دورية أكاديمية
Safety, Feasibility and Efficacy of Lokomat ® and Armeo ® Spring Training in Deconditioned Paediatric, Adolescent and Young Adult Cancer Patients.
العنوان: | Safety, Feasibility and Efficacy of Lokomat ® and Armeo ® Spring Training in Deconditioned Paediatric, Adolescent and Young Adult Cancer Patients. |
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المؤلفون: | Atkinson M; Youth Cancer Service SA/NT, Royal Adelaide Hospital, Adelaide 5000, Australia., Tully A; Paediatric Rehabilitation Department, Women's and Children's Hospital, Adelaide 5006, Australia., Maher CA; Alliance for Research in Exercise, Nutrition and Activity (ARENA), Allied Health and Human Performance, University of South Australia, Adelaide 5000, Australia., Innes-Wong C; Paediatric Rehabilitation Department, Women's and Children's Hospital, Adelaide 5006, Australia., Russo RN; Paediatric Rehabilitation Department, Women's and Children's Hospital, Adelaide 5006, Australia.; School of Medicine, Flinders University, Adelaide 5042, Australia., Osborn MP; Youth Cancer Service SA/NT, Royal Adelaide Hospital, Adelaide 5000, Australia.; Department of Haematology and Oncology, Women's and Children's Hospital, Adelaide 5006, Australia.; Adelaide Medical School, University of Adelaide, Adelaide 5000, Australia. |
المصدر: | Cancers [Cancers (Basel)] 2023 Feb 16; Vol. 15 (4). Date of Electronic Publication: 2023 Feb 16. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI |
مستخلص: | Background: Rehabilitation robotics is a field of study which aims to understand and augment rehabilitation through the use of robotics devices. Objective: This proof of concept study aimed to test the safety (no. adverse events, incidence of infection), feasibility (program demand, adherence, participant satisfaction) and efficacy (Peak Oxygen uptake (VO Method: This was a 6-week single arm pre-post study. Cancer patients with significant musculoskeletal, neurological, gait and/or upper limb deficiency aged 5 to 25 years were recruited. The rehabilitation program included access to two robotic orthoses: the Lokomat ® and/or Armeo ® Spring. Robotic devices utilised real-time biofeedback and computer games to engage and guide participants through a repetitive functional range of movement aimed at improving functional deficiencies. Progressive increases in exercise intensity and duration were encouraged. Results: Twentey-eight participants were approached for study; twenty-one consented. Seventy-six percent completed the six-week intervention with an overall adherence of 83%. The mean participant satisfaction score was 8.8/10. Forty-nine adverse events were recorded throughout the course of the study, forty-five grade 1, three grade 2 and one grade 3. No adverse events led to withdrawal from the study. Preliminary efficacy results indicate large beneficial effects on VO Conclusion: Our results suggest that Lokomat ® and Armeo ® Spring training is safe and feasible for use in children and AYAs who are currently undergoing or have recently completed cancer therapy. A larger controlled trial investigating the efficacy of robotics rehabilitation in this cohort is warranted. |
References: | Cancers (Basel). 2021 Dec 24;14(1):. (PMID: 35008246) J Clin Oncol. 2020 Jan 1;38(1):29-42. (PMID: 31622133) Am J Respir Crit Care Med. 2002 Jul 1;166(1):111-7. (PMID: 12091180) Cancer Nurs. 2016 Mar-Apr;39(2):134-43. (PMID: 25950583) PLoS One. 2017 May 19;12(5):e0177965. (PMID: 28542374) Ergonomics. 1994 Jan;37(1):79-86. (PMID: 8112285) Am J Occup Ther. 2021 Nov 1;75(6):. (PMID: 34817593) J Neuroeng Rehabil. 2017 Jul 14;14(1):76. (PMID: 28705170) Clin Rehabil. 2022 Jul;36(7):873-882. (PMID: 35331027) Pilot Feasibility Stud. 2016 May 20;2:25. (PMID: 27965844) J Neuroeng Rehabil. 2017 Jan 5;14(1):1. (PMID: 28057016) J Neuroeng Rehabil. 2022 Apr 22;19(1):40. (PMID: 35459246) Front Robot AI. 2020 Nov 16;7:557606. (PMID: 33501319) Knee. 2009 Oct;16(5):405-8. (PMID: 19269182) Med Sci Sports Exerc. 2010 Jul;42(7):1409-26. (PMID: 20559064) Biomed Eng Online. 2021 Sep 6;20(1):89. (PMID: 34488777) Support Care Cancer. 2015 Feb;23(2):501-10. (PMID: 25294658) Neurologia. 2013 Jun;28(5):261-7. (PMID: 22727271) J Clin Oncol. 2016 May 10;34(14):1626-33. (PMID: 26951318) Front Neurol. 2021 Jul 06;12:661815. (PMID: 34295298) J Clin Oncol. 2012 Dec 20;30(36):4458-61. (PMID: 23045598) BMC Med Res Methodol. 2015 Aug 12;15:60. (PMID: 26264621) Epidemiol Rev. 2017 Jan 1;39(1):71-92. (PMID: 28453622) J Sci Med Sport. 2019 Nov;22(11):1175-1199. (PMID: 31277921) Cochrane Database Syst Rev. 2016 Mar 31;3:CD008796. (PMID: 27030386) Eur J Phys Rehabil Med. 2021 Oct;57(5):841-849. (PMID: 34547886) JMIR Cancer. 2016 May 24;2(1):e6. (PMID: 28410184) Oncologist. 2011;16(1):112-20. (PMID: 21212429) BMJ. 2014 Mar 07;348:g1687. (PMID: 24609605) Sensors (Basel). 2022 Jun 08;22(12):. (PMID: 35746117) Int J Sports Med. 2014 Dec;35(13):1134-7. (PMID: 24995960) J Clin Oncol. 2009 May 10;27(14):2382-9. (PMID: 19332713) Ann Oncol. 2014 May;25(5):947-58. (PMID: 24401927) Children (Basel). 2022 Jun 02;9(6):. (PMID: 35740761) Lancet Oncol. 2009 Jun;10(6):598-605. (PMID: 19482248) BMJ. 2012 Jan 30;344:e70. (PMID: 22294757) Am J Respir Crit Care Med. 2003 Jan 15;167(2):211-77. (PMID: 12524257) Health Qual Life Outcomes. 2016 Jun 07;14:87. (PMID: 27267486) Respir Care. 2014 Apr;59(4):531-7. (PMID: 23983271) Pediatr Blood Cancer. 2021 Jan;68(1):e28751. (PMID: 33063932) Eur J Pediatr. 2010 Mar;169(3):281-7. (PMID: 19526369) Nat Rev Clin Oncol. 2012 Mar 06;9(5):288-96. (PMID: 22392097) J Adolesc Young Adult Oncol. 2019 Oct;8(5):512-524. (PMID: 31090475) Mult Scler Relat Disord. 2020 Mar 3;41:102034. (PMID: 32200337) |
معلومات مُعتمدة: | 19/10689987 Channel 7 Children's Research Foundation |
فهرسة مساهمة: | Keywords: VO2peak; adolescent and young adult; cancer; child; deconditioned; exercise; robot-based therapy |
تواريخ الأحداث: | Date Created: 20230225 Latest Revision: 20230228 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC9954270 |
DOI: | 10.3390/cancers15041250 |
PMID: | 36831593 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2072-6694 |
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DOI: | 10.3390/cancers15041250 |