دورية أكاديمية
Passenger vehicle interior decontamination by low concentration hydrogen peroxide vapor following a wide area biological contamination incident.
| العنوان: | Passenger vehicle interior decontamination by low concentration hydrogen peroxide vapor following a wide area biological contamination incident. |
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| المؤلفون: | Oudejans L; U.S. Environmental Protection Agency, Office of Research and Development, Center for Environmental Solutions and Emergency Response, Research Triangle Park, NC 27711, USA., Richter W; Battelle Memorial Institute, Columbus, OH 43201, USA., Sunderman M; Battelle Memorial Institute, Columbus, OH 43201, USA., Calfee MW; U.S. Environmental Protection Agency, Office of Research and Development, Center for Environmental Solutions and Emergency Response, Research Triangle Park, NC 27711, USA., Mickelsen RL; U.S. Environmental Protection Agency, Office of Land and Emergency Management, Chemical, Biological, Radiological, and Nuclear Consequence Management Advisory Division, Research Triangle Park, NC 27711, USA., Hofacre K; Battelle Memorial Institute, Columbus, OH 43201, USA., Keyes P; Battelle Memorial Institute, Columbus, OH 43201, USA., Lee SD; U.S. Environmental Protection Agency, Office of Research and Development, Center for Environmental Solutions and Emergency Response, Research Triangle Park, NC 27711, USA. |
| المصدر: | Journal of applied microbiology [J Appl Microbiol] 2023 Mar 01; Vol. 134 (3). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 9706280 Publication Model: Print Cited Medium: Internet ISSN: 1365-2672 (Electronic) Linking ISSN: 13645072 NLM ISO Abbreviation: J Appl Microbiol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2022- : Oxford : Oxford University Press Original Publication: Oxford : Published for the Society for Applied Bacteriology by Blackwell Science, c1997- |
| مواضيع طبية MeSH: | Bacillus* , Bacillus anthracis*, Hydrogen Peroxide/pharmacology ; Decontamination/methods ; Spores, Bacterial |
| مستخلص: | Aims: To assess low concentration hydrogen peroxide (LCHP) (H2O2) vapor dispersed with a home humidifier for its ability to decontaminate vehicle interiors contaminated with Bacillus anthracis surrogate Bacillus atrophaeus spores. Methods and Results: Efficacy of a vaporized 3% H2O2 solution was evaluated for liquid volumes, on/off vehicle heating, ventilation, and air conditioning (HVAC) system operations, and temperatures that ranged from 5 to 27°C. Survival of the spores was assessed by quantification of remaining viable spores with efficacy quantified in terms of mean log10 reduction. Decontamination efficacy after the 6-day dwell time increased when the 3% H2O2 liquid volume was doubled, increasing from 4-of-10 to 10-of-10 nondetects (zero colonies counted using standard dilution and filter plating) inside the vehicle cabin. Recirculating cabin air through the HVAC system during decontamination decreased efficacy to 6-of-10 non-detects. While no 6-log10 reduction in viable spores was observed on the cabin filter with the cabin filter kept in place, a 6-log10 reduction was achieved after its removal and placement in the cabin during treatment. Conclusions: Results from this study allow for informed decisions on the use of LCHP vapor as an effective decontamination approach for vehicle interiors. (Published by Oxford University Press on behalf of Applied Microbiology International 2023.) |
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| معلومات مُعتمدة: | EPA999999 United States ImEPA Intramural EPA; United States EPA EPA |
| فهرسة مساهمة: | Keywords: bacillus anthracis; anthrax; bacterial spore; commercial off‐the‐shelf; remediation; sporicide; vaporous hydrogen peroxide; vehicle |
| المشرفين على المادة: | BBX060AN9V (Hydrogen Peroxide) |
| SCR Organism: | Bacillus atrophaeus |
| تواريخ الأحداث: | Date Created: 20230223 Date Completed: 20230313 Latest Revision: 20240302 |
| رمز التحديث: | 20240302 |
| مُعرف محوري في PubMed: | PMC10257935 |
| DOI: | 10.1093/jambio/lxad039 |
| PMID: | 36822624 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1365-2672 |
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| DOI: | 10.1093/jambio/lxad039 |