دورية أكاديمية
أعرض في EDS

The role of glial cells in Zika virus-induced neurodegeneration.

التفاصيل البيبلوغرافية
العنوان: The role of glial cells in Zika virus-induced neurodegeneration.
المؤلفون: Quincozes-Santos A; Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.; Programa de Pós-Graduação em Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil., Bobermin LD; Programa de Pós-Graduação em Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil., Costa NLF; Programa de Pós-Graduação em Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil., Thomaz NK; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil., Almeida RRS; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil., Beys-da-Silva WO; Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil., Santi L; Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil., Rosa RL; Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil., Capra D; Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Coelho-Aguiar JM; Laboratório de Morfogênese Celular, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., DosSantos MF; Laboratório de Propriedades Mecânicas e Biologia Celular, Faculdade de Odontologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Heringer M; Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Cirne-Lima EO; Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil., Guimarães JA; Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil., Schuler-Faccini L; Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil., Gonçalves CA; Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.; Programa de Pós-Graduação em Neurociências, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil., Moura-Neto V; Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.; Laboratório de Morfogênese Celular, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Souza DO; Departamento de Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.; Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
المصدر: Glia [Glia] 2023 Aug; Vol. 71 (8), pp. 1791-1803. Date of Electronic Publication: 2023 Mar 03.
نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 8806785 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-1136 (Electronic) Linking ISSN: 08941491 NLM ISO Abbreviation: Glia Subsets: MEDLINE
أسماء مطبوعة: Publication: New York, NY : Wiley-Liss
Original Publication: New York : Alan R. Liss, Inc., c1988-
مواضيع طبية MeSH: Zika Virus*/physiology , Zika Virus Infection*/complications , Zika Virus Infection*/drug therapy , Zika Virus Infection*/pathology, Humans ; Neuroglia/metabolism ; Central Nervous System/metabolism ; Brain/metabolism
مستخلص: Zika virus (ZIKV) is a strongly neurotropic flavivirus whose infection has been associated with microcephaly in neonates. However, clinical and experimental evidence indicate that ZIKV also affects the adult nervous system. In this regard, in vitro and in vivo studies have shown the ability of ZIKV to infect glial cells. In the central nervous system (CNS), glial cells are represented by astrocytes, microglia, and oligodendrocytes. In contrast, the peripheral nervous system (PNS) constitutes a highly heterogeneous group of cells (Schwann cells, satellite glial cells, and enteric glial cells) spread through the body. These cells are critical in both physiological and pathological conditions; as such, ZIKV-induced glial dysfunctions can be associated with the development and progression of neurological complications, including those related to the adult and aging brain. This review will address the effects of ZIKV infection on CNS and PNS glial cells, focusing on cellular and molecular mechanisms, including changes in the inflammatory response, oxidative stress, mitochondrial dysfunction, Ca 2+ and glutamate homeostasis, neural metabolism, and neuron-glia communication. Of note, preventive and therapeutic strategies that focus on glial cells may emerge to delay and/or prevent the development of ZIKV-induced neurodegeneration and its consequences.
(© 2023 Wiley Periodicals LLC.)
References: Allaman, I., Bélanger, M., & Magistretti, P. J. (2011). Astrocyte-neuron metabolic relationships: For better and for worse. Trends in Neurosciences, 34, 76-87.
Almeida, L. T., Ferraz, A. C., da Silva Caetano, C. C., da Silva Menegatto, M. B., dos Santos Pereira Andrade, A. C., Lima, R. L. S., Camini, F. C., Pereira, S. H., da Silva Pereira, K. Y., de Mello Silva, B., Perucci, L. O., Talvani, A., de Magalhães, J. C., & de Brito Magalhães, C. L. (2020). Zika virus induces oxidative stress and decreases antioxidant enzyme activities in vitro and in vivo. Virus Research, 286, 198084.
Alves, V. S., Leite-Aguiar, R., da Silva, J. P., Coutinho-Silva, R., & Savio, L. E. B. (2020). Purinergic signaling in infectious diseases of the central nervous system. Brain, Behavior, and Immunity, 89, 480-490.
Alves-Leon, S. V., da Lima, M. R., PCG, N., LMC, C., Rabelo, K., Nogueira, R. M. R., de Bruycker-Nogueira, F., de Azeredo, E. L., Bahia, P. R., Rueda Lopes, F. C., de Souza JPB, M., Fontes-Dantas, F. L., Paes, M. V., Lemos, E. R., & Santos, F. B. (2019). Zika virus found in brain tissue of a multiple sclerosis patient undergoing an acute disseminated encephalomyelitis-like episode. Multiple Sclerosis, 25, 427-430.
Bélanger, M., Allaman, I., & Magistretti, P. J. (2011). Brain energy metabolism: Focus on astrocyte-neuron metabolic cooperation. Cell Metabolism, 14, 724-738.
Beys-da-Silva, W. O., Quincozes-Santos, A., Tureta, E. F., Rosa, R. L., Berger, M., Bobermin, L. D., Souza, D. O., Guimarães, J. A., & Santi, L. (2020). Association between Zika virus and future neurological diseases. Journal of the Neurological Sciences, 409, 116617.
