دورية أكاديمية
أعرض في EDS

Safety, Feasibility and Efficacy of Lokomat ® and Armeo ® Spring Training in Deconditioned Paediatric, Adolescent and Young Adult Cancer Patients.

التفاصيل البيبلوغرافية
العنوان: Safety, Feasibility and Efficacy of Lokomat ® and Armeo ® Spring Training in Deconditioned Paediatric, Adolescent and Young Adult Cancer Patients.
المؤلفون: Atkinson M; Youth Cancer Service SA/NT, Royal Adelaide Hospital, Adelaide 5000, Australia., Tully A; Paediatric Rehabilitation Department, Women's and Children's Hospital, Adelaide 5006, Australia., Maher CA; Alliance for Research in Exercise, Nutrition and Activity (ARENA), Allied Health and Human Performance, University of South Australia, Adelaide 5000, Australia., Innes-Wong C; Paediatric Rehabilitation Department, Women's and Children's Hospital, Adelaide 5006, Australia., Russo RN; Paediatric Rehabilitation Department, Women's and Children's Hospital, Adelaide 5006, Australia.; School of Medicine, Flinders University, Adelaide 5042, Australia., Osborn MP; Youth Cancer Service SA/NT, Royal Adelaide Hospital, Adelaide 5000, Australia.; Department of Haematology and Oncology, Women's and Children's Hospital, Adelaide 5006, Australia.; Adelaide Medical School, University of Adelaide, Adelaide 5000, Australia.
المصدر: Cancers [Cancers (Basel)] 2023 Feb 16; Vol. 15 (4). Date of Electronic Publication: 2023 Feb 16.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI
مستخلص: Background: Rehabilitation robotics is a field of study which aims to understand and augment rehabilitation through the use of robotics devices.
Objective: This proof of concept study aimed to test the safety (no. adverse events, incidence of infection), feasibility (program demand, adherence, participant satisfaction) and efficacy (Peak Oxygen uptake (VO 2peak ), 6-min walk test, gait speeds, Canadian Occupational Performance Measure, quality of life) of Lokomat ® and Armeo ® Spring training in children and adolescents and young adults (AYAs) during or soon after cancer treatment.
Method: This was a 6-week single arm pre-post study. Cancer patients with significant musculoskeletal, neurological, gait and/or upper limb deficiency aged 5 to 25 years were recruited. The rehabilitation program included access to two robotic orthoses: the Lokomat ® and/or Armeo ® Spring. Robotic devices utilised real-time biofeedback and computer games to engage and guide participants through a repetitive functional range of movement aimed at improving functional deficiencies. Progressive increases in exercise intensity and duration were encouraged.
Results: Twentey-eight participants were approached for study; twenty-one consented. Seventy-six percent completed the six-week intervention with an overall adherence of 83%. The mean participant satisfaction score was 8.8/10. Forty-nine adverse events were recorded throughout the course of the study, forty-five grade 1, three grade 2 and one grade 3. No adverse events led to withdrawal from the study. Preliminary efficacy results indicate large beneficial effects on VO 2peak (r = 0.63), 10 m comfortable pace walk (r = 0.51) and maximal pace walk (r = 0.60), 6-min walk test (r = 0.60), maximal back and leg strength (r = 0.71), trunk flexibility (r = 0.60), The European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ C30) (r = 0.61), Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT F) r = 0.53 and the Canadian Occupational Performance Measure, satisfaction (r = 0.88) and performance scores (r = 0.83), and moderate beneficial effects on Leisure Score Index (LSI) (r = 0.30).
Conclusion: Our results suggest that Lokomat ® and Armeo ® Spring training is safe and feasible for use in children and AYAs who are currently undergoing or have recently completed cancer therapy. A larger controlled trial investigating the efficacy of robotics rehabilitation in this cohort is warranted.
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معلومات مُعتمدة: 19/10689987 Channel 7 Children's Research Foundation
فهرسة مساهمة: Keywords: VO2peak; adolescent and young adult; cancer; child; deconditioned; exercise; robot-based therapy
تواريخ الأحداث: Date Created: 20230225 Latest Revision: 20230228
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9954270
DOI: 10.3390/cancers15041250
PMID: 36831593
قاعدة البيانات: MEDLINE
الوصف
تدمد:2072-6694
DOI:10.3390/cancers15041250