دورية أكاديمية
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Potential ecotoxicity of substrate-enriched zinc oxide nanoparticles to Physalaemus cuvieri tadpoles.

التفاصيل البيبلوغرافية
العنوان: Potential ecotoxicity of substrate-enriched zinc oxide nanoparticles to Physalaemus cuvieri tadpoles.
المؤلفون: Gomes AR; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Ecology, Conservation, and Biodiversity, Federal University of Uberlândia, Uberlândia, MG, Brazil; Post-Graduation Program in Agronomy, Goiano Federal Institute - Campus Rio Verde, GO, Brazil., Guimarães ATB; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil., Matos LP; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil., Silva AM; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil., Rodrigues ASL; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil., de Oliveira Ferreira R; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Conservation of Cerrado Natural Resources, Goiano Federal Institute, Urutaí, GO, Brazil., Islam ARMT; Begum Rokeya University, Department of Disaster Management, Rangpur 5404, Bangladesh., Rahman MM; Laboratory of Environmental Health and Ecotoxicology, Department of Environmental Sciences, Jahangirnagar University, Dhaka 1342, Bangladesh., Ragavendran C; Department of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, India., Kamaraj C; Interdisciplinary Institute of Indian System of Medicine (IIISM), Directorate of Research and Virtual Education, SRM Institute of Science and Technology (SRMIST), Kattankulathur 603203, Tamil Nadu, India., Silva FG; Post-Graduation Program in Agronomy, Goiano Federal Institute - Campus Rio Verde, GO, Brazil., Malafaia G; Laboratory of Toxicology Applied to the Environment, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Ecology, Conservation, and Biodiversity, Federal University of Uberlândia, Uberlândia, MG, Brazil; Post-Graduation Program in Conservation of Cerrado Natural Resources, Goiano Federal Institute, Urutaí, GO, Brazil; Post-Graduation Program in Biotechnology and Biodiversity, Federal University of Goiás, Goiânia, GO, Brazil; Brazilian Academy of Young Scientists (ABJC), Brazil. Electronic address: guilhermeifgoiano@gmail.com.
المصدر: The Science of the total environment [Sci Total Environ] 2023 May 15; Vol. 873, pp. 162382. Date of Electronic Publication: 2023 Feb 23.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0330500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1026 (Electronic) Linking ISSN: 00489697 NLM ISO Abbreviation: Sci Total Environ Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Amsterdam, Elsevier.
مواضيع طبية MeSH: Anura*/physiology , Nanoparticles*/toxicity , Zinc Oxide*/toxicity , Zinc Oxide*/metabolism, Animals ; Agriculture ; Antioxidants/metabolism ; Larva/metabolism
مستخلص: Although the ecotoxicological effects of ZnO nanoparticles (ZnO NPs) have already been reported in different taxa, little is known about their impacts on amphibians. Thus, we aimed to evaluate the potential effects of exposure of Physalaemus cuvieri tadpoles to substrates enriched with ZnO NPs (and with its ionic counterpart, Zn +2 , ZnCl 2 - both at 100 mg/kg) previously used in the cultivation of Panicum maximum (Guinea grass). We showed that although exposure for 21 days did not impact the survival, growth, and development of tadpoles, we noted an increase in the frequency of erythrocyte nuclear abnormalities in the "ZnCl 2 " and "ZnONP" groups, which was associated with suppression of antioxidant activity in the animals (inferred by SOD and CAT activity and DPPH free radical scavenging capacity). In the tadpoles of the "ZnONP" group, we also noticed a reduction in creatinine and bilirubin levels, alpha-amylase activity, and an increase in alkaline phosphatase activity. But the treatments did not alter the activity of the enzymes lactate dehydrogenase and gamma-glutamyl-transferase and total protein and carbohydrate levels. On the other hand, we report a cholinesterase and hypotriglyceridemic effect in the "ZnCl 2 " and "ZnONP" groups. Zn bioaccumulation in animals, from ZnO NPs, from Zn +2 released from them, or both, has been associated with causing these changes. Finally, principal component analysis (PCA) and the values of the "Integrated Biomarker Response" index revealed that the exposure of animals to substrates enriched with ZnO NPs caused more pronounced effects than those attributed to its ionic counterpart. Therefore, our study reinforces the need to consider the environmental risks of using these nanomaterials for agricultural purposes for amphibians.
Competing Interests: Declaration of competing interest We confirm that there are no known conflicts of interest associated with this work, and there has been no significant financial support for this work that could have influenced its outcome. Furthermore, we ensure that the manuscript has been read and approved by all named authors and that there are no other persons who satisfied the criteria for authorship but are not listed. We further confirm that all have approved the order of authors listed in the manuscript of us. Due care has been taken to ensure the integrity of the work.
(Copyright © 2023 Elsevier B.V. All rights reserved.)
فهرسة مساهمة: Keywords: Agricultural substrate; Amphibians; Biomarkers; Ecotoxicology; Nanomaterials
المشرفين على المادة: 0 (Antioxidants)
SOI2LOH54Z (Zinc Oxide)
تواريخ الأحداث: Date Created: 20230224 Date Completed: 20230821 Latest Revision: 20230821
رمز التحديث: 20230821
DOI: 10.1016/j.scitotenv.2023.162382
PMID: 36828072
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-1026
DOI:10.1016/j.scitotenv.2023.162382