Beys-da-Silva, W. O., Rosa, R. L., Santi, L., Berger, M., Park, S. K., Campos, A. R., Terraciano, P., Varela, A. P. M., Teixeira, T. F., Roehe, P. M., Quincozes-Santos, A., Yates, J. R., Souza, D. O., Cirne-Lima, E. O., & Guimarães, J. A. (2019). Zika virus infection of human mesenchymal stem cells promotes differential expression of proteins linked to several neurological diseases. Molecular Neurobiology, 56, 4708-4717.
Bhat, A. H., Dar, K. B., Anees, S., Zargar, M. A., Masood, A., Sofi, M. A., & Ganie, S. A. (2015). Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight. Biomedicine & Pharmacotherapy, 74, 101-110.
Bido-Medina, R., Wirsich, J., Rodríguez, M., Oviedo, J., Miches, I., Bido, P., Tusen, L., Stoeter, P., & Sadaghiani, S. (2018). Impact of Zika virus on adult human brain structure and functional organization. Annals of Clinical Translational Neurology, 5, 752-762.
Bobermin, L. D., Quincozes-Santos, A., Santos, C. L., Varela, A. P. M., Teixeira, T. F., Wartchow, K. M., Lissner, L. J., da Silva, A., Thomaz, N. K., Santi, L., Beys-da-Silva, W. O., Roehe, P. M., Sesterheim, P., Guimarães, J. A., Gonçalves, C.-A., & Souza, D. O. (2020). Zika virus exposure affects neuron-glia communication in the hippocampal slices of adult rats. Scientific Reports, 10, 21604.
Brison, E., Jacomy, H., Desforges, M., & Talbot, P. J. (2014). Novel treatment with neuroprotective and antiviral properties against a neuroinvasive human respiratory virus. Journal of Virology, 88, 1548-1563.
Carricondo, F., & Romero-Gómez, B. (2019). The cochlear spiral ganglion neurons: The auditory portion of the VIII nerve. The Anatomical Record, 302, 463-471.
Carteaux, G., Maquart, M., Bedet, A., Contou, D., Brugières, P., Fourati, S., Cleret de Langavant, L., de Broucker, T., Brun-Buisson, C., Leparc-Goffart, I., & Mekontso, D. A. (2016). Zika virus associated with meningoencephalitis. The New England Journal of Medicine, 374, 1595-1596.
CHA, B.-M., Neto, A. M., Calvet, G. A., Kara, E. O., Lacerda, M. V. G., da Castilho, M. C., Ströher, U., Antunes de Brito, C. A., Modjarrad, K., Broutet, N., Brasil, P., Bispo de Filippis, A. M., Franca, R. F. O., & ZIKABRA Study Team. (2019). Zika virus in rectal swab samples. Emerging Infectious Diseases, 25, 951-954.
Chen, J., Yang, Y., Yang, Y., Zou, P., Chen, J., He, Y., Shui, S., Cui, Y., Bai, R., Liang, Y., Hu, Y., Jiang, B., Lu, L., Zhang, X., Liu, J., & Xu, J. (2018). AXL promotes Zika virus infection in astrocytes by antagonizing type I interferon signalling. Nature Microbiology, 3, 302-309.
Costa, V. V., Del Sarto, J. L., Rocha, R. F., Silva, F. R., Doria, J. G., Olmo, I. G., Marques, R. E., Queiroz-Junior, C. M., Foureaux, G., Araújo, J. M. S., Cramer, A., Real, A. L. C. V., Ribeiro, L. S., Sardi, S. I., Ferreira, A. J., Machado, F. S., de Oliveira, A. C., Teixeira, A. L., Nakaya, H. I., … Teixeira, M. M. (2017). N-methyl-d-aspartate (NMDA) receptor blockade prevents neuronal death induced by Zika virus. Infection, mBio 8, e00350-e00317.
Coulter, D. A., & Eid, T. (2012). Astrocytic regulation of glutamate homeostasis in epilepsy. Glia, 60, 1215-1226.
Cumberworth, S. L., Barrie, J. A., Cunningham, M. E., de Figueiredo, D. P. G., Schultz, V., Wilder-Smith, A. J., Brennan, B., Pena, L. J., de Oliveira, F., França, R., Linington, C., Barnett, S. C., Willison, H. J., Kohl, A., & Edgar, J. M. (2017). Zika virus tropism and interactions in myelinating neural cell cultures: CNS cells and myelin are preferentially affected. Acta Neuropathologica Communications, 5, 50.
de Barbosa, M. H. M., de Magalhães-Barbosa, M. C., Robaina, J. R., Prata-Barbosa, A., de de Lima, M. A. M. T., & da Cunha, A. J. L. A. (2019). Auditory findings associated with Zika virus infection: An integrative review. Brazilian Journal of Otorhinolaryngology, 85, 642-663.
Nem de Oliveira Souza, I., Frost, P. S., França, J. V., Nascimento-Viana, J. B., Neris, R. L. S., Freitas, L., Pinheiro, D. J. L. L., Nogueira, C. O., Neves, G., Chimelli, L., De Felice, F. G., Cavalheiro, É. A., Ferreira, S. T., Assunção-Miranda, I., Figueiredo, C. P., Da Poian, A. T., & Clarke, J. R. (2018). Acute and chronic neurological consequences of early-life Zika virus infection in mice. Science Translational Medicine, 10, eaar2749.
