دورية أكاديمية
Enhanced Bacterial Growth by Polyelemental Glycerolate Particles.
| العنوان: | Enhanced Bacterial Growth by Polyelemental Glycerolate Particles. |
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| المؤلفون: | Phakatkar AH; Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, Illinois 60607, United States., Gonçalves JM; Department of Mechanical & Industrial Engineering, University of Illinois at Chicago, Chicago, Illinois 60607, United States.; Department of Fundamental Chemistry, University of Sao Paulo, Sao Paulo, SP 05508-060, Brazil., Zhou J; Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, Illinois 60607, United States., Ritter TG; Department of Civil, Materials, and Environmental Engineering, University of Illinois at Chicago, Chicago, Illinois 60607, United States., Tamadoni Saray M; Department of Mechanical & Industrial Engineering, University of Illinois at Chicago, Chicago, Illinois 60607, United States., Sorokina LV; Department of Civil, Materials, and Environmental Engineering, University of Illinois at Chicago, Chicago, Illinois 60607, United States., Amiri A; Department of Mechanical & Industrial Engineering, University of Illinois at Chicago, Chicago, Illinois 60607, United States., Angnes L; Department of Fundamental Chemistry, University of Sao Paulo, Sao Paulo, SP 05508-060, Brazil., Shokuhfar T; Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, Illinois 60607, United States., Shahbazian-Yassar R; Department of Mechanical & Industrial Engineering, University of Illinois at Chicago, Chicago, Illinois 60607, United States. |
| المصدر: | ACS applied bio materials [ACS Appl Bio Mater] 2023 Apr 17; Vol. 6 (4), pp. 1515-1524. Date of Electronic Publication: 2023 Mar 18. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: ACS Publications Country of Publication: United States NLM ID: 101729147 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2576-6422 (Electronic) Linking ISSN: 25766422 NLM ISO Abbreviation: ACS Appl Bio Mater Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Washington, DC : ACS Publications, [2018]- |
| مواضيع طبية MeSH: | Escherichia coli* , Glycerol*/pharmacology, Cell Membrane ; Alloys |
| مستخلص: | While polyelemental alloys are shown to be promising for healthcare applications, their effectiveness in promoting bacterial growth remains unexplored. In the present work, we evaluated the interaction of polyelemental glycerolate particles (PGPs) with Escherichia coli ( E. coli ) bacteria. PGPs were synthesized using the solvothermal route, and nanoscale random distribution of metal cations in the glycerol matrix of PGPs was confirmed. We observed 7-fold growth of E. coli bacteria upon 4 h of interaction with quinary glycerolate (NiZnMnMgSr-Gly) particles in comparison to control E. coli bacteria. Nanoscale microscopic studies on bacteria interactions with PGPs showed the release of metal cations in the bacterium cytoplasm from PGPs. The electron microscopy imaging and chemical mapping indicated bacterial biofilm formation on PGPs without causing significant cell membrane damage. The data showed that the presence of glycerol in PGPs is effective in controlling the release of metal cations, thus preventing bacterial toxicity. The presence of multiple metal cations is expected to provide synergistic effects of nutrients needed for bacterial growth. The present work provides key microscopic insights of mechanisms by which PGPs enhance biofilm growth. This study opens the door for future applications of PGPs in areas where bacterial growth is essential including healthcare, clean energy, and the food industry. |
| فهرسة مساهمة: | Keywords: bacterial growth; glycerolate materials; in situ graphene liquid cell; nano-/biointeractions; polyelemental particles; transmission electron microscopy |
| المشرفين على المادة: | PDC6A3C0OX (Glycerol) 0 (Alloys) |
| تواريخ الأحداث: | Date Created: 20230318 Date Completed: 20230418 Latest Revision: 20230424 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1021/acsabm.2c01052 |
| PMID: | 36933270 |
| قاعدة البيانات: | MEDLINE |
Find this issue from the American Chemical Society | تدمد: | 2576-6422 |
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| DOI: | 10.1021/acsabm.2c01052 |