تقرير
Case report: Suspected plasmablastic lymphoma in a dog resembling the clinical presentation in humans.
| العنوان: | Case report: Suspected plasmablastic lymphoma in a dog resembling the clinical presentation in humans. |
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| المؤلفون: | Giuliano A; CityU Veterinary Medical Centre, City University of Hong Kong, Kowloon, Hong Kong SAR, China.; Department of Veterinary Clinical Sciences, Jockey Club College of Veterinary Medicine, City University of Hong Kong, Kowloon, Hong Kong SAR, China., Lam SY; Veterinary Emergency Center, Kennedy Town, Hong Kong SAR, China., Flecher MC; Department of Veterinary Medicine, Universidade Vila Velha, Vila Velha, ES, Brazil., Horta RS; Department of Veterinary Medicine and Surgery, Veterinary School, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. |
| المصدر: | Frontiers in veterinary science [Front Vet Sci] 2023 Feb 16; Vol. 10, pp. 1100942. Date of Electronic Publication: 2023 Feb 16 (Print Publication: 2023). |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101666658 Publication Model: eCollection Cited Medium: Print ISSN: 2297-1769 (Print) Linking ISSN: 22971769 NLM ISO Abbreviation: Front Vet Sci Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Lausanne : Frontiers Media S.A., [2014]- |
| مستخلص: | Plasmablastic lymphoma (PBL) is a rare form of lymphoma in people. PBL originates from plasmablasts and usually presents with swelling/mass in the mouth/neck. A 7-year-old Mongrel dog was presented for a large oral and neck mass. Cytology and histopathology were suggestive of a round cell tumor that was suspected to be lymphoma. An immunohistochemical (IHC) stain panel showed positive for CD18, thus supporting the diagnosis of round cell tumor, but negative for T- and B-cell lymphomas, CD3, CD20, and PAX-5. Other markers including cytokeratin AE1/3 (for epithelial cell origin), CD31 (for endothelial cells), SOX10 (for melanoma), IBa-1 (for histiocytic sarcoma), and CD117 (for mast cell tumor) were all negative. MUM-1 (for plasma cell differentiation) was strongly positive and CD79a (B cell and plasma cells) was also scantly positive. Based on the histopathology and immunohistochemistry results in combination with the clinical presentation, a suspected diagnosis of PBL was made. As per available literature, this is perhaps the first highly suspected case of PBL in a dog. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Giuliano, Lam, Flecher and Horta.) |
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| فهرسة مساهمة: | Keywords: B-cell; immunohistochemistry; lymphoma; neck mass; plasma cells |
| تواريخ الأحداث: | Date Created: 20230306 Latest Revision: 20230307 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC9978506 |
| DOI: | 10.3389/fvets.2023.1100942 |
| PMID: | 36875999 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2297-1769 |
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| DOI: | 10.3389/fvets.2023.1100942 |