Dehhaghi, M., Kazemi Shariat Panahi, H., & Guillemin, G. J. (2018). Microorganisms' footprint in neurodegenerative diseases. Frontiers in Cellular Neuroscience, 12, 466.
Devhare, P., Meyer, K., Steele, R., Ray, R. B., & Ray, R. (2017). Zika virus infection dysregulates human neural stem cell growth and inhibits differentiation into neuroprogenitor cells. Cell Death & Disease, 8, e3106.
Dhiman, G., Abraham, R., & Griffin, D. E. (2019). Human Schwann cells are susceptible to infection with Zika and yellow fever viruses, but not dengue virus. Scientific Reports, 9, 9951.
Duan, S., Anderson, C. M., Keung, E. C., Chen, Y., Chen, Y., & Swanson, R. A. (2003). P2X7 receptor-mediated release of excitatory amino acids from astrocytes. The Journal of Neuroscience, 23, 1320-1328.
Ekberg, J. A. K., & St john, J. A. (2014). Crucial roles for olfactory ensheathing cells and olfactory mucosal cells in the repair of damaged neural tracts: Neural regeneration using olfactory cells. The Anatomical Record, 297, 121-128.
Enlow, W., Bordeleau, M., Piret, J., Ibáñez, F. G., Uyar, O., Venable, M.-C., Goyette, N., Carbonneau, J., Tremblay, M.-E., & Boivin, G. (2021). Microglia are involved in phagocytosis and extracellular digestion during Zika virus encephalitis in young adult immunodeficient mice. Journal of Neuroinflammation, 18, 178.
Ferrari-Marinho, T., De Marchi, L. R., & Caboclo, L. O. (2022). Clinical neurophysiology of Zika virus encephalitis. Journal of Clinical Neurophysiology, 39, 259-264.
Ficker, C., Rozmer, K., Kató, E., Andó, R. D., Schumann, L., Krügel, U., Franke, H., Sperlágh, B., Riedel, T., & Illes, P. (2014). Astrocyte-neuron interaction in the substantia gelatinosa of the spinal cord dorsal horn via P2X7 receptor-mediated release of glutamate and reactive oxygen species. Glia, 62, 1671-1686.
Figueiredo, C. P., Barros-Aragão, F. G. Q., Neris, R. L. S., Frost, P. S., Soares, C., Souza, I. N. O., Zeidler, J. D., Zamberlan, D. C., de Sousa, V. L., Souza, A. S., Guimarães, A. L. A., Bellio, M., Marcondes de Souza, J., Alves-Leon, S. V., Neves, G. A., Paula-Neto, H. A., Castro, N. G., De Felice, F. G., Assunção-Miranda, I., … Ferreira, S. T. (2019). Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice. Nature Communications, 10, 3890.
Fontaine, K. A., Sanchez, E. L., Camarda, R., & Lagunoff, M. (2015). Dengue virus induces and requires glycolysis for optimal replication. Journal of Virology, 89, 2358-2366.
França, G. V. A., Schuler-Faccini, L., Oliveira, W. K., Henriques, C. M. P., Carmo, E. H., Pedi, V. D., Nunes, M. L., Castro, M. C., Serruya, S., Silveira, M. F., Barros, F. C., & Victora, C. G. (2016). Congenital Zika virus syndrome in Brazil: A case series of the first 1501 livebirths with complete investigation. Lancet, 388, 891-897.
Gaburro, J., Bhatti, A., Sundaramoorthy, V., Dearnley, M., Green, D., Nahavandi, S., Paradkar, P. N., & Duchemin, J.-B. (2018). Zika virus-induced hyper excitation precedes death of mouse primary neuron. Virology Journal, 15, 79.
Garber, C., Soung, A., Vollmer, L. L., Kanmogne, M., Last, A., Brown, J., & Klein, R. S. (2019). T cells promote microglia-mediated synaptic elimination and cognitive dysfunction during recovery from neuropathogenic flaviviruses. Nature Neuroscience, 22, 1276-1288.
García-Marín, V., García-López, P., & Freire, M. (2007). Cajal's contributions to glia research. Trends in Neurosciences, 30, 479-487.
Gasco, S., & Muñoz-Fernández, M. Á. (2020). A review on the current knowledge on ZIKV infection and the interest of organoids and nanotechnology on development of effective therapies against Zika infection. IJMS, 22, 35.
Gershon, M. D. (2011). Behind an enteric neuron there may lie a glial cell. The Journal of Clinical Investigation, 121, 3386-3389.
Ghosh, M., Yang, Y., Rothstein, J. D., & Robinson, M. B. (2011). Nuclear factor-B contributes to neuron-dependent induction of glutamate transporter-1 expression in astrocytes. Journal of Neuroscience, 31, 9159-9169.
Gilbert-Jaramillo, J., Garcez, P., James, W., Molnár, Z., & Clarke, K. (2019). The potential contribution of impaired brain glucose metabolism to congenital Zika syndrome. Journal of Anatomy, 235, 468-480.
Gim, E., Shim, D.-W., Hwang, I., Shin, O. S., & Yu, J.-W. (2019). Zika virus impairs host NLRP3-mediated inflammasome activation in an NS3-dependent manner. Immune Network, 19, e40.
