دورية أكاديمية
أعرض في EDS

Utility of Opportunistic Infections, Joints' Involvement and Accuracy of Various Screening Tests to Diagnose Rheumatoid Arthritis Patients.

التفاصيل البيبلوغرافية
العنوان: Utility of Opportunistic Infections, Joints' Involvement and Accuracy of Various Screening Tests to Diagnose Rheumatoid Arthritis Patients.
المؤلفون: Ahmad A; Department of Community Medicine, IIMS&R, Integral University, Lucknow 226026, India., Khan A; Department of Physiotherapy, Integral University, Lucknow 226026, India., Khan AR; Department of Physiotherapy, Integral University, Lucknow 226026, India., Ahmed H; Department of Medical Rehabilitation Science, College of Applied Medical Sciences, Najran University, Najran 55461, Saudi Arabia., Alajam RA; Department of Physical Therapy, College of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi Arabia., Alshehri MM; Department of Physical Therapy, College of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi Arabia., Ganesan BBM; Department of Physical Therapy, College of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi Arabia., Dayah SJA; Department of Physical Therapy, College of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi Arabia., Shaphe MA; Department of Physical Therapy, College of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi Arabia., Alameer AH; Department of Physical Therapy, College of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi Arabia., Esht V; Department of Physical Therapy, College of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi Arabia.
المصدر: Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2023 Feb 14; Vol. 59 (2). Date of Electronic Publication: 2023 Feb 14.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 9425208 Publication Model: Electronic Cited Medium: Internet ISSN: 1648-9144 (Electronic) Linking ISSN: 1010660X NLM ISO Abbreviation: Medicina (Kaunas) Subsets: MEDLINE
أسماء مطبوعة: Publication: 2018- : Basel, Switzerland : MDPI
Original Publication: Kaunas : Lietuvos gydytojų sąjunga
مواضيع طبية MeSH: Arthritis, Rheumatoid*/diagnosis , Opportunistic Infections*, Humans ; Cross-Sectional Studies ; Rheumatoid Factor
مستخلص: Background and Objectives : Rheumatoid Arthritis (RA) is an auto-immune disease in which the body mistakenly considers some parts of its own system as pathogens and attacks them. Prevalence is approximately 0.75% in India. About 40% of the diseased become work disabled within 5 years from the onset of symptoms. The objective of this paper is to assess the sign/symptoms, joints' involvement, difficulties in daily activities and screening accuracy of serology tests of clinically suspected RA patients. Material and Methods : A cross-sectional cohort study design was conducted on two hundred ninety clinically suspected subjects who were referred by different OPDs of hospitals for screening. The profiles of study subjects were carried through a semi-structured, pre-tested schedule method. About 2 mL of blood samples were collected in a plain vial from each patient and tested for diagnostic tests RF, CRP and AntiCCP by using RF-Latex, CRP Latex and ELISA method, respectively, by the laboratory persons. Results : Joint pain shows to be a leading problem in RA as compared to other signs and symptoms. The majority of the study subjects suffer from knee problems (62%). Approximately equal numbers of RA-positive cases were screened by RF and AntiCCP tests. The CRP test screened about one-third of cases. CRP+ AntiCCP, RF+ AntiCCP and RF + CRP all have good sensitivity, and RF+ AntiCCP + CRP has a very high sensitivity for diagnosing RA. Conclusions : This study found that a substantiation of a major proportion of clinically suspected RA patients were suffering from knee pain. Predication of AntiCCP increased the possibility for the diagnosis of RA. However, RF was also moderately related to the diagnosis of RA, and the combination of both tests was more valuable.
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فهرسة مساهمة: Keywords: joint pain; rheumatoid arthritis; sign symptoms
المشرفين على المادة: 9009-79-4 (Rheumatoid Factor)
تواريخ الأحداث: Date Created: 20230225 Date Completed: 20230228 Latest Revision: 20230301
رمز التحديث: 20230301
مُعرف محوري في PubMed: PMC9964989
DOI: 10.3390/medicina59020367
PMID: 36837567
قاعدة البيانات: MEDLINE
الوصف
تدمد:1648-9144
DOI:10.3390/medicina59020367