دورية أكاديمية
أعرض في EDS

Long-term visual acuity outcomes following cataract surgery in eyes with ocular inflammatory disease.

التفاصيل البيبلوغرافية
العنوان: Long-term visual acuity outcomes following cataract surgery in eyes with ocular inflammatory disease.
المؤلفون: Gangaputra S; Vanderbilt Eye Institute, Nashville, Tennessee, USA sapna.gangaputra@vumc.org., Newcomb C; Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Armour R; Department of Ophthalmology, Oregon Health & Science University School of Medicine, Portland, Oregon, USA., Choi D; Public Health and Preventive Medicine, Oregon Health & Science University School of Medicine, Portland, Oregon, USA., Ying GS; Ophthalmology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Groth S; Vanderbilt Eye Institute, Nashville, Tennessee, USA., Begum H; Wilmer Eye Institute, Johns Hopkins Medicine School of Medicine, Baltimore, Maryland, USA., Fitzgerald T; Ophthalmology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Artornsombudh P; Ophthalmology, Somdech Phra Pinklao Hospital, Bangkok, Thailand.; Chulalongkorn University, Bangkok, Thailand., Daniel E; Ophthalmology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Bhatt N; Ophthalmology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Foster S; Massachusetts Eye Research and Surgery Institution, Waltham, Massachusetts, USA.; Sight for Souls, Fort Myers, Florida, USA., Jabs D; Wilmer Eye Institute, Johns Hopkins Medicine School of Medicine, Baltimore, Maryland, USA.; Center for Clinical Trials and Evidence Synthesis, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA., Levy-Clarke G; Laboratory of Immunology, National Eye Institute, Bethesda, Maryland, USA.; The Tampa Bay Uveitis Center, St Petersburg, Florida, USA., Nussenblatt R; Laboratory of Immunology, National Eye Institute, Bethesda, Maryland, USA., Rosenbaum JT; Department of Ophthalmology, Oregon Health & Science University School of Medicine, Portland, Oregon, USA.; Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, USA.; Legacy Devers Eye Institute at Good Samaritan Medical Center, Portland, Oregon, USA., Sen HN; Laboratory of Immunology, National Eye Institute, Bethesda, Maryland, USA., Suhler E; Department of Ophthalmology, Oregon Health & Science University School of Medicine, Portland, Oregon, USA.; Ophthalmology, Veterans Health Administration, Portland, Oregon, USA., Thorne J; Wilmer Eye Institute, Johns Hopkins Medicine School of Medicine, Baltimore, Maryland, USA.; Center for Clinical Trials and Evidence Synthesis, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA., Dreger K; Wilmer Eye Institute, Johns Hopkins Medicine School of Medicine, Baltimore, Maryland, USA.; Ophthalmology, Somdech Phra Pinklao Hospital, Bangkok, Thailand.; Center for Occupational Biostatistics and Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA.; Department of Population, Family, and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA., Buchanich J; Center for Occupational Biostatistics and Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA., Kempen JH; Sight for Souls, Fort Myers, Florida, USA.; Departments of Ophthalmology and Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.; Ophthalmology, Addis Ababa University School of Medicine, Addis Ababa, Ethiopia.; MCM Eye Unit, MyungSung Christian Medical Center General Hospital and MyungSung Medical School, Addis Ababa, Ethiopia.
مؤلفون مشاركون: Systemic Immunosuppressive Therapy for Eye Diseases (SITE) Research Group
المصدر: The British journal of ophthalmology [Br J Ophthalmol] 2024 Feb 21; Vol. 108 (3), pp. 380-385. Date of Electronic Publication: 2024 Feb 21.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 0421041 Publication Model: Electronic Cited Medium: Internet ISSN: 1468-2079 (Electronic) Linking ISSN: 00071161 NLM ISO Abbreviation: Br J Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Publication: Jan. 1992- : London : BMJ Pub. Group
Original Publication: 1917-Dec. 1991: London : British Medical Association
مواضيع طبية MeSH: Cataract*/complications , Cataract Extraction*/methods , Phacoemulsification* , Uveitis*/complications , Uveitis*/diagnosis , Uveitis*/surgery , Conjunctival Diseases*, Adult ; Humans ; Child ; Retrospective Studies ; Treatment Outcome ; Visual Acuity ; Vision Disorders
مستخلص: Purpose: To evaluate the long-term visual acuity (VA) outcome of cataract surgery in inflammatory eye disease.