Greenhalgh, A. D., David, S., & Bennett, F. C. (2020). Immune cell regulation of glia during CNS injury and disease. Nature Reviews. Neuroscience, 21, 139-152.
Gundersen, V., Storm-Mathisen, J., & Bergersen, L. H. (2015). Neuroglial transmission. Physiological Reviews, 95, 695-726.
Henriques-Souza, A., de Azevedo Marques, E. T., Antunes de Brito, C. A., Brito Ferreira, M. L., de Morais Machado, M. Í., Pena, L. J., Cordeiro, M. T., & Moreira, Á. J. P. (2017). Guillain-Barré syndrome, acute disseminated encephalomyelitis and encephalitis associated with Zika virus infection in Brazil: Detection of viral RNA and isolation of virus during late infection. The American Journal of Tropical Medicine and Hygiene, 97, 1405-1409.
Hsu, D. C., Chumpolkulwong, K., Corley, M. J., Hunsawong, T., Inthawong, D., Schuetz, A., Imerbsin, R., Silsorn, D., Nadee, P., Sopanaporn, J., Phuang-Ngern, Y., Klungthong, C., Reed, M., Fernandez, S., Ndhlovu, L. C., Paul, R., Lugo-Roman, L., Michael, N. L., Modjarrad, K., & Vasan, S. (2022). Neurocognitive impact of Zika virus infection in adult rhesus macaques. Journal of Neuroinflammation, 19, 40.
Huang, Y., Li, Y., Zhang, H., Zhao, R., Jing, R., Xu, Y., He, M., Peer, J., Kim, Y. C., Luo, J., Tong, Z., & Zheng, J. (2018). Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869. Cell Discovery, 4, 19.
Hughes, M. M., & O'Neill, L. A. J. (2018). Metabolic regulation of NLRP3. Immunological Reviews, 281, 88-98.
Inglis, F. M., Lee, K. M., Chiu, K. B., Purcell, O. M., Didier, P. J., Russell-Lodrigue, K., Weaver, S. C., Roy, C. J., & MacLean, A. G. (2016). Neuropathogenesis of chikungunya infection: Astrogliosis and innate immune activation. Journal of Neurovirology, 22, 140-148.
Ireland, D. D. C., Manangeeswaran, M., Lewkowicz, A. P., Engel, K., Clark, S. M., Laniyan, A., Sykes, J., Lee, H.-N., McWilliams, I. L., Kelley-Baker, L., Tonelli, L. H., & Verthelyi, D. (2020). Long-term persistence of infectious Zika virus: Inflammation and behavioral sequela in mice. PLoS Pathogens, 16, e1008689.
Jäkel, S., & Dimou, L. (2017). Glial cells and their function in the adult brain: A journey through the history of their ablation. Frontiers in Cell Neuroscience, 11. https://doi.org/10.3389/fncel.2017.00024.
Jhan, M.-K., Chen, C.-L., Shen, T.-J., Tseng, P.-C., Wang, Y.-T., Satria, R. D., Yu, C.-Y., & Lin, C.-F. (2021). Polarization of type 1 macrophages is associated with the severity of viral encephalitis caused by Japanese encephalitis virus and dengue virus. Cell, 10, 3181.
Jiwaji, Z., & Hardingham, G. E. (2022). Good, bad, and neglectful: Astrocyte changes in neurodegenerative disease. Free Radical Biology and Medicine, 182, 93-99.
Kung, P.-L., Chou, T.-W., Lindman, M., Chang, N. P., Estevez, I., Buckley, B. D., Atkins, C., & Daniels, B. P. (2022). Zika virus-induced TNF-α signaling dysregulates expression of neurologic genes associated with psychiatric disorders. Journal of Neuroinflammation, 19, 100.
Labzin, L. I., Heneka, M. T., & Latz, E. (2018). Innate immunity and neurodegeneration. Annual Review of Medicine, 69, 437-449.
Leal, M. C., Muniz, L. F., Ferreira, T. S. A., Santos, C. M., Almeida, L. C., Van Der Linden, V., Ramos, R. C. F., Rodrigues, L. C., & Neto, S. S. C. (2016). Hearing loss in infants with microcephaly and evidence of congenital Zika virus infection - Brazil, November 2015-may 2016. MMWR. Morbidity and Mortality Weekly Report, 65, 917-919.
Ledur, P. F., Karmirian, K., da Pedrosa, C. S. G., LRQ, S., Assis-de-Lemos, G., Martins, T. M., de Ferreira, J. C. C. G., de Azevedo Reis, G. F., Silva, E. S., Silva, D., Salerno, J. A., Ornelas, I. M., Devalle, S., da Costa Madeiro, R. F., Goto-Silva, L., Higa, L. M., Melo, A., Tanuri, A., Chimelli, L., … Rehen, S. K. (2020). Zika virus infection leads to mitochondrial failure, oxidative stress and DNA damage in human iPSC-derived astrocytes. Scientific Reports, 10, 1218.
Lee, S.-E., Choi, H., Shin, N., Kong, D., Kim, N. G., Kim, H.-Y., Kim, M.-J., Choi, S. W., Kim, Y. B., & Kang, K.-S. (2022). Zika virus infection accelerates Alzheimer's disease phenotypes in brain organoids. Cell Death Discovery, 8, 153.
