دورية أكاديمية

Mesenchymal stem cell-released oncolytic virus: an innovative strategy for cancer treatment.

التفاصيل البيبلوغرافية
العنوان: Mesenchymal stem cell-released oncolytic virus: an innovative strategy for cancer treatment.
المؤلفون: Ghasemi Darestani N; Isfahan University of Medical Sciences, Isfahan, Iran., Gilmanova AI; Department of Prosthetic Dentistry of the I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation., Al-Gazally ME; College of Medicine, University of Al-Ameed, Karbala, Iraq., Zekiy AO; Department of Prosthetic Dentistry of the I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation., Ansari MJ; Department of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia., Zabibah RS; Medical Laboratory Technology Department, College of Medical Technology, The Islamic University, Najaf, Iraq., Jawad MA; Al-Nisour University College, Baghdad, Iraq., Al-Shalah SAJ; Medical Laboratories Techniques Department, Al-Mustaqbal University College, Babylon, Iraq., Rizaev JA; Department of Public Health and Healthcare Management, Rector, Samarkand State Medical University, Samarkand, Uzbekistan., Alnassar YS; The University of Mashreq, Baghdad, Iraq., Mohammed NM; Department of Pharmacy, Mazaya University College, Nasiriyah, Dhi Qar, Iraq., Mustafa YF; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Mosul, Mosul, 41001, Iraq., Darvishi M; Department of Aerospace and Subaquatic Medicine, Infectious Diseases and Tropical Medicine Research Center (IDTMRC), AJA University of Medical Sciences, Tehran, Iran. darvishi1349@gmail.com., Akhavan-Sigari R; Department of Neurosurgery, University Medical Center, Tuebingen, Germany.; Department of Health Care Management and Clinical Research, Collegium Humanum Warsaw Management University, Warsaw, Poland.
المصدر: Cell communication and signaling : CCS [Cell Commun Signal] 2023 Feb 24; Vol. 21 (1), pp. 43. Date of Electronic Publication: 2023 Feb 24.
نوع المنشور: Video-Audio Media; Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X (Electronic) Linking ISSN: 1478811X NLM ISO Abbreviation: Cell Commun Signal Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : BioMed Central, c2003-
مواضيع طبية MeSH: Oncolytic Viruses*/physiology , Oncolytic Virotherapy*/methods , Neoplasms*/pathology , Mesenchymal Stem Cells*/pathology, Humans ; Immunotherapy ; Tumor Microenvironment
مستخلص: Oncolytic viruses (OVs) infect, multiply, and finally remove tumor cells selectively, causing no damage to normal cells in the process. Because of their specific features, such as, the ability to induce immunogenic cell death and to contain curative transgenes in their genomes, OVs have attracted attention as candidates to be utilized in cooperation with immunotherapies for cancer treatment. This treatment takes advantage of most tumor cells' inherent tendency to be infected by certain OVs and both innate and adaptive immune responses are elicited by OV infection and oncolysis. OVs can also modulate tumor microenvironment and boost anti-tumor immune responses. Mesenchymal stem cells (MSC) are gathering interest as promising anti-cancer treatments with the ability to address a wide range of cancers. MSCs exhibit tumor-trophic migration characteristics, allowing them to be used as delivery vehicles for successful, targeted treatment of isolated tumors and metastatic malignancies. Preclinical and clinical research were reviewed in this study to discuss using MSC-released OVs as a novel method for the treatment of cancer. Video Abstract.
(© 2023. The Author(s).)
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فهرسة مساهمة: Keywords: Cancer treatment; Cellular carriers; Mesenchymal stem cell; Oncolytic virotherapy; Oncolytic virus
تواريخ الأحداث: Date Created: 20230224 Date Completed: 20230228 Latest Revision: 20230319
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC9960453
DOI: 10.1186/s12964-022-01012-0
PMID: 36829187
قاعدة البيانات: MEDLINE
الوصف
تدمد:1478-811X
DOI:10.1186/s12964-022-01012-0