Medicine (Uebelacker, Weisberg), Alpert Medical School of Brown University; Behavioral Medicine and Addictions Research (Uebelacker, Anderson, Caviness, Herman, Abrantes, Stein), Butler Hospital; Department of Medicine (Pinkston), Alpert Medical School of Brown University; Lifespan Physicians Group (Pinkston), The Miriam Hospital, Providence, Rhode Island; Department of Medicine (Busch, Baker), Hennepin Healthcare; Department of Medicine (Busch, Baker), University of Minnesota, Minneapolis, Minnesota; VA Boston Healthcare System (Weisberg); Department of Psychiatry (Weisberg), Boston University School of Medicine; and Department of Health Law, Policy and Management(Stein), Boston University School of Public Health, Boston, Massachusetts., Pinkston MM, Busch AM, Baker JV, Anderson B, Caviness CM, Herman DS, Weisberg RB, Abrantes AM, Stein MD
المصدر: Psychosomatic medicine [Psychosom Med] 2023 Apr 01; Vol. 85 (3), pp. 250-259. Date of Electronic Publication: 2023 Feb 03.
نوع المنشور: Randomized Controlled Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0376505 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1534-7796 (Electronic) Linking ISSN: 00333174 NLM ISO Abbreviation: Psychosom Med Subsets: MEDLINE
أسماء مطبوعة: Publication: Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: Baltimore [etc.]
مواضيع طبية MeSH: Chronic Pain*/therapy , HIV Infections*/complications , HIV Infections*/therapy, Humans ; Depression/therapy ; HIV ; Sadness
مستخلص: Objective: This study aimed to determine whether HIV-Pain and Sadness Support (HIV-PASS), a collaborative behavioral health intervention based on behavioral activation, is associated with decreased pain-related interference with daily activities, depression, and other outcomes in people living with HIV.
Methods: We conducted a three-site clinical trial ( n = 187) in which we randomly assigned participants to receive either HIV-PASS or health education control condition. In both conditions, participants received seven intervention sessions, comprising an initial in-person joint meeting with the participant, their HIV primary care provider and a behavioral health specialist, and six, primarily telephone-based, meetings with the behavioral health specialist and participant. The intervention period lasted 3 months, and follow-up assessments were conducted for an additional 9 months.
Results: Compared with health education, HIV-PASS was associated with significantly lower pain-related interference with daily activities at the end of month 3 (our primary outcome; b = -1.31, 95% confidence interval = -2.28 to -0.34). We did not observe other differences between groups at 3 months in secondary outcomes that included worst or average pain in the past week, depression symptoms, anxiety, and perceived overall mental and physical health. There were no differences between groups on any outcomes at 12 months after enrollment.
Conclusions: A targeted intervention can have positive effects on pain interference. At the end of intervention, effects we found were in a clinically significant range. However, effects diminished once the intervention period ended.
Trial Registration: ClinicalTrials.gov NCT02766751.
(Copyright © 2023 by the American Psychosomatic Society.)
References: Slawek DE. People living with HIV and the emerging field of chronic pain—what is known about epidemiology, etiology, and management. Curr HIV/AIDS Rep 2021;18:436–42.
Madden VJ, Parker R, Goodin BR. Chronic pain in people with HIV: a common comorbidity and threat to quality of life. Pain Manag 2020;10:253–60.
Scott W, Arkuter C, Kioskli K, Kemp H, McCracken LM, Rice ASC, et al. Psychosocial factors associated with persistent pain in people with HIV: a systematic review with meta-analysis. Pain 2018;159:2461–76.
Uebelacker LA, Weisberg RB, Herman DS, Bailey GL, Pinkston-Camp MM, Stein MD. Chronic pain in HIV-infected patients: relationship to depression, substance use, and mental health and pain treatment. Pain Med 2015;16:1870–81.
Serota DP, Capozzi C, Lodi S, Colasanti JA, Forman LS, Tsui JI, et al. Predictors of pain-related functional impairment among people living with HIV on long-term opioid therapy. AIDS Care 2021;33:507–15.
Currie SR, Wang J. Chronic back pain and major depression in the general Canadian population. Pain 2004;107:54–60.
Mwesiga EK, Mugenyi L, Nakasujja N, Moore S, Kaddumukasa M, Sajatovic M. Depression with pain co morbidity effect on quality of life among HIV positive patients in Uganda: a cross sectional study. Health Qual Life Outcomes 2015;13:206.