Lewerenz, J., & Maher, P. (2015). Chronic glutamate toxicity in neurodegenerative diseases-What is the evidence? Frontiers in Neuroscience,9:469. https://doi.org/10.3389/fnins.2015.00469.
Li, C., Deng, Y.-Q., Zu, S., Quanquin, N., Shang, J., Tian, M., Ji, X., Zhang, N.-N., Dong, H.-L., Xu, Y.-P., Zhao, L.-Z., Zhang, F.-C., Li, X.-F., Wu, A., Cheng, G., & Qin, C.-F. (2018). Zika virus shedding in the stool and infection through the anorectal mucosa in mice. Emerging Microbes & Infections, 7, 1-10.
Li, C., Wang, Q., Jiang, Y., Ye, Q., Xu, D., Gao, F., Xu, J. W., Wang, R., Zhu, X., Shi, L., Yu, L., Zhang, F., Guo, W., Zhang, L., Qin, C.-F., & Xu, Z. (2018). Disruption of glial cell development by Zika virus contributes to severe microcephalic newborn mice. Cell Discovery, 4, 43.
Li, L., Acioglu, C., Heary, R. F., & Elkabes, S. (2021). Role of astroglial toll-like receptors (TLRs) in central nervous system infections, injury and neurodegenerative diseases. Brain, Behavior, and Immunity, 91, 740-755.
Liang, Q., Luo, Z., Zeng, J., Chen, W., Foo, S.-S., Lee, S.-A., Ge, J., Wang, S., Goldman, S. A., Zlokovic, B. V., Zhao, Z., & Jung, J. U. (2016). Zika virus NS4A and NS4B proteins deregulate Akt-mTOR signaling in human fetal neural stem cells to inhibit neurogenesis and induce autophagy. Cell Stem Cell, 19, 663-671.
Lima, M. C., de Mendonça, L. R., Rezende, A. M., Carrera, R. M., Aníbal-Silva, C. E., Demers, M., D'Aiuto, L., Wood, J., Chowdari, K. V., Griffiths, M., Lucena-Araujo, A. R., Barral-Netto, M., Azevedo, E. A. N., Alves, R. W., Farias, P. C. S., Marques, E. T. A., Castanha, P. M. S., Donald, C. L., Kohl, A., … Franca, R. F. O. (2019). The transcriptional and protein profile from human infected neuroprogenitor cells is strongly correlated to Zika virus microcephaly cytokines phenotype evidencing a persistent inflammation in the CNS. Frontiers in Immunology, 10, 1928.
Lindqvist, R., Mundt, F., Gilthorpe, J. D., Wölfel, S., Gekara, N. O., Kröger, A., & Överby, A. K. (2016). Fast type I interferon response protects astrocytes from flavivirus infection and virus-induced cytopathic effects. Journal of Neuroinflammation, 13, 277.
Lum, F.-M., Low, D. K. S., Fan, Y., Tan, J. J. L., Lee, B., Chan, J. K. Y., Rénia, L., Ginhoux, F., & Ng, L. F. P. (2017). Zika virus infects human fetal brain microglia and induces inflammation. Clinical Infectious Diseases, 64, 914-920.
Lynch, M. A. (2020). Can the emerging field of immunometabolism provide insights into neuroinflammation? Progress in Neurobiology, 184, 101719.
Mai, J. K., & Paxinos, G. (Eds.). (2012). The human nervous system (3rd ed.). Elsevier Academic Press.
Martínez, L. E., Garcia, G., Contreras, D., Gong, D., Sun, R., & Arumugaswami, V. (2020). Zika virus mucosal infection provides protective immunity. Journal of Virology, 94, e00067-e00020.
Mattson, M. P., & Arumugam, T. V. (2018). Hallmarks of brain aging: Adaptive and pathological modification by metabolic states. Cell Metabolism, 27, 1176-1199.
Maucourant, C., Queiroz, G. A. N., Samri, A., Grassi, M. F. R., Yssel, H., & Vieillard, V. (2019). Zika virus in the eye of the cytokine storm. European Cytokine Network, 30, 74-81.
Mauro, C., Leow, S. C., Anso, E., Rocha, S., Thotakura, A. K., Tornatore, L., Moretti, M., De Smaele, E., Beg, A. A., Tergaonkar, V., Chandel, N. S., & Franzoso, G. (2011). NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration. Nature Cell Biology, 13, 1272-1279.
Meertens, L., Labeau, A., Dejarnac, O., Cipriani, S., Sinigaglia, L., Bonnet-Madin, L., Le Charpentier, T., Hafirassou, M. L., Zamborlini, A., Cao-Lormeau, V.-M., Coulpier, M., Missé, D., Jouvenet, N., Tabibiazar, R., Gressens, P., Schwartz, O., & Amara, A. (2017). Axl mediates ZIKA virus entry in human glial cells and modulates innate immune responses. Cell Reports, 18, 324-333.
Mehta, A., Prabhakar, M., Kumar, P., Deshmukh, R., & Sharma, P. L. (2013). Excitotoxicity: Bridge to various triggers in neurodegenerative disorders. European Journal of Pharmacology, 698, 6-18.
