دورية أكاديمية
Associations between duration of first trimester intrauterine exposure to genocide against the Tutsi and health outcomes in adulthood.
العنوان: | Associations between duration of first trimester intrauterine exposure to genocide against the Tutsi and health outcomes in adulthood. |
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المؤلفون: | Uwizeye G; Arthur Labatt Family School of Nursing, Western University, London, Ontario, Canada., Rutherford JN; Biobehavioral Health Sciences Division, College of Nursing, University of Arizona, Tucson, Arizona, USA., Thayer ZM; Department of Anthropology, Dartmouth College, Hanover, New Hampshire, USA. |
المصدر: | American journal of biological anthropology [Am J Biol Anthropol] 2023 Jul; Vol. 181 (3), pp. 341-351. Date of Electronic Publication: 2023 Mar 03. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: John Wiley & Sons Inc Country of Publication: United States NLM ID: 101770171 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2692-7691 (Electronic) Linking ISSN: 26927691 NLM ISO Abbreviation: Am J Biol Anthropol Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: [Hoboken, NJ] : John Wiley & Sons Inc., [2022]- |
مواضيع طبية MeSH: | Anxiety Disorders* , Genocide*/psychology, Adult ; Female ; Pregnancy ; Humans ; Rwanda/epidemiology ; Pregnancy Trimester, First ; Outcome Assessment, Health Care |
مستخلص: | Objectives: Hundreds of thousands of Rwandans were conceived during the 1994 genocide against the Tutsi, including thousands conceived by genocidal rape. We explore whether the duration of first trimester exposure to the genocide is associated with variation in adult mental health outcomes in individuals exposed to varying degrees of genocide-related stress in utero. Materials and Methods: We recruited 30 Rwandans conceived via genocidal rape, 31 Rwandans conceived by genocide survivors not raped, and 30 individuals of Rwandan-descent who were conceived outside of Rwanda at the time of the genocide (control group). Individuals were age- and sex-matched across groups. Adult mental health was assessed through standardized questionnaires for vitality, anxiety, and depression. Results: Among the genocide only group, a longer duration of first trimester prenatal exposure was associated with higher anxiety scores and lower vitality (both p < 0.010), and higher depression scores (p = 0.051). Duration of first trimester exposure was not associated with any measures of mental health among the genocidal rape or control group. Discussion: Duration of exposure to genocide in the first trimester of gestation was associated with variation in adult mental health among the genocide only group. The lack of association between duration of first trimester exposure to genocide and adult mental health in the genocidal rape group may reflect the fact that stress associated with conception through rape persisted beyond the genocide period itself, encompassing all of gestation and likely beyond. Geopolitical and community interventions are needed in the context of extreme events during pregnancy to mitigate adverse intergenerational outcomes. (© 2023 The Authors. American Journal of Biological Anthropology published by Wiley Periodicals LLC.) |
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فهرسة مساهمة: | Keywords: anxiety; depression; developmental origins of health and disease; first trimester; prenatal stress exposure; vitality |
تواريخ الأحداث: | Date Created: 20230303 Date Completed: 20230621 Latest Revision: 20230623 |
رمز التحديث: | 20231215 |
DOI: | 10.1002/ajpa.24708 |
PMID: | 36866929 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2692-7691 |
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DOI: | 10.1002/ajpa.24708 |