دورية أكاديمية

Shedding a light on the importance of photopatch testing: A 12-year experience in a dermatology unit.

التفاصيل البيبلوغرافية
العنوان: Shedding a light on the importance of photopatch testing: A 12-year experience in a dermatology unit.
المؤلفون: Codeço C; Occupational Medicine, Instituto Português de Oncologia, Coimbra, Portugal., Alves PB; Allergy and Clinical Immunology Unit, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal., Figueiredo AC; Dermatology Unit, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal., Flor D; Dermatology Unit, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal., Gonçalo M; Dermatology Unit, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.; Dermatology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
المصدر: Contact dermatitis [Contact Dermatitis] 2023 Jun; Vol. 88 (6), pp. 438-445. Date of Electronic Publication: 2023 Mar 01.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 7604950 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0536 (Electronic) Linking ISSN: 01051873 NLM ISO Abbreviation: Contact Dermatitis Subsets: MEDLINE
أسماء مطبوعة: Publication: <2005-> : Oxford : Wiley
Original Publication: Copenhagen, Munksgaard.
مواضيع طبية MeSH: Dermatology* , Dermatitis, Allergic Contact*/complications , Dermatitis, Photoallergic*/diagnosis , Dermatitis, Photoallergic*/etiology, Humans ; Retrospective Studies ; Allergens/adverse effects ; Sunscreening Agents/adverse effects ; Patch Tests/methods
مستخلص: Background: Photopatch testing has been standardized for diagnosing photoallergic contact dermatitis but is still infrequently used.
Objectives: To characterize photopatch test (PPT) results and their clinical relevance.
Methods: We collected retrospective data from patients photopatch tested in our Dermatology Unit (2010-2021), using the European PPT 'baseline' series, other allergens, and patient's own products, when appropriate.
Results: Out of 223 patients, 75 patients (33.6%) were reactive with 124 positive PPT reactions, considered relevant in 56/223 patients (25.1%) and in 72/124 reactions (58.1%). Most reactions were caused by topical drugs (n = 33; 45.8%), such as ketoprofen or promethazine, and 7 (9.8%) by systemic drugs, such as hydrochlorothiazide and fenofibrate. 'Classical' ultraviolet filters were responsible for six positive PPT reactions whereas there was only three relevant PPT to the 'newer' UV filters. Patients' sunscreens/cosmetics or plant extracts caused 10 positive PPT each. Additional patch test reactions were observed, mostly to Tinosorb® M.
Conclusion: Contrary to the trend in ACD, most positive PPT reactions were caused by topical drugs, outweighing ultraviolet filters and cosmetics. We stress the low reactivity to the 'newer' UV filters included in the PPT series. PPT was occasionally positive in systemic drug photosensitivity, but overall PPT reactivity was low.
(© 2023 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd.)
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فهرسة مساهمة: Keywords: Tinosorb® M; UV filters; drug photosensitivity; fenofibrate; ketoprofen; photoallergic contact dermatitis; photopatch testing
المشرفين على المادة: 0 (Allergens)
0 (Sunscreening Agents)
تواريخ الأحداث: Date Created: 20230222 Date Completed: 20230508 Latest Revision: 20230508
رمز التحديث: 20240628
DOI: 10.1111/cod.14297
PMID: 36807918
قاعدة البيانات: MEDLINE
الوصف
تدمد:1600-0536
DOI:10.1111/cod.14297