Mlakar, J., Korva, M., Tul, N., Popović, M., Poljšak-Prijatelj, M., Mraz, J., Kolenc, M., Resman Rus, K., Vesnaver Vipotnik, T., Fabjan Vodušek, V., Vizjak, A., Pižem, J., Petrovec, M., & Avšič, Ž. T. (2016). Zika virus associated with microcephaly. The New England Journal of Medicine, 374, 951-958.
Molina-Gonzalez, I., Miron, V. E., & Antel, J. P. (2022). Chronic oligodendrocyte injury in central nervous system pathologies. Communications Biology, 5, 1274.
Musso, D., Ko, A. I., & Baud, D. (2019). Zika virus infection - After the pandemic. The New England Journal of Medicine, 381, 1444-1457.
Mutso, M., St John, J. A., Ling, Z. L., Burt, F. J., Poo, Y. S., Liu, X., Žusinaite, E., Grau, G. E., Hueston, L., Merits, A., King, N. J. C., Ekberg, J. A. K., & Mahalingam, S. (2020). Basic insights into Zika virus infection of neuroglial and brain endothelial cells. Journal of General Virology, 101, 622-634.
Oh, Y., Zhang, F., Wang, Y., Lee, E. M., Choi, I. Y., Lim, H., Mirakhori, F., Li, R., Huang, L., Xu, T., Wu, H., Li, C., Qin, C.-F., Wen, Z., Wu, Q.-F., Tang, H., Xu, Z., Jin, P., Song, H., … Lee, G. (2017). Zika virus directly infects peripheral neurons and induces cell death. Nature Neuroscience, 20, 1209-1212.
Ojha, C. R., Rodriguez, M., Karuppan, M. K. M., Lapierre, J., Kashanchi, F., & El-Hage, N. (2019). Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes. PLoS One, 14, e0208543.
Olmo, I. G., Carvalho, T. G., Costa, V. V., Alves-Silva, J., Ferrari, C. Z., Izidoro-Toledo, T. C., da Silva, J. F., Teixeira, A. L., Souza, D. G., Marques, J. T., Teixeira, M. M., Vieira, L. B., & Ribeiro, F. M. (2017). Zika virus promotes neuronal cell death in a non-cell autonomous manner by triggering the release of neurotoxic factors. Frontiers in Immunology, 8, 1016.
Orellana, J. A., Froger, N., Ezan, P., Jiang, J. X., Bennett, M. V. L., Naus, C. C., Giaume, C., & Sáez, J. C. (2011). ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels. Journal of Neurochemistry, 118, 826-840.
Palsson-McDermott, E. M., Curtis, A. M., Goel, G., Lauterbach, M. A. R., Sheedy, F. J., Gleeson, L. E., van den Bosch, M. W. M., Quinn, S. R., Domingo-Fernandez, R., Johnston, D. G. W., Jiang, J., Israelsen, W. J., Keane, J., Thomas, C., Clish, C., Vander Heiden, M., Xavier, R. J., & O'Neill, L. A. J. (2015). Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the Warburg effect in LPS-activated macrophages. Cell Metabolism, 21, 65-80.
Petersen, L. R., Jamieson, D. J., Powers, A. M., & Honein, M. A. (2016). Zika virus. The New England Journal of Medicine, 374, 1552-1563.
Quincozes-Santos, A., Santos, C. L., de Souza Almeida, R. R., da Silva, A., Thomaz, N. K., Costa, N. L. F., Weber, F. B., Schmitz, I., Medeiros, L. S., Medeiros, L., Dotto, B. S., Dias, F. R. P., Sovrani, V., & Bobermin, L. D. (2021). Gliotoxicity and glioprotection: The dual role of glial cells. Molecular Neurobiology, 58, 6577-6592.
Rawal, G., Yadav, S., & Kumar, R. (2016). Zika virus: An overview. Journal of Family Medicine and Primary Care, 5, 523-527.
Retallack, H., Di Lullo, E., Arias, C., Knopp, K. A., Laurie, M. T., Sandoval-Espinosa, C., Mancia Leon, W. R., Krencik, R., Ullian, E. M., Spatazza, J., Pollen, A. A., Mandel-Brehm, C., Nowakowski, T. J., Kriegstein, A. R., & DeRisi, J. L. (2016). Zika virus cell tropism in the developing human brain and inhibition by Azithromycin. Proceedings of the National Academy of Sciences of the United States of America, 113, 14408-14413.
Rombi, F., Bayliss, R., Tuplin, A., & Yeoh, S. (2020). The journey of Zika to the developing brain. Molecular Biology Reports, 47, 3097-3115.
Rossi, F., Josey, B., Sayitoglu, E. C., Potens, R., Sultu, T., Duru, A. D., & Beljanski, V. (2020). Characterization of Zika virus infection of human fetal cardiac mesenchymal stromal cells. PLoS One, 15, e0239238.
Rudy, C. C., Hunsberger, H. C., Weitzner, D. S., & Reed, M. N. (2015). The role of the tripartite glutamatergic synapse in the pathophysiology of Alzheimer's disease. Aging and Disease, 6, 131-148.
