دورية أكاديمية
Sight the Mite: A Meta-Analysis on the Diagnosis of Scabies.
| العنوان: | Sight the Mite: A Meta-Analysis on the Diagnosis of Scabies. |
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| المؤلفون: | Shoukat Q; College of Medicine, Dr. Kiran C. Patel College of Allopathic Medicine, Nova Southeastern University, Davie, USA., Rizvi A; College of Medicine, Dr. Kiran C. Patel College of Allopathic Medicine, Nova Southeastern University, Davie, USA., Wahood W; College of Medicine, Dr. Kiran C. Patel College of Allopathic Medicine, Nova Southeastern University, Davie, USA., Coetzee S; Medicine, Dr. Kiran C. Patel College of Allopathic Medicine, Nova Southeastern University, Davie, USA., Wrench A; Microbiology, Nova Southeastern University, Fort Lauderdale, USA. |
| المصدر: | Cureus [Cureus] 2023 Jan 30; Vol. 15 (1), pp. e34390. Date of Electronic Publication: 2023 Jan 30 (Print Publication: 2023). |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Palo Alto, CA : Cureus, Inc. |
| مستخلص: | This meta-analysis was performed to assess the efficacy of the diagnostic tests for scabies infections that are currently in wide use. Scabies is most commonly diagnosed through clinical presentations; however, due to the wide array of symptoms, diagnosis is difficult. The most commonly used diagnostic test is skin scraping. However, this test relies on correctly selecting the site of mite infection for sampling. Due to the mobile nature of a live parasitic infection, the mite can often be missed based on its current location within the skin. The goal of this paper is to determine if a gold standard confirmatory test exists for the diagnosis of scabies by comparing Skin Scraping, Adhesive Tape, Dermoscopy, and PCR tests. Medline, PubMed, and Neglected Tropical Diseases databases were utilized in a literature review. Eligible papers were papers published in or after the year 2000, published in the English language, and mainly focused on the diagnosis of scabies. At the time of this meta-analysis, scabies is mostly diagnosed through a correlation of clinical symptoms in conjunction with diagnostic tests such as dermoscopy (sensitivity: 43.47%, specificity: 84.41%), adhesive tape tests (sensitivity: 69.56%, specificity: 100%) and PCR antigen detection (37.9% sensitivity, specificity: 100%). Due to a scarcity of data in the literature, the diagnostic efficacy of other diagnostic tests is difficult to assess. Overall, the efficacies of the tests analyzed vary depending on how similar scabies is to other skin disorders, how challenging it is to get a usable sample and the price and accessibility of essential tools. There is a need for standardized national diagnostic criteria to increase the diagnostic sensitivity of scabies infection. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Shoukat et al.) |
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| فهرسة مساهمة: | Keywords: diagnosis of scabies; diagnostic test accuracy; diagnostic testing; infectious and parasitic diseases; neglected (re)emergent tropical disease; neglected disease; parasitic disease; sarcoptes scabiei var. hominis; systematic review and meta analysis; systematic review and meta-analysis |
| تواريخ الأحداث: | Date Created: 20230306 Latest Revision: 20230307 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC9976840 |
| DOI: | 10.7759/cureus.34390 |
| PMID: | 36874720 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2168-8184 |
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| DOI: | 10.7759/cureus.34390 |