دورية أكاديمية

Reduction-triggered Disassembly of Organic Cationic Nanorods Produces a Cysteine Protease Mimic (Miravet et al.).

التفاصيل البيبلوغرافية
العنوان: Reduction-triggered Disassembly of Organic Cationic Nanorods Produces a Cysteine Protease Mimic (Miravet et al.).
المؤلفون: Navarro-Barreda D; Department of Inorganic and Organic Chemistry, Universitat Jaume I, Av. Vicent Sos Baynat, s/n 12071, 12071, Castelló de la Plana, Spain., Angulo-Pachón CA; Department of Inorganic and Organic Chemistry, Universitat Jaume I, Av. Vicent Sos Baynat, s/n 12071, 12071, Castelló de la Plana, Spain., Galindo F; Department of Inorganic and Organic Chemistry, Universitat Jaume I, Av. Vicent Sos Baynat, s/n 12071, 12071, Castelló de la Plana, Spain., Miravet JF; Department of Inorganic and Organic Chemistry, Universitat Jaume I, Av. Vicent Sos Baynat, s/n 12071, 12071, Castelló de la Plana, Spain.
المصدر: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2023 May 11; Vol. 29 (27), pp. e202203764. Date of Electronic Publication: 2023 Mar 29.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Weinheim, Germany : Wiley-VCH
مواضيع طبية MeSH: Cysteine Proteases* , Nanotubes*, Cetrimonium ; Surface-Active Agents ; Cetrimonium Compounds ; Cations
مستخلص: The emergence of catalytic activity associated with a disassembly process is reported, reminiscent of complex biological systems. A cystine derivative with pendant imidazole groups self-assembles into cationic nanorods in the presence of the cationic surfactants cetylpyridinium chloride (CPC) or cetyltrimethylammonium bromide (CTAB). Disulfide reduction triggers nanorod disassembly and the generation of a simple cysteine protease mimic, which shows a dramatically improved catalytic efficiency in the hydrolysis of p-nitrophenyl acetate (PNPA).
(© 2023 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH.)
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معلومات مُعتمدة: RTI2018-096748-B-I00 Ministerio de Ciencia e Innovación; UJI-B2018-30 Universitat Jaume I
فهرسة مساهمة: Keywords: cysteine protease; enzyme mimic; self-assembled rods; stimuli-responsive nanoparticles
المشرفين على المادة: EC 3.4.- (Cysteine Proteases)
Z7FF1XKL7A (Cetrimonium)
0 (Surface-Active Agents)
0 (Cetrimonium Compounds)
0 (Cations)
تواريخ الأحداث: Date Created: 20230222 Date Completed: 20230515 Latest Revision: 20230515
رمز التحديث: 20230515
DOI: 10.1002/chem.202203764
PMID: 36808662
قاعدة البيانات: MEDLINE
الوصف
تدمد:1521-3765
DOI:10.1002/chem.202203764