Setting: Tertiary care academic centres.
Design: Multicentre retrospective cohort study.
Methods: A total of 1741 patients with non-infectious inflammatory eye disease (2382 eyes) who underwent cataract surgery while under tertiary uveitis management were included. Standardised chart review was used to gather clinical data. Multivariable logistic regression models with adjustment for intereye correlations were performed to evaluate the prognostic factors for VA outcomes. Main outcome measure was VA after cataract surgery.
Results: Uveitic eyes independent of anatomical location showed improved VA from baseline (mean 20/200) to within 3 months (mean 20/63) of cataract surgery and maintained through at least 5 years of follow-up (mean 20/63). Eyes that achieved 20/40 or better VA at 1 year were more likely to have scleritis (OR=1.34, p<0.0001) or anterior uveitis (OR=2.2, p<0.0001), VA 20/50 to 20/80 (OR 4.76 as compared with worse than 20/200, p<0.0001) preoperatively, inactive uveitis (OR=1.49, p=0.03), have undergone phacoemulsification (OR=1.45 as compared with extracapsular cataract extraction, p=0.04) or have had intraocular lens placement (OR=2.13, p=0.01). Adults had better VA immediately after surgery, with only 39% (57/146) paediatric eyes at 20/40 or better at 1 year.
Conclusions: Our results suggest that adult and paediatric eyes with uveitis typically have improved VA following cataract surgery and remain stable thereafter for at least 5 years.
Competing Interests: Competing interests: JTR: AbbVie (consultant); Gilead (consultant); Janssen (consultant); Eyevensys (consultant); UpToDate (author/royalties); Pfizer (financial support); Novartis (consultant); Roche (consultant); Alcon Research Institute (financial support); Horizon (financial support and consultant); Revolo (consultant); Neoleukin (consultant); Affibody (consultant); Celgene-Bristol Myers (Data Monitoring Committee); Eli Lilly (Clinical Endpoints Committee). GL-C: AbbVie (consultant, lecture fees); Allergan (grant support); Mallinckrodt (consultant, grant support); Sanofi (grant support, lecture fees). ES: Eyevensys (consultant); Santen (consultant); EyeGate (consultant, financial support); AbbVie (consultant, financial support); Clearside (consultant, financial support); EyePoint (consultant, financial support). SGa: Merit CRO (consultant); NEI (grant support); RPB (grant support). SGr: Olleyes (grant support). JT: AbbVie (consultant); ADVISE/MERIT, NEI (grant support); Gilead (consultant); Roche (consultant); Tarsier Pharma (equity owner); UpToDate (consultant). JHK: Gilead (consultant); Betaliq (equity owner); Tarsier Pharma (equity owner).
(© Author(s) (or their employer(s)) 2024. No commercial re-use. See rights and permissions. Published by BMJ.)
معلومات مُعتمدة: R21 EY032592 United States EY NEI NIH HHS; R01 EY014943 United States EY NEI NIH HHS
فهرسة مساهمة: Keywords: Epidemiology; Inflammation; Lens and zonules; Treatment Surgery; Vision
تواريخ الأحداث: Date Created: 20230222 Date Completed: 20240223 Latest Revision: 20240306
رمز التحديث: 20240307
DOI: 10.1136/bjo-2022-322236
PMID: 36810151
قاعدة البيانات: MEDLINE
الوصف
تدمد:1468-2079
DOI:10.1136/bjo-2022-322236