دورية أكاديمية
Evaluation of Radiographic Outcomes of Alveolar Graft Associated with Premaxillary Osteotomy Performed with rhBMP-2.
| العنوان: | Evaluation of Radiographic Outcomes of Alveolar Graft Associated with Premaxillary Osteotomy Performed with rhBMP-2. |
|---|---|
| المؤلفون: | Resende Leal C; Department of Maxillofacial Surgery, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil., Rocha LA; Postgraduate at the Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil., Carvalho RM; Department of Maxillofacial Surgery, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil., Faco RAS; Department of Maxillofacial Surgery, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil., Alonso N; Department of Craniofacial Surgery, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil., Ozawa TO; Department of Orthodontics, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil., Tonello C; Department of Craniofacial Surgery, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, SP, Brazil. |
| المصدر: | The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association [Cleft Palate Craniofac J] 2024 Jul; Vol. 61 (7), pp. 1195-1201. Date of Electronic Publication: 2023 Feb 27. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: SAGE Publications in Association with American Cleft Palate-Craniofacial Association Country of Publication: United States NLM ID: 9102566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-1569 (Electronic) Linking ISSN: 10556656 NLM ISO Abbreviation: Cleft Palate Craniofac J Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2018- : [Thousand Oaks, CA] : SAGE Publications in Association with American Cleft Palate-Craniofacial Association Original Publication: Pittsburgh, PA : The Association, [1991- |
| مواضيع طبية MeSH: | Alveolar Bone Grafting*/methods , Bone Morphogenetic Protein 2*/therapeutic use , Cleft Lip*/surgery , Cleft Lip*/diagnostic imaging , Cleft Palate*/surgery , Cleft Palate*/diagnostic imaging , Recombinant Proteins*/administration & dosage , Recombinant Proteins*/therapeutic use, Adolescent ; Female ; Humans ; Male ; Bone Transplantation/methods ; Cross-Sectional Studies ; Ilium/transplantation ; Ilium/diagnostic imaging ; Osteotomy/methods ; Transforming Growth Factor beta/therapeutic use ; Treatment Outcome |
| مستخلص: | Objective: To evaluate the influence of filling material and timing of surgery on radiograph outcomes of alveolar grafting with premaxillary osteotomy. The null hypothesis was that radiographic outcomes would be similar with both rhBMP-2 (rhBMP-2G) and cancellous bone from the iliac crest (IG), regardless of the timing of surgery. Design: Cross-sectional study with consecutive sampling of 56 periapical or occlusal radiographs taken 12 months after surgery. Setting: A single tertiary craniofacial center. Patients/participants: Twenty-eight patients with complete bilateral cleft lip and palate and mean age of 13 years. The individuals underwent bilateral alveolar grafting associated with premaxillary osteotomy (AG + PO) with rhBMP-2 or cancellous bone from the iliac crest. Interventions: Experienced maxillofacial surgeons used the same surgical technique in both groups. AG + PO were assigned as success or failure by 3 blinded raters based on modified Bergland and SWAG scales. Main Outcome Measures: The influence of filling materials and timing of surgery on radiographic outcomes was verified by Fisher's exact test and chi-square test ( P < .05). Results: There was no significance variation between the mean age of participants in the rhBMP-2G and IG ( P = .471). Scales showed almost perfect reliability (agreement rate = 96.4%; K = 0.85). rhBMP-2G and IG had similar success rates with modified Bergland scale (85.7% and 82.1%) and SWAG scale (92.9% and 82.1%), respectively. However, only modified Bergland scale found influence of age on radiographic outcomes ( P = .025). Conclusions: AG + PO performed with rhBMP-2 and iliac crest bone showed similar radiographic success rates, regardless of the timing of surgery. Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. |
| فهرسة مساهمة: | Keywords: bone grafting; bone regeneration; midfacial growth; nonsyndromic clefting; orthodontics; osteotomy; psychosocial adjustment |
| المشرفين على المادة: | 0 (Bone Morphogenetic Protein 2) 0 (recombinant human bone morphogenetic protein-2) 0 (Recombinant Proteins) 0 (Transforming Growth Factor beta) |
| تواريخ الأحداث: | Date Created: 20230227 Date Completed: 20240605 Latest Revision: 20240613 |
| رمز التحديث: | 20240613 |
| DOI: | 10.1177/10556656231160396 |
| PMID: | 36843505 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1545-1569 |
|---|---|
| DOI: | 10.1177/10556656231160396 |