Uebelacker LA, Cherenack EM, Busch A, Baker JV, Pinkston M, Gleason N, et al. Pharmacologic and non-pharmacologic treatments for chronic pain used by patients with pain, HIV, and depression. AIDS Behav 2022;26:864–73.
Koeppe J, Armon C, Lyda K, Nielsen C, Johnson S. Ongoing pain despite aggressive opioid pain management among persons with HIV. Clin J Pain 2010;26:190–8.
Merlin JS, Bulls HW, Vucovich LA, Edelman EJ, Starrels JL. Pharmacologic and non-pharmacologic treatments for chronic pain in individuals with HIV: a systematic review. AIDS Care 2016;28:1506–15.
Amaniti A, Sardeli C, Fyntanidou V, Papakonstantinou P, Dalakakis I, Mylonas A, et al. Pharmacologic and non-pharmacologic interventions for HIV-neuropathy pain. A systematic review and a meta-analysis. Medicina (Kaunas) 2019;55:762.
Bruce RD, Merlin J, Lum PJ, Ahmed E, Alexander C, Corbett AH, et al. 2017 HIV Medicine Association of Infectious Diseases Society of America clinical practice guideline for the management of chronic pain in patients living with human immunodeficiency virus. Clin Infect Dis 2017;65:1601–6.
Williams ACC, Fisher E, Hearn L, Eccleston C. Psychological therapies for the management of chronic pain (excluding headache) in adults. Cochrane Database Syst Rev 2020;8:CD007407.
Dimidjian S, Hollon SD, Dobson KS, Schmaling KB, Kohlenberg RJ, Addis ME, et al. Randomized trial of behavioral activation, cognitive therapy, and antidepressant medication in the acute treatment of adults with major depression. J Consult Clin Psychol 2006;74:658–70.
Vlaeyen JWS, Linton SJ. Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art. Pain 2000;85:317–32.
Turk DC, Robinson JP, Burwinkle T. Prevalence of fear of pain and activity in patients with fibromyalgia syndrome. J Pain 2004;5:483–90.
Trafton JA, Sorrell JT, Holodniy M, Pierson H, Link P, Combs A, et al. Outcomes associated with a cognitive-behavioral chronic pain management program implemented in three public HIV primary care clinics. J Behav Health Serv Res 2012;39:158–73.
Evans S, Fishman B, Spielman L, Haley A. Randomized trial of cognitive behavior therapy versus supportive psychotherapy for HIV-related peripheral neuropathic pain. Psychosomatics 2003;44:44–50.
Merlin JS, Westfall AO, Long D, Davies S, Saag M, Demonte W, et al. A randomized pilot trial of a novel behavioral intervention for chronic pain tailored to individuals with HIV. AIDS Behav 2018;22:2733–42.
Uebelacker LA, Weisberg RB, Herman DS, Bailey GL, Pinkston-Camp MM, Garnaat SL, et al. Pilot randomized trial of collaborative behavioral treatment for chronic pain and depression in persons living with HIV/AIDS. AIDS Behav 2016;20:1675–81.
Moitra E, Tarantino N, Garnaat SL, Pinkston MM, Busch AM, Weisberg RB, et al. Using behavioral psychotherapy techniques to address HIV patients’ pain, depression, and well-being. Psychotherapy (Chic) 2020;57:83–9.
Dobscha SK, Corson K, Perrin NA, Hanson GC, Leibowitz RQ, Doak MN, et al. Collaborative care for chronic pain in primary care: a cluster randomized trial. JAMA 2009;301:1242–52.
Pinkston MM, Busch AM, Stein M, Baker J, Caviness C, Herman D, et al. Improving functioning in HIV+ patients with chronic pain and comorbid depression: protocol for a randomized clinical trial testing a collaborative behavioral health intervention based on behavioral activation. Contemp Clin Trials 2022;119:106842.
Cleeland CS, Ryan KM. Pain assessment: global use of the Brief Pain Inventory. Ann Acad Med Singapore 1994;23:129–38.
Rush AJ, Trivedi MH, Ibrahim HM, Carmody TJ, Arnow B, Klein DN, et al. The 16-item Quick Inventory of Depressive Symptomatology (QIDS), Clinician Rating (QIDS-C), and Self-Report (QIDS-SR): a psychometric evaluation in patients with chronic major depression. Biol Psychiatry 2003;54:573–83.