Ryan, F. J., Carr, J. M., Furtado, J. M., Ma, Y., Ashander, L. M., Simões, M., Oliver, G. F., Granado, G. B., Dawson, A. C., Michael, M. Z., Appukuttan, B., Lynn, D. J., & Smith, J. R. (2021). Zika virus infection of human iris pigment epithelial cells. Frontiers in Immunology, 12, 644153.
Santi, L., Riesgo, R. S., Quincozes-Santos, A., Schuler-Faccini, L., Tureta, E. F., Rosa, R. L., Berger, M., Oliveira, A. C. C., Beltrão-Braga, P. C. B., Souza, D. O., Guimarães, J. A., & Beys-da-Silva, W. O. (2021). Zika virus infection associated with autism spectrum disorder: A case report. Neuroimmunomodulation, 28, 229-232.
Schouest, B., Peterson, T. A., Szeltner, D. M., Scheef, E. A., Baddoo, M., Ungerleider, N., Flemington, E. K., MacLean, A. G., & Maness, N. J. (2021). Transcriptional signatures of Zika virus infection in astrocytes. Journal of Neurovirology, 27, 116-125.
Schreiner, B., Romanelli, E., Liberski, P., Ingold-Heppner, B., Sobottka-Brillout, B., Hartwig, T., Chandrasekar, V., Johannssen, H., Zeilhofer, H. U., Aguzzi, A., Heppner, F., Kerschensteiner, M., & Becher, B. (2015). Astrocyte depletion impairs redox homeostasis and triggers neuronal loss in the adult CNS. Cell Reports, 12, 1377-1384.
Schuler-Faccini, L., del Campo, M., García-Alix, A., Ventura, L. O., Boquett, J. A., van der Linden, V., Pessoa, A., van der Linden, J. H., Ventura, C. V., Leal, M. C., Kowalski, T. W., Rodrigues Gerzson, L., Skilhan de Almeida, C., Santi, L., Beys-da-Silva, W. O., Quincozes-Santos, A., Guimarães, J. A., Garcez, P. P., do Gomes, J. A., … Souza, D. O. (2022). Neurodevelopment in children exposed to Zika in utero: Clinical and molecular aspects. Frontiers in Genetics, 13, 758715.
Schultz, V., Barrie, J. A., Donald, C. L., Crawford, C. L., Mullin, M., Anderson, T. J., Solomon, T., Barnett, S. C., Linington, C., Kohl, A., Willison, H. J., & Edgar, J. M. (2021). Oligodendrocytes are susceptible to Zika virus infection in a mouse model of perinatal exposure: Implications for CNS complications. Glia, 69, 2023-2036.
Schultz, V., Cumberworth, S. L., Gu, Q., Johnson, N., Donald, C. L., McCanney, G. A., Barrie, J. A., Da Silva, F. A., Linington, C., Willison, H. J., Edgar, J. M., Barnett, S. C., & Kohl, A. (2021). Zika virus infection leads to demyelination and axonal injury in mature CNS cultures. Viruses, 13, 91.
Shad, K. F., Soubra, W., & Cordato, D. J. (2022). The auditory afferent pathway as a clinical marker of Alzheimer's disease. JAD, 85, 47-53.
Shang, J., Li, C., Jin, Z., Zu, S., Chen, S., Chen, J., Chen, Z., Tang, H., Qin, C.-F., Ye, Q., & Wu, A. (2022). Immune profiles in mouse brain and testes infected by Zika virus with variable pathogenicity. Frontiers in Cellular and Infection Microbiology, 12, 948980.
Shereen, M. A., Bashir, N., Su, R., Liu, F., Wu, K., Luo, Z., & Wu, J. (2021). Zika virus dysregulates the expression of astrocytic genes involved in neurodevelopment. PLoS Neglected Tropical Diseases, 15, e0009362.
Sirohi, D., & Kuhn, R. J. (2017). Can an FDA-approved Alzheimer's drug be repurposed for alleviating neuronal symptoms of Zika virus? MBio, 8, 1-6.
St. John, J. A., Walkden, H., Nazareth, L., Beagley, K. W., Ulett, G. C., Batzloff, M. R., Beacham, I. R., & Ekberg, J. A. K. (2016). Burkholderia pseudomallei rapidly infects the brain stem and spinal cord via the trigeminal nerve after intranasal inoculation. Infection and Immunity, 84, 2681-2688.
Stefanik, M., Formanova, P., Bily, T., Vancova, M., Eyer, L., Palus, M., Salat, J., Braconi, C. T., de Zanotto, P. M. A., Gould, E. A., & Ruzek, D. (2018). Characterisation of Zika virus infection in primary human astrocytes. BMC Neuroscience, 19, 5.
Tricarico, P. M., Caracciolo, I., Crovella, S., & D'Agaro, P. (2017). Zika virus induces inflammasome activation in the glial cell line U87-MG. Biochemical and Biophysical Research Communications, 492, 597-602.
Ubeda-Bañon, I., Saiz-Sanchez, D., Flores-Cuadrado, A., Rioja-Corroto, E., Gonzalez-Rodriguez, M., Villar-Conde, S., Astillero-Lopez, V., Cabello-de la Rosa, J. P., Gallardo-Alcañiz, M. J., Vaamonde-Gamo, J., Relea-Calatayud, F., Gonzalez-Lopez, L., Mohedano-Moriano, A., Rabano, A., & Martinez-Marcos, A. (2020). The human olfactory system in two proteinopathies: Alzheimer's and Parkinson's diseases. Translational Neurodegeneration, 9, 22.
Vainchtein, I. D., & Molofsky, A. V. (2020). Astrocytes and microglia: In sickness and in health. Trends in Neurosciences, 43, 144-154.
Vardjan, N., Parpura, V., Verkhratsky, A., & Zorec, R. (2019). Gliocrine system: Astroglia as secretory cells of the CNS. Advances in Experimental Medicine and Biology, 1175, 93-115.
Vardjan, N., & Zorec, R. (2015). Excitable astrocytes: Ca2+− and cAMP-regulated exocytosis. Neurochemical Research, 40, 2414-2424.
Veríssimo, C. P., da Carvalho, J. S., da Silva, F. J. M., Campanati, L., Moura-Neto, V., & de Coelho-Aguiar, J. M. (2019). Laminin and environmental cues act in the inhibition of the neuronal differentiation of enteric glia in vitro. Frontiers in Neuroscience, 13, 914.
Verkhratsky, A., Ho, M. S., Zorec, R., & Parpura, V. (2019). The concept of neuroglia. In A. Verkhratsky, M. S. Ho, R. Zorec, & V. Parpura (Eds.), Neuroglia in neurodegenerative diseases. Advances in experimental medicine and biology (Vol. 1175, pp. 1-13). Springer Singapore.
Verma, M., Lizama, B. N., & Chu, C. T. (2022). Excitotoxicity, calcium and mitochondria: A triad in synaptic neurodegeneration. Translational Neurodegeneration, 11, 3.
Vianna, P., do Gomes, J. A., Boquett, J. A., Fraga, L. R., Schuch, J. B., FSL, V., & Schuler-Faccini, L. (2018). Zika virus as a possible risk factor for autism spectrum disorder: Neuroimmunological aspects. Neuroimmunomodulation, 25, 320-327.
Vizuete, A. F. K., Fróes, F., Seady, M., Zanotto, C., Bobermin, L. D., Roginski, A. C., Wajner, M., Quincozes-Santos, A., & Gonçalves, C. A. (2022). Early effects of LPS-induced neuroinflammation on the rat hippocampal glycolytic pathway. Journal of Neuroinflammation, 19, 255.
Volpi, V. G., Pagani, I., Ghezzi, S., Iannacone, M., D'Antonio, M., & Vicenzi, E. (2018). Zika virus replication in dorsal root ganglia explants from interferon Receptor1 knockout mice causes myelin degeneration. Scientific Reports, 8, 10166.
Wang, J., Liu, J., Zhou, R., Ding, X., Zhang, Q., Zhang, C., & Li, L. (2018). Zika virus infected primary microglia impairs NPCs proliferation and differentiation. Biochemical and Biophysical Research Communications, 497, 619-625.
Wu, S., Zeng, Y., Lerner, A., Gao, B., & Law, M. (2018). Nervous system injury and neuroimaging of Zika virus infection. Frontiers in Neurology, 9, 227.
Yang, H., Li, S., & Le, W. (2022). Intestinal permeability, dysbiosis, inflammation and enteric glia cells: The intestinal etiology of Parkinson's disease. Aging and Disease, 13, 1381-1390.
Yang, J., Vitery, M. D. C., Chen, J., Osei-Owusu, J., Chu, J., & Qiu, Z. (2019). Glutamate-releasing SWELL1 channel in astrocytes modulates synaptic transmission and promotes brain damage in stroke. Neuron, 102, 813-827.e6.
Ye, Z.-C., Wyeth, M. S., Baltan-Tekkok, S., & Ransom, B. R. (2003). Functional hemichannels in astrocytes: A novel mechanism of glutamate release. The Journal of Neuroscience, 23, 3588-3596.
Zafar, M. I., Yu, J., & Li, H. (2021). Implications of RNA viruses in the male reproductive tract: An outlook on SARS-CoV-2. Frontiers in Microbiology, 12, 783963.
Zhang, F., Wang, H.-J., Wang, Q., Liu, Z.-Y., Yuan, L., Huang, X.-Y., Li, G., Ye, Q., Yang, H., Shi, L., Deng, Y.-Q., Qin, C.-F., & Xu, Z. (2017). American strain of Zika virus causes more severe microcephaly than an old Asian strain in neonatal mice. eBioMedicine, 25, 95-105.
Zorec, R., Parpura, V., & Verkhratsky, A. (2018). Astroglial vesicular network: Evolutionary trends, physiology and pathophysiology. Acta Physiologica, 222(2). https://doi.org/10.1111/apha.12915.
فهرسة مساهمة: Keywords: Zika virus; glial cells; inflammatory response; neurodegeneration; neuron-glia communication
تواريخ الأحداث: Date Created: 20230303 Date Completed: 20230613 Latest Revision: 20230621
رمز التحديث: 20230621
DOI: 10.1002/glia.24353
PMID: 36866453
قاعدة البيانات: MEDLINE
الوصف
تدمد:1098-1136
DOI:10.1002/glia.24353