First MB, Williams JBW, Karg RS, Spitzer RS. Structured Clinical Interview for DSM-5—Research Version (SCID-5 for DSM-5, Research Version; SCID-5-RV). Arlington, VA: American Psychiatric Association; 2015.
Schalet BD, Pilkonis PA, Yu L, Dodds N, Johnston KL, Yount S, et al. Clinical validity of PROMIS Depression, Anxiety, and Anger across diverse clinical samples. J Clin Epidemiol 2016;73:119–27.
Simoni JM, Kurth AE, Pearson CR, Pantalone DW, Merrill JO, Frick PA. Self-report measures of antiretroviral therapy adherence: a review with recommendations for HIV research and clinical management. AIDS Behav 2006;10:227–45.
Nieuwkerk PT, Oort FJ. Self-reported adherence to antiretroviral therapy for HIV-1 infection and virologic treatment response: a meta-analysis. J Acquir Immune Defic Syndr 2005;38:445–8.
Ware J, Kosinski MA, Dewey D. How to Score Version 2 of the SF-36 Health Survey. Lincoln, RI: QualityMetric Incorporated; 2000.
Guy W. ECDEU Assessment Manual for Psychopharmacology (DHEW Publication No. ADM 76-338). Washington, DC: US Government Printing Office; 1976.
National Institute for Health and Clinical Excellence. Clinical Guideline 23 (Amended): Depression: Management of Depression in Primary and Secondary Care. London, United Kingdom: National Institute for Health and Clinical Excellence; 2007.
Dworkin RH, Turk DC, Wyrwich KW, Beaton D, Cleeland CS, Farrar JT, et al. Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations. J Pain 2008;9:105–21.
Hegerl U, Mergl R. The clinical significance of antidepressant treatment effects cannot be derived from placebo-verum response differences. J Psychopharmacol 2010;24:445–8.
Azur MJ, Stuart EA, Frangakis C, Leaf PJ. Multiple imputation by chained equations: what is it and how does it work? Int J Methods Psychiatr Res 2011;20:40–9.
de Boer MR, Waterlander WE, Kuijper LD, Steenhuis IH, Twisk JW. Testing for baseline differences in randomized controlled trials: an unhealthy research behavior that is hard to eradicate. Int J Behav Nutr Phys Act 2015;12:4.
Qaseem A, Wilt TJ, McLean RM, Forciea MA, Denberg TD, et al; Clinical Guidelines Committee of the American College of Physicians. Noninvasive treatments for acute, subacute, and chronic low back pain: a clinical practice guideline from the American College of Physicians. Ann Intern Med 2017;166:514–30.
Cucciare MA, Sorrell JT, Trafton JA. Predicting response to cognitive-behavioral therapy in a sample of HIV-positive patients with chronic pain. J Behav Med 2009;32:340–8.
McLellan AT, Lewis DC, O’Brien CP, Kleber HD. Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluation. JAMA 2000;284:1689–95.
Wright MA, Adelani M, Dy C, O’Keefe R, Calfee RP. What is the impact of social deprivation on physical and mental health in orthopaedic patients? Clin Orthop Relat Res 2019;477:1825–35.
Ciharova M, Furukawa TA, Efthimiou O, Karyotaki E, Miguel C, Noma H, et al. Cognitive restructuring, behavioral activation and cognitive-behavioral therapy in the treatment of adult depression: a network meta-analysis. J Consult Clin Psychol 2021;89:563–74.
Busch AM, Uebelacker LA, Kalibatseva Z, Miller IW. Measuring homework completion in behavioral activation. Behav Modif 2010;34:310–29.
معلومات مُعتمدة: R01 NR015977 United States NR NINR NIH HHS
سلسلة جزيئية: ClinicalTrials.gov NCT02766751
تواريخ الأحداث: Date Created: 20230217 Date Completed: 20230405 Latest Revision: 20240402
رمز التحديث: 20240402
مُعرف محوري في PubMed: PMC10073275
DOI: 10.1097/PSY.0000000000001172
PMID: 36799731
قاعدة البيانات: MEDLINE
الوصف
تدمد:1534-7796
DOI:10.1097/PSY.